ES475122A1 - A PROCEDURE FOR THE PREPARATION OF NEW DERIVATIVES OF 4-AMINO-2-PIPERIDINE-QUINAZOLINA. - Google Patents
A PROCEDURE FOR THE PREPARATION OF NEW DERIVATIVES OF 4-AMINO-2-PIPERIDINE-QUINAZOLINA.Info
- Publication number
- ES475122A1 ES475122A1 ES475122A ES475122A ES475122A1 ES 475122 A1 ES475122 A1 ES 475122A1 ES 475122 A ES475122 A ES 475122A ES 475122 A ES475122 A ES 475122A ES 475122 A1 ES475122 A1 ES 475122A1
- Authority
- ES
- Spain
- Prior art keywords
- lower alkyl
- amino
- procedure
- preparation
- quinazolina
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 150000002431 hydrogen Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 abstract 1
- MDGLKMXWHKGENE-UHFFFAOYSA-N 2-piperidin-1-ylquinazolin-4-amine Chemical class N=1C2=CC=CC=C2C(N)=NC=1N1CCCCC1 MDGLKMXWHKGENE-UHFFFAOYSA-N 0.000 abstract 1
- 125000000816 ethylene group Chemical group [H]C([H])([*:1])C([H])([H])[*:2] 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Landscapes
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
A procedure for the preparation of new 4-amino-2-piperidino-quinazoline derivatives of formula: *** see image 01 where R is lower alkyl and, X is a group of formula: -O-alq-OR1 where "alq "represents an ethylene group optionally substituted with one or two lower alkyl groups and R1 is hydrogen, lower alkyl, C3-C6 cycloalkyl or a group of formula: *** see image 02 where R2 and R3 each independently represent hydrogen, lower alkyl, halogen, CF3, -CONR4R5 or SO2NR4R5. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB4758377 | 1977-11-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES475122A1 true ES475122A1 (en) | 1979-05-16 |
Family
ID=10445508
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES475122A Expired ES475122A1 (en) | 1977-11-16 | 1978-11-15 | A PROCEDURE FOR THE PREPARATION OF NEW DERIVATIVES OF 4-AMINO-2-PIPERIDINE-QUINAZOLINA. |
Country Status (16)
| Country | Link |
|---|---|
| AR (1) | AR219773A1 (en) |
| DD (1) | DD140145A5 (en) |
| DK (1) | DK440378A (en) |
| ES (1) | ES475122A1 (en) |
| FI (1) | FI63935C (en) |
| GR (1) | GR72239B (en) |
| IE (1) | IE47510B1 (en) |
| IL (1) | IL55934A (en) |
| IT (1) | IT1101414B (en) |
| NO (1) | NO783829L (en) |
| NZ (1) | NZ188915A (en) |
| PH (1) | PH13927A (en) |
| PL (1) | PL112638B1 (en) |
| PT (1) | PT68784A (en) |
| YU (1) | YU263878A (en) |
| ZA (1) | ZA786423B (en) |
-
1978
- 1978-10-04 DK DK440378A patent/DK440378A/en not_active Application Discontinuation
- 1978-10-30 PH PH21753A patent/PH13927A/en unknown
- 1978-11-14 AR AR27442578A patent/AR219773A1/en active
- 1978-11-14 FI FI783477A patent/FI63935C/en not_active IP Right Cessation
- 1978-11-14 NO NO783829A patent/NO783829L/en unknown
- 1978-11-14 PT PT6878478A patent/PT68784A/en unknown
- 1978-11-14 IT IT29773/78A patent/IT1101414B/en active
- 1978-11-14 YU YU263878A patent/YU263878A/en unknown
- 1978-11-14 IL IL55934A patent/IL55934A/en unknown
- 1978-11-14 NZ NZ18891578A patent/NZ188915A/en unknown
- 1978-11-15 ES ES475122A patent/ES475122A1/en not_active Expired
- 1978-11-15 IE IE225478A patent/IE47510B1/en unknown
- 1978-11-15 ZA ZA00786423A patent/ZA786423B/en unknown
- 1978-11-15 GR GR57654A patent/GR72239B/el unknown
- 1978-11-16 DD DD20913378A patent/DD140145A5/en unknown
- 1978-11-16 PL PL21098278A patent/PL112638B1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IE782254L (en) | 1979-05-16 |
| PH13927A (en) | 1980-11-04 |
| PL210982A1 (en) | 1979-06-18 |
| PT68784A (en) | 1978-12-01 |
| NO783829L (en) | 1979-05-18 |
| IT1101414B (en) | 1985-09-28 |
| DD140145A5 (en) | 1980-02-13 |
| AR219773A1 (en) | 1980-09-15 |
| DK440378A (en) | 1979-05-17 |
| YU263878A (en) | 1982-08-31 |
| FI783477A (en) | 1979-05-17 |
| IT7829773A0 (en) | 1978-11-14 |
| NZ188915A (en) | 1980-08-26 |
| PL112638B1 (en) | 1980-10-31 |
| FI63935B (en) | 1983-05-31 |
| ZA786423B (en) | 1979-10-31 |
| GR72239B (en) | 1983-10-03 |
| FI63935C (en) | 1983-09-12 |
| IL55934A (en) | 1982-08-31 |
| IE47510B1 (en) | 1984-04-04 |
| IL55934A0 (en) | 1979-01-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19980202 |