[go: up one dir, main page]

ES481128A1 - Procedimiento para la preparacion de nuevos derivados fenil-piperazinicos. - Google Patents

Procedimiento para la preparacion de nuevos derivados fenil-piperazinicos.

Info

Publication number
ES481128A1
ES481128A1 ES481128A ES481128A ES481128A1 ES 481128 A1 ES481128 A1 ES 481128A1 ES 481128 A ES481128 A ES 481128A ES 481128 A ES481128 A ES 481128A ES 481128 A1 ES481128 A1 ES 481128A1
Authority
ES
Spain
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
new substituted
phenylpiperazine derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES481128A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19782824677 external-priority patent/DE2824677A1/de
Priority claimed from DE19782853996 external-priority patent/DE2853996A1/de
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of ES481128A1 publication Critical patent/ES481128A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/34—Oxygen atoms in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Procedimiento para la preparación de nuevos derivados fenilpiperazínicos de la fórmula **(Fórmula)** Donde R1 significa hidrógeno o un grupo alcohilo C1-C6, R2 significa hidrógeno o uno o varios sustituyentes, iguales o diferentes, con el siguiente significado: alcohilo C1-C6, alcoxi C1-C6, halógeno, trifluorometilo, hidroxi, nitro, amino, metilendioxi, R3 significa hidrógeno, hidroxi, alcanoiloxi C1-C6, así como sus sales fisiológicamente compatibles y n significa 1 ó 2.
ES481128A 1978-06-06 1979-05-31 Procedimiento para la preparacion de nuevos derivados fenil-piperazinicos. Expired ES481128A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19782824677 DE2824677A1 (de) 1978-06-06 1978-06-06 Neue substituierte phenylpiperazinderivate und verfahren zu deren herstellung
DE19782853996 DE2853996A1 (de) 1978-12-14 1978-12-14 Neue substituierte phenylpiperazinderivate und verfahren zu deren herstellung

Publications (1)

Publication Number Publication Date
ES481128A1 true ES481128A1 (es) 1979-11-16

Family

ID=25774636

Family Applications (3)

Application Number Title Priority Date Filing Date
ES481126A Expired ES481126A1 (es) 1978-06-06 1979-05-31 Procedimiento para la preparacion de nuevos derivados fe- nilpiperazinicos.
ES481129A Expired ES481129A1 (es) 1978-06-06 1979-05-31 Procedimiento para la preparacion de nuevos derivados fenil-piperazinicos.
ES481128A Expired ES481128A1 (es) 1978-06-06 1979-05-31 Procedimiento para la preparacion de nuevos derivados fenil-piperazinicos.

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES481126A Expired ES481126A1 (es) 1978-06-06 1979-05-31 Procedimiento para la preparacion de nuevos derivados fe- nilpiperazinicos.
ES481129A Expired ES481129A1 (es) 1978-06-06 1979-05-31 Procedimiento para la preparacion de nuevos derivados fenil-piperazinicos.

Country Status (5)

Country Link
US (1) US4234584A (es)
EP (1) EP0005828B1 (es)
AU (1) AU4776179A (es)
DE (1) DE2960178D1 (es)
ES (3) ES481126A1 (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54130587A (en) * 1978-03-30 1979-10-09 Otsuka Pharmaceut Co Ltd Carbostyryl derivative
EP0025111B1 (en) * 1979-08-10 1984-07-25 Sandoz Ag 3-aminopropoxyaryl derivatives, their preparation and pharmaceutical compositions containing them
PH17194A (en) * 1980-03-06 1984-06-19 Otsuka Pharma Co Ltd Novel carbostyril derivatives,and pharmaceutical composition containing the same
DE3200304A1 (de) * 1981-01-16 1982-08-26 Sandoz-Patent-GmbH, 7850 Lörrach 3-aminopropoxyaryl-derivate, ihre herstellung und sie enthaltende arzneimittel
DE3424685A1 (de) * 1984-07-05 1986-02-06 Beiersdorf Ag, 2000 Hamburg Neue substituierte phenylpiperazinyl-propanole, verfahren zu ihrer herstellung und ihre verwendung sowie diese verbindungen enthaltende zubereitungen
DE3426419A1 (de) * 1984-07-18 1986-01-23 Boehringer Mannheim Gmbh, 6800 Mannheim Neue oxindol-derivate, verfahren zu ihrer herstellung, diese verbindungen enthaltende arzneimittel und zwischenprodukte
GB2163150B (en) * 1984-07-19 1988-05-25 Sandoz Ltd 3-aminopropoxyaryl derivatives
CN85108214A (zh) * 1984-11-22 1986-08-20 赫彻斯特股份公司 新的取代的苯基哌嗪衍生物及其药物的制造方法
DE3529994A1 (de) * 1985-08-22 1987-02-26 Hoechst Ag Indolinonderivate, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung
FR2589863B1 (fr) * 1985-11-12 1988-07-29 Sanofi Sa Derives d'hydroxy-4 indole, leur procede de preparation et leur utilisation
US5006528A (en) * 1988-10-31 1991-04-09 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivatives
WO2006103559A1 (en) * 2005-04-01 2006-10-05 Warner-Lambert Company Llc Tetrahydro-pyridoazepin-8-ones and related compounds for the treatment of schizophrenia
TWI320783B (en) 2005-04-14 2010-02-21 Otsuka Pharma Co Ltd Heterocyclic compound
TWI329641B (en) 2005-08-31 2010-09-01 Otsuka Pharma Co Ltd (benzo[b]thiophen-4-yl)piperazine compounds, pharmaceutical compositions comprising the same, uses of the same and processes for preparing the same
BRPI0912362A2 (pt) * 2008-05-09 2015-10-06 Univ Emory antagonista do receptor nmda para o tratamento de transtornos neuropsiquiátricos
EP4124616A1 (en) 2009-06-25 2023-02-01 Alkermes Pharma Ireland Limited Heterocyclic compounds for the treatment of neurological and psychological disorders
US8536328B2 (en) 2010-05-04 2013-09-17 Alkermes Pharma Ireland Limited Process for synthesizing oxidized lactam compounds
US8592427B2 (en) 2010-06-24 2013-11-26 Alkermes Pharma Ireland Limited Prodrugs of NH-acidic compounds: ester, carbonate, carbamate and phosphonate derivatives
CN112423754A (zh) 2018-03-05 2021-02-26 奥克梅斯制药爱尔兰有限公司 阿立哌唑的给药策略
CN117769545A (zh) * 2021-08-05 2024-03-26 上海枢境生物科技有限公司 含三并环类衍生物调节剂、其制备方法和应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH534687A (de) * 1968-07-05 1973-03-15 Cassella Farbwerke Mainkur Ag Verfahren zur Herstellung von Derivaten des 2-Oxo-1,2-dihydro-chinolins
US3910924A (en) * 1972-04-13 1975-10-07 Otsuka Pharma Co Ltd 3,4-Dihydrocarbostyril derivatives and a process for preparing the same
JPS517672B2 (es) * 1972-04-13 1976-03-10
DE2263211A1 (de) * 1972-12-23 1974-07-04 Boehringer Sohn Ingelheim Neue arylpiperazine und verfahren zu ihrer herstellung
DE2337461A1 (de) * 1973-07-24 1975-02-06 Boehringer Mannheim Gmbh Neue indolderivate und verfahren zu deren herstellung
DE2525656A1 (de) * 1974-06-19 1976-01-15 Sandoz Ag Verfahren zur herstellung neuer heterocyclischer verbindungen
DE2719562C2 (de) * 1976-05-08 1986-05-07 Otsuka Pharmaceutical Co. Ltd., Tokio/Tokyo 3, 4-Dihydrocarbostyrilderivate, Verfahren zu deren Herstellung und Arzneimittel, welche diese enthalten
DE2737630A1 (de) * 1977-08-20 1979-03-01 Boehringer Mannheim Gmbh Neue aminopropanolderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Also Published As

