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ES475509A1 - Un metodo de preparacion de una vacuna polivalente eficaz contra el streptococcus pneumoniae que comprende polisacari-dos capsulares altamente purificados de estreptococcus pneu-moniae. - Google Patents

Un metodo de preparacion de una vacuna polivalente eficaz contra el streptococcus pneumoniae que comprende polisacari-dos capsulares altamente purificados de estreptococcus pneu-moniae.

Info

Publication number
ES475509A1
ES475509A1 ES475509A ES475509A ES475509A1 ES 475509 A1 ES475509 A1 ES 475509A1 ES 475509 A ES475509 A ES 475509A ES 475509 A ES475509 A ES 475509A ES 475509 A1 ES475509 A1 ES 475509A1
Authority
ES
Spain
Prior art keywords
preparation
pneumococcal vaccine
streptococcus pneumoniae
proteins
followed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES475509A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of ES475509A1 publication Critical patent/ES475509A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

1. Esta invención proporciona una vacuna eficaz contra uno o más tipos de strepcoccus pneumoniae, que comprende uno o más polisacáridos capsulares altamente purificados de Streptococcus pneumoniae. Cada polisacárido capsular se prepara cultivando el organismo productos de ese polisacárido capsular, en condiciones controladas de pH y reponiendo la concentración de glucosa durante la fermentación.
ES475509A 1977-11-28 1978-11-28 Un metodo de preparacion de una vacuna polivalente eficaz contra el streptococcus pneumoniae que comprende polisacari-dos capsulares altamente purificados de estreptococcus pneu-moniae. Expired ES475509A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US85549177A 1977-11-28 1977-11-28

Publications (1)

Publication Number Publication Date
ES475509A1 true ES475509A1 (es) 1980-07-16

Family

ID=25321387

Family Applications (1)

Application Number Title Priority Date Filing Date
ES475509A Expired ES475509A1 (es) 1977-11-28 1978-11-28 Un metodo de preparacion de una vacuna polivalente eficaz contra el streptococcus pneumoniae que comprende polisacari-dos capsulares altamente purificados de estreptococcus pneu-moniae.

Country Status (13)

Country Link
EP (1) EP0002404A1 (es)
JP (1) JPS5495724A (es)
AU (1) AU529128B2 (es)
CA (1) CA1115210A (es)
DK (1) DK527078A (es)
ES (1) ES475509A1 (es)
FI (1) FI783620A (es)
IT (1) IT1109450B (es)
NO (1) NO783976L (es)
NZ (1) NZ188966A (es)
PT (1) PT68831A (es)
YU (1) YU283378A (es)
ZA (1) ZA786664B (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4242501A (en) * 1979-08-08 1980-12-30 American Cyanamid Company Purification of pneumococcal capsular polysaccharides
US4287173A (en) * 1979-09-24 1981-09-01 Merck & Co., Inc. Vaccine for dental caries
FR2510606A1 (fr) * 1981-07-30 1983-02-04 Berri Balzac Procede d'obtention de polyosides capsulaires, polyosides capsulaires ainsi obtenus et leur application a la preparation de vaccins
BE889979A (fr) * 1981-08-14 1982-02-15 Smith Kline Rit Procede de preparation de polysaccharides bacteriens capsulaires antigeniques purifies, produits obtenus et leur utilisation
NL8202527A (nl) * 1982-06-22 1984-01-16 Univ Utrecht Vaccins tegen door bacterien met kapsel-polysacchariden verwekte ziekten en werkwijze voor het bereiden daarvan.
US4686102A (en) * 1984-04-12 1987-08-11 American Cyanamid Company Multivalent pneumococcal vaccine and preparation thereof
NZ214503A (en) * 1984-12-20 1990-02-26 Merck & Co Inc Covalently-modified neutral bacterial polysaccharides, stable covalent conjugates of such polysaccharides and immunogenic proteins, and methods of preparing such polysaccharides and conjugates
US5714354A (en) * 1995-06-06 1998-02-03 American Home Products Corporation Alcohol-free pneumococcal polysaccharide purification process
US6224880B1 (en) 1997-09-24 2001-05-01 Merck & Co., Inc. Immunization against Streptococcus pneumoniae using conjugated and unconjugated pneumoccocal polysaccharide vaccines
CN104815327A (zh) 2005-04-08 2015-08-05 惠氏有限责任公司 多价肺炎球菌多糖-蛋白质缀合物组合物
SI1866342T1 (sl) * 2005-04-08 2019-02-28 Wyeth Llc Ločevanje onesnaževalcev od polisaharida streptococcus pneumoniae s postopkom manipulacije pH
PT3406635T (pt) * 2007-03-23 2022-07-08 Wyeth Llc Processo de purificação abreviado para a produção de polissacáridos capsulares de streptococcus pneumoniae
HUE037465T2 (hu) 2008-12-18 2018-09-28 Wyeth Llc Eljárás 19A szerotípusú streptococcus pneumoniae poliszacharidok molekulatömegének szabályozására
RU2524436C2 (ru) 2008-12-18 2014-07-27 УАЙТ ЭлЭлСи Способ получения жидкой фракции, содержащей изолированные высокомолекулярные капсульные полисахариды streptococcus pneumoniae, и жидкая фракция, полученная таким способом
EP2705141A1 (en) * 2011-05-02 2014-03-12 FrieslandBrands B.V. Probiotics with enhanced survival properties
CN106460062A (zh) 2014-05-05 2017-02-22 美敦力公司 用于scd、crt、crt‑d或sca治疗识别和/或选择的方法和组合物
CN114853917A (zh) * 2022-04-22 2022-08-05 兰州生物制品研究所有限责任公司 制备肺炎球菌荚膜多糖和肺炎球菌疫苗的方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2388563A1 (fr) * 1977-04-29 1978-11-24 Fabre Sa Pierre Vaccins acellulaires perfectionnes contenant des polysaccharides capsulaires

Also Published As

Publication number Publication date
AU4172878A (en) 1979-06-07
FI783620A (fi) 1979-05-29
IT7852075A0 (it) 1978-11-27
NO783976L (no) 1979-05-29
ZA786664B (en) 1980-07-30
YU283378A (en) 1983-04-30
NZ188966A (en) 1982-03-23
CA1115210A (en) 1981-12-29
PT68831A (en) 1978-12-01
DK527078A (da) 1979-07-04
EP0002404A1 (en) 1979-06-13
IT1109450B (it) 1985-12-16
JPS5495724A (en) 1979-07-28
AU529128B2 (en) 1983-05-26

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