ES469749A1 - A PROCEDURE FOR THE PREPARATION OF A PHARMACEUTICAL FORMULATION OF A NOTROIMIDAZOLE DRUG. - Google Patents
A PROCEDURE FOR THE PREPARATION OF A PHARMACEUTICAL FORMULATION OF A NOTROIMIDAZOLE DRUG.Info
- Publication number
- ES469749A1 ES469749A1 ES469749A ES469749A ES469749A1 ES 469749 A1 ES469749 A1 ES 469749A1 ES 469749 A ES469749 A ES 469749A ES 469749 A ES469749 A ES 469749A ES 469749 A1 ES469749 A1 ES 469749A1
- Authority
- ES
- Spain
- Prior art keywords
- preparation
- pharmaceutical formulation
- drug
- notroimidazole
- procedure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000003814 drug Substances 0.000 title abstract 3
- 229940079593 drug Drugs 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- YZEUHQHUFTYLPH-UHFFFAOYSA-N 2-nitroimidazole Chemical compound [O-][N+](=O)C1=NC=CN1 YZEUHQHUFTYLPH-UHFFFAOYSA-N 0.000 abstract 2
- GLDQAMYCGOIJDV-UHFFFAOYSA-N Pyrocatechuic acid Natural products OC(=O)C1=CC=CC(O)=C1O GLDQAMYCGOIJDV-UHFFFAOYSA-N 0.000 abstract 2
- 239000007864 aqueous solution Substances 0.000 abstract 1
- -1 di-hydroxybenzyl Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
A process for the preparation of a pharmaceutical formulation of a nitroimidazole drug consisting of treating the nitroimidazole drug with an aqueous solution of a pharmaceutically acceptable salt of a mono- or di-hydroxybenzoic acid or of a mono- or di-hydroxybenzyl alcohol, sterilize and, if desired, lyophilize the resulting solution. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB2037977 | 1977-05-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES469749A1 true ES469749A1 (en) | 1978-12-16 |
Family
ID=10144988
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES469749A Expired ES469749A1 (en) | 1977-05-14 | 1978-05-11 | A PROCEDURE FOR THE PREPARATION OF A PHARMACEUTICAL FORMULATION OF A NOTROIMIDAZOLE DRUG. |
Country Status (16)
Country | Link |
---|---|
JP (1) | JPS542315A (en) |
AU (1) | AU504551B1 (en) |
BE (1) | BE867040A (en) |
DE (1) | DE2820992A1 (en) |
DK (1) | DK212678A (en) |
ES (1) | ES469749A1 (en) |
FI (1) | FI781507A (en) |
FR (1) | FR2390162A1 (en) |
IL (1) | IL54687A0 (en) |
IT (1) | IT1115599B (en) |
LU (1) | LU79655A1 (en) |
NL (1) | NL7805158A (en) |
NO (1) | NO781688L (en) |
PT (1) | PT68034B (en) |
SE (1) | SE7805471L (en) |
ZA (1) | ZA782736B (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0024023B2 (en) * | 1979-08-11 | 1992-11-11 | Bayer Ag | Antimycotic agents with enhanced release of the active ingredients |
FR2624736B1 (en) * | 1987-12-16 | 1991-03-22 | Dietlin Francois | NEW WATER-DISPERSIBLE PHARMACEUTICAL COMPOSITIONS BASED ON ORNIDAZOLE |
CN104127379A (en) * | 2014-08-14 | 2014-11-05 | 珠海亿邦制药股份有限公司 | Ornidazole injection and preparation method thereof |
CN110538144A (en) * | 2019-06-13 | 2019-12-06 | 南京瓦尔生物医药有限公司 | Ornidazole injection and S-ornidazole injection |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4032645A (en) * | 1975-06-19 | 1977-06-28 | G. D. Searle & Co. | Injectable metronidazole composition |
-
1978
- 1978-05-10 IL IL54687A patent/IL54687A0/en unknown
- 1978-05-11 ES ES469749A patent/ES469749A1/en not_active Expired
- 1978-05-12 NO NO78781688A patent/NO781688L/en unknown
- 1978-05-12 PT PT68034A patent/PT68034B/en unknown
- 1978-05-12 IT IT23351/78A patent/IT1115599B/en active
- 1978-05-12 FR FR7814291A patent/FR2390162A1/en not_active Withdrawn
- 1978-05-12 DK DK212678A patent/DK212678A/en not_active Application Discontinuation
- 1978-05-12 SE SE7805471A patent/SE7805471L/en unknown
- 1978-05-12 AU AU36078/78A patent/AU504551B1/en not_active Expired
- 1978-05-12 BE BE187664A patent/BE867040A/en unknown
- 1978-05-12 ZA ZA00782736A patent/ZA782736B/en unknown
- 1978-05-12 FI FI781507A patent/FI781507A/en not_active Application Discontinuation
- 1978-05-12 LU LU79655A patent/LU79655A1/en unknown
- 1978-05-12 DE DE19782820992 patent/DE2820992A1/en active Pending
- 1978-05-12 NL NL7805158A patent/NL7805158A/en not_active Application Discontinuation
- 1978-05-13 JP JP5706378A patent/JPS542315A/en active Pending
Also Published As
Publication number | Publication date |
---|---|
IT1115599B (en) | 1986-02-03 |
IL54687A0 (en) | 1978-07-31 |
NL7805158A (en) | 1978-11-16 |
JPS542315A (en) | 1979-01-09 |
AU504551B1 (en) | 1979-10-18 |
NO781688L (en) | 1978-11-15 |
PT68034A (en) | 1978-06-01 |
FI781507A (en) | 1978-11-15 |
SE7805471L (en) | 1978-11-15 |
PT68034B (en) | 1979-10-24 |
ZA782736B (en) | 1979-05-30 |
FR2390162A1 (en) | 1978-12-08 |
IT7823351A0 (en) | 1978-05-12 |
DK212678A (en) | 1978-11-15 |
LU79655A1 (en) | 1979-12-06 |
DE2820992A1 (en) | 1978-12-07 |
BE867040A (en) | 1978-11-13 |
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