Publication number Publication date
AU4776179A (en) 1979-12-13
EP0005828A1 (de) 1979-12-12
US4234584A (en) 1980-11-18
DE2960178D1 (en) 1981-04-09
ES481129A1 (es) 1979-11-16
EP0005828B1 (de) 1981-03-11
ES481126A1 (es) 1979-11-16

Similar Documents

Publication Publication Date Title
ES481128A1 (es) Procedimiento para la preparacion de nuevos derivados fenil-piperazinicos.
ES8202799A1 (es) Procedimiento para la preparacion de sulfonilureas
IL96407A0 (en) Diazine derivatives
DE3366141D1 (en) 1-phenylisoquinoline derivatives, process for their preparation, pharmaceutical compositions containing these compounds and their use
IL114537A (en) Sulfonamide derivatives of azolones their preparation and pharmaceutical compositions containing them
IL105801A (en) 7-(2-aminoethyl)-benzothiazolones their preparation and pharmaceutical compositions containing them
ATE10368T1 (de) Uracilderivate, verfahren zu ihrer herstellung und eine diese enthaltende pharmazeutische zubereitung.
HUT52040A (en) Process for producing diaryl-derivatives and pharmaceutical compositions containing them
IL61333A0 (en) Secondary amines, their preparation and pharmaceutical compositions containing them
ATE91682T1 (de) Alkansulfonanilid-derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzung.
ATE4203T1 (de) 4-aryloxy- und 4-arylthio-3-phenylpiperidinderivate, verfahren zur herstellung solcher verbindungen und diese enthaltende pharmazeutische zusammensetzungen.
FI833200A (fi) Isokinolinderivat, foerfaranden foer deras framstaellning, pao dessa foereningar baserade farmaceutpreparat och deras anvaendning
ES8304977A1 (es) "procedimiento para la preparacion de derivados triptaminicos sustituidos de tieniloxipropanolaminas, racemicos y opticamente activos".
ES8504190A1 (es) Procedimiento para la preparacion de nuevos derivados del acido quinolicincarboxilico.
DE3378120D1 (en) Thiazaspiro derivatives, process for their preparation and pharmaceutical composition
ATE46172T1 (de) Verbindungen, diese enthaltende pharmazeutische zusammensetzungen und verfahren zur herstellung.
ES8401946A1 (es) Procedimiento para la preparacion de sulfonilureas.
ES474694A1 (es) Un procedimiento de preparacion de nuevos derivados de las 5h-benzociclohepten-7-amina
SE9203824L (sv) Bensofuranylimidazol-derivat, foerfarande foer framstaellning daerav och terapeutiska kompositioner innehaallande desamma
ES2027492A6 (es) Procedimiento de preparacion de nuevos derivados dihidropirimidotiazinos y de sus sales de adicion acidas farmaceuticamente aceptables.
HUT57227A (en) 2'-dezamino-4'-desoxy-4'-amino-8-fluoro-anthracycline derivatives, process for producing them as well as pharmaceutical preparatives containing said compounds as active substance
ES8403116A1 (es) Procedimiento para la preparacion de pirido (1,4) benzodiazepinas.
IL67400A0 (en) 3,7alpha-diazacyclohepta(j,k)fluorene derivatives,their preparation and pharmaceutical compositions containing them
ES8203876A1 (es) Procedimiento de obtencion de nuevos a-amino derivados ci- clicos del 1-(3',4'-metilendioxifenil)etanol
ES8107219A1 (es) Procedimiento para la preparacion de sulfonilureas