ES457227A1 - Procedimiento para la preparacion de nuevos derivados ciclo-hexilfenilicos. - Google Patents
Procedimiento para la preparacion de nuevos derivados ciclo-hexilfenilicos.Info
- Publication number
- ES457227A1 ES457227A1 ES457227A ES457227A ES457227A1 ES 457227 A1 ES457227 A1 ES 457227A1 ES 457227 A ES457227 A ES 457227A ES 457227 A ES457227 A ES 457227A ES 457227 A1 ES457227 A1 ES 457227A1
- Authority
- ES
- Spain
- Prior art keywords
- group
- carbon atoms
- cyclohexylphenyl
- ethane
- sulfur
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- HNBJZFPJDFJMLP-UHFFFAOYSA-N 1-cyclohexylethylbenzene Chemical class C=1C=CC=CC=1C(C)C1CCCCC1 HNBJZFPJDFJMLP-UHFFFAOYSA-N 0.000 title 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 title 1
- 229910052717 sulfur Inorganic materials 0.000 title 1
- 239000011593 sulfur Substances 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000003158 alcohol group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 abstract 1
- -1 cyclohexylphenyl Chemical class 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004573 morpholin-4-yl group Chemical group N1(CCOCC1)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/52—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Hematology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Procedimiento para la preparación de nuevos derivados ciclohexilfenílicos de la fórmula general I, *** ver imagen 01 en la que R1, significa un átomo de hidrógeno o de halógeno, R2 significa un grupo alcoxi con 1 a 6 átomos de carbono, un grupo aralcoxi con 7 a 10 átomos de carbono, un grupo amino eventualmente sustituido con un grupo alcohilo con 1 a 3 átomos de carbono, el grupo piparidino o morfolino; y n significa los números 0, 1 ó 2, y de sus diastereoisómeros, caracterizado porque se hace reaccionar un ácido carboxílico de la fórmula general II *** ver imagen 02
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2546319A DE2546319C2 (de) | 1975-10-16 | 1975-10-16 | Cyclohexylphenyl-Derivate, Verfahren zu deren Herstellung und diese enthaltende Mittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES457227A1 true ES457227A1 (es) | 1978-02-01 |
Family
ID=5959276
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES451710A Expired ES451710A1 (es) | 1975-10-16 | 1976-09-21 | Procedimiento para la preparacion de nuevos derivados ciclo-hexilfenilicos. |
| ES457227A Expired ES457227A1 (es) | 1975-10-16 | 1977-03-25 | Procedimiento para la preparacion de nuevos derivados ciclo-hexilfenilicos. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES451710A Expired ES451710A1 (es) | 1975-10-16 | 1976-09-21 | Procedimiento para la preparacion de nuevos derivados ciclo-hexilfenilicos. |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US4062973A (es) |
| JP (1) | JPS6016412B2 (es) |
| AT (1) | AT344150B (es) |
| AU (1) | AU507034B2 (es) |
| BE (1) | BE847373A (es) |
| CH (3) | CH622777A5 (es) |
| DE (1) | DE2546319C2 (es) |
| DK (1) | DK153942C (es) |
| ES (2) | ES451710A1 (es) |
| FI (1) | FI62066C (es) |
| FR (1) | FR2327767A1 (es) |
| GB (1) | GB1524637A (es) |
| HK (1) | HK16582A (es) |
| IE (1) | IE44177B1 (es) |
| KE (1) | KE3177A (es) |
| LU (1) | LU76009A1 (es) |
| MY (1) | MY8200196A (es) |
| NL (1) | NL180563C (es) |
| NO (1) | NO142524C (es) |
| SE (1) | SE433210B (es) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1584462A (en) * | 1977-03-31 | 1981-02-11 | Lafon Labor | N-diaryl-malonamide and diarylmethyl-sulphinyl-acetamide derivatives and pharmaceutