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ES458237A1 - Derivatives of 2-imino-4-thiazolines and thiazolidines - Google Patents

Derivatives of 2-imino-4-thiazolines and thiazolidines

Info

Publication number
ES458237A1
ES458237A1 ES458237A ES458237A ES458237A1 ES 458237 A1 ES458237 A1 ES 458237A1 ES 458237 A ES458237 A ES 458237A ES 458237 A ES458237 A ES 458237A ES 458237 A1 ES458237 A1 ES 458237A1
Authority
ES
Spain
Prior art keywords
imino
thiazolines
thiazolidines
derivatives
novel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES458237A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of ES458237A1 publication Critical patent/ES458237A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/18—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/39—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by esterified hydroxy groups
    • C07C205/42—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by esterified hydroxy groups having nitro groups or esterified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C205/43—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by esterified hydroxy groups having nitro groups or esterified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/16—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

The novel N,N'-bis-(3-methylthiazolidin-2-ylidene)succinamide of the formula < IMAGE > is prepared. This compound is obtained by reacting 2-imino-3-methylthiazolidine either with 3-methyl-2-succinyliminothiazolidine in the presence of ethyl chloroformate or with a derivative of succinic acid. The novel compound can be used for treating mental disturbances.
ES458237A 1976-05-03 1977-04-27 Derivatives of 2-imino-4-thiazolines and thiazolidines Expired ES458237A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US68287676A 1976-05-03 1976-05-03

Publications (1)

Publication Number Publication Date
ES458237A1 true ES458237A1 (en) 1978-07-01

Family

ID=24741558

Family Applications (2)

Application Number Title Priority Date Filing Date
ES458237A Expired ES458237A1 (en) 1976-05-03 1977-04-27 Derivatives of 2-imino-4-thiazolines and thiazolidines
ES468377A Expired ES468377A1 (en) 1976-05-03 1978-03-30 Derivatives of 2-imino-4-thiazolines and thiazolidines

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES468377A Expired ES468377A1 (en) 1976-05-03 1978-03-30 Derivatives of 2-imino-4-thiazolines and thiazolidines

Country Status (24)

Country Link
JP (1) JPS52133981A (en)
AU (1) AU508889B2 (en)
BE (1) BE854172A (en)
CA (1) CA1078846A (en)
CH (1) CH629490A5 (en)
DE (1) DE2719577A1 (en)
DK (1) DK173777A (en)
ES (2) ES458237A1 (en)
FI (1) FI771285A (en)
FR (1) FR2350351A1 (en)
GB (1) GB1534242A (en)
HU (1) HU180504B (en)
IE (1) IE46011B1 (en)
IL (1) IL51935A (en)
IT (1) IT1082657B (en)
LU (1) LU77243A1 (en)
NL (1) NL7704322A (en)
NO (1) NO146061C (en)
NZ (1) NZ183941A (en)
PH (1) PH14030A (en)
PL (1) PL123449B1 (en)
SE (1) SE7704594L (en)
YU (1) YU111677A (en)
ZA (1) ZA772614B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU188852B (en) * 1983-03-16 1986-05-28 Richter Gedeon Vegyeszeti Gyar Rt,Hu Process for producing thiazolidine derivatives active against gastric ulcer and intestinal ulcer
US5555162A (en) * 1994-04-26 1996-09-10 Sylvan R. Shemitz Designs, Inc. Compact fluorescent luminaire
USRE37310E1 (en) 1994-12-06 2001-08-07 Sylvan R. Shemitz Designs, Inc. Compact fluorescent luminaire
FR2748023B1 (en) * 1996-04-30 1998-07-24 Rhone Poulenc Chimie HYDROGENOFLUOROSULFONATES OF ORGANIC BASIS, THEIR USE TO RELEASE ORGANIC BASES FROM THEIR FLUORHYDRATE, THEIR PREPARATION PROCESS, COMPOSITIONS CONTAINING THEM

Also Published As

Publication number Publication date
PL123449B1 (en) 1982-10-30
PH14030A (en) 1980-12-12
CA1078846A (en) 1980-06-03
IT1082657B (en) 1985-05-21
AU508889B2 (en) 1980-04-03
NL7704322A (en) 1977-11-07
BE854172A (en) 1977-11-03
FR2350351A1 (en) 1977-12-02
YU111677A (en) 1983-01-21
HU180504B (en) 1983-03-28
NO146061B (en) 1982-04-13
FI771285A (en) 1977-11-04
GB1534242A (en) 1978-11-29
SE7704594L (en) 1977-11-04
IE46011L (en) 1977-11-03
CH629490A5 (en) 1982-04-30
DK173777A (en) 1977-11-04
LU77243A1 (en) 1977-12-13
IE46011B1 (en) 1983-01-26
NZ183941A (en) 1980-12-19
FR2350351B1 (en) 1979-03-02
ZA772614B (en) 1978-12-27
IL51935A0 (en) 1977-06-30
NO771375L (en) 1977-11-04
AU2463077A (en) 1978-11-02
ES468377A1 (en) 1978-12-16
DE2719577A1 (en) 1977-11-24
IL51935A (en) 1981-07-31
NO146061C (en) 1982-07-28
JPS52133981A (en) 1977-11-09

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19980202