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ES461326A1 - Un procedimiento para la preparacion de d-homoesteroides. - Google Patents

Un procedimiento para la preparacion de d-homoesteroides.

Info

Publication number
ES461326A1
ES461326A1 ES461326A ES461326A ES461326A1 ES 461326 A1 ES461326 A1 ES 461326A1 ES 461326 A ES461326 A ES 461326A ES 461326 A ES461326 A ES 461326A ES 461326 A1 ES461326 A1 ES 461326A1
Authority
ES
Spain
Prior art keywords
hydrogen atom
homosteroids
preparation
procedure
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES461326A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
HOFFMANN LA ROCHE
F Hoffmann La Roche AG
Original Assignee
HOFFMANN LA ROCHE
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH1456475A external-priority patent/CH616436A5/de
Application filed by HOFFMANN LA ROCHE, F Hoffmann La Roche AG filed Critical HOFFMANN LA ROCHE
Publication of ES461326A1 publication Critical patent/ES461326A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J21/00Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/005Ketals
    • C07J21/006Ketals at position 3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J21/00Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0038Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 with an androstane skeleton, including 18- or 19-substituted derivatives, 18-nor derivatives and also derivatives where position 17-beta is substituted by a carbon atom not directly bonded to a further carbon atom and not being part of an amide group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J63/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/008Expansion of ring D by one atom, e.g. D homo steroids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Un procedimiento para la preparación de D- homoesteroides de la fórmula general **(Fórmula)** en donde una de las líneas de trazos en el anillo A designa un enlace e carbono-carbono; R1 representa un átomo de hidrógeno o un grupo de metilo; R7 representa un átomo de hidrógeno o un grupo de metilo; R17aBeta representa un átomo de hidrógeno o un grupo de alquilo de C1-C10, bencilo, ciclohexilmetilo, acilo, tetrahidropiranilo o cicloalquenilo y R17aAlfa representa un átomo de hidrógeno o un grupo de alquilo inferior, etinilo, vinilo o propadienilo.
ES461326A 1975-11-11 1977-08-03 Un procedimiento para la preparacion de d-homoesteroides. Expired ES461326A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH1456475A CH616436A5 (en) 1975-11-11 1975-11-11 Process for the preparation of D-homosteroids.
CH1160476 1976-09-13

Publications (1)

Publication Number Publication Date
ES461326A1 true ES461326A1 (es) 1978-12-01

Family

ID=25708627

Family Applications (2)

Application Number Title Priority Date Filing Date
ES461325A Expired ES461325A1 (es) 1975-11-11 1977-08-03 Un procedimiento para la preparacion de d-homoesteroides.
ES461326A Expired ES461326A1 (es) 1975-11-11 1977-08-03 Un procedimiento para la preparacion de d-homoesteroides.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES461325A Expired ES461325A1 (es) 1975-11-11 1977-08-03 Un procedimiento para la preparacion de d-homoesteroides.

Country Status (20)

Country Link
JP (1) JPS5259148A (es)
AT (1) AT354653B (es)
AU (1) AU505624B2 (es)
CA (1) CA1082686A (es)
DD (1) DD128852A5 (es)
DE (1) DE2651364A1 (es)
ES (2) ES461325A1 (es)
FR (1) FR2331329A1 (es)
GB (1) GB1564144A (es)
GR (1) GR70298B (es)
IE (1) IE43985B1 (es)
IL (1) IL50854A (es)
LU (1) LU76161A1 (es)
MC (1) MC1121A1 (es)
NL (1) NL7612538A (es)
NZ (1) NZ182539A (es)
PH (1) PH13603A (es)
PL (1) PL193604A1 (es)
PT (1) PT65821B (es)
SU (1) SU679147A3 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4788218A (en) * 1984-05-21 1988-11-29 Sri International 17 a β-hydroxy-7 α-methyl-d-homo-19-norandrost-4,16-diene-3-one and the 17-esters thereof: methods of preparation and uses
GB2362648A (en) * 2000-05-23 2001-11-28 Univerzita Palackeho V Olomouc Triterpenoid derivatives
WO2005021573A1 (de) * 2003-08-21 2005-03-10 Schering Ag Δ15-d-homosteroide mit androgener wirkung

Also Published As

Publication number Publication date
NL7612538A (nl) 1977-05-13
FR2331329B1 (es) 1981-11-27
FR2331329A1 (fr) 1977-06-10
IE43985B1 (en) 1981-07-15
DD128852A5 (de) 1977-12-14
ATA834476A (de) 1979-06-15
GR70298B (es) 1982-09-06
CA1082686A (en) 1980-07-29
IE43985L (en) 1977-05-11
PH13603A (en) 1980-08-05
AU505624B2 (en) 1979-11-29
GB1564144A (en) 1980-04-02
MC1121A1 (fr) 1977-08-12
SU679147A3 (ru) 1979-08-05
AT354653B (de) 1979-01-25
AU1943176A (en) 1978-05-18
PL193604A1 (pl) 1979-03-26
DE2651364A1 (de) 1977-05-12
ES461325A1 (es) 1978-12-16
PT65821B (en) 1978-10-10
IL50854A (en) 1979-12-30
PT65821A (en) 1976-12-01
IL50854A0 (en) 1977-01-31
LU76161A1 (es) 1977-12-13
NZ182539A (en) 1979-07-11
JPS5259148A (en) 1977-05-16

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