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ES469164A1 - 2-benzylperhydroazepines process for their preparation and pharmaceutical compositions containing them - Google Patents

2-benzylperhydroazepines process for their preparation and pharmaceutical compositions containing them

Info

Publication number
ES469164A1
ES469164A1 ES469164A ES469164A ES469164A1 ES 469164 A1 ES469164 A1 ES 469164A1 ES 469164 A ES469164 A ES 469164A ES 469164 A ES469164 A ES 469164A ES 469164 A1 ES469164 A1 ES 469164A1
Authority
ES
Spain
Prior art keywords
group
preparation
benzylperhydroazepines
pharmaceutical compositions
compositions containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES469164A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda GmbH
Original Assignee
Byk Gulden Lomberg Chemische Fabrik GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from LU77229A external-priority patent/LU77229A1/xx
Application filed by Byk Gulden Lomberg Chemische Fabrik GmbH filed Critical Byk Gulden Lomberg Chemische Fabrik GmbH
Publication of ES469164A1 publication Critical patent/ES469164A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D223/08—Oxygen atoms
    • C07D223/10—Oxygen atoms attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/04—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with only hydrogen atoms, halogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D223/12—Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Process for the preparation of 2-benzylperhydroazapine of the general formula I ** (Formula) ** where R1 signifies a hydrogen atom, an aliphatic or alicyclic hydrocarbon radical, a cycloalkoxylalkyl group or an aralcoyl group; R2, R3, R4 and R5 are the same or different, and signify a hydrogen atom, a halogen atom, an alcohol group, a hydroxy group, an alkoxy group, an acyloxy group, an optionally substituted amino group, a nitro phenyl group possibly substituted, R1 not being methyl when R2, R3, R4 and R5 have the meanings of hydrogen, and their salts by addition of acid. (Machine-translation by Google Translate, not legally binding)
ES469164A 1977-04-29 1978-04-26 2-benzylperhydroazepines process for their preparation and pharmaceutical compositions containing them Expired ES469164A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
LU77229A LU77229A1 (en) 1977-04-29 1977-04-29
DK339777A DK339777A (en) 1977-04-29 1977-07-27 PROCEDURE FOR THE PREPARATION OF 2-BENZYLPERHYDROAZEPINES

Publications (1)

Publication Number Publication Date
ES469164A1 true ES469164A1 (en) 1979-09-16

Family

ID=26067032

Family Applications (1)

Application Number Title Priority Date Filing Date
ES469164A Expired ES469164A1 (en) 1977-04-29 1978-04-26 2-benzylperhydroazepines process for their preparation and pharmaceutical compositions containing them

Country Status (16)

Country Link
JP (1) JPS53135994A (en)
AU (1) AU525198B2 (en)
CA (1) CA1114374A (en)
DE (1) DE2818995A1 (en)
ES (1) ES469164A1 (en)
FI (1) FI781338A (en)
FR (1) FR2388797A1 (en)
GB (1) GB1593223A (en)
GR (1) GR62674B (en)
IE (1) IE46629B1 (en)
IL (1) IL54588A (en)
IT (1) IT1094972B (en)
NL (1) NL7804579A (en)
NO (1) NO781530L (en)
NZ (1) NZ187108A (en)
PT (1) PT67966B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5013759A (en) * 1985-06-10 1991-05-07 The Procter & Gamble Company Compounds and compositions having anti-inflammatory and analgesic activity

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1466307A (en) * 1964-08-18 1967-01-20 Thomae Gmbh Dr K Process for preparing novel substituted aminoketones

Also Published As

Publication number Publication date
AU525198B2 (en) 1982-10-28
PT67966A (en) 1978-05-01
FR2388797A1 (en) 1978-11-24
NO781530L (en) 1978-10-31
DE2818995A1 (en) 1978-11-02
PT67966B (en) 1979-11-14
FR2388797B1 (en) 1980-10-31
NL7804579A (en) 1978-10-31
IT7822842A0 (en) 1978-04-28
FI781338A (en) 1978-10-30
IL54588A (en) 1982-05-31
JPS53135994A (en) 1978-11-28
IE46629B1 (en) 1983-08-10
GR62674B (en) 1979-05-22
GB1593223A (en) 1981-07-15
IL54588A0 (en) 1978-07-31
NZ187108A (en) 1979-12-11
AU3555178A (en) 1979-11-01
CA1114374A (en) 1981-12-15
IT1094972B (en) 1985-08-10
IE780851L (en) 1978-10-29

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19971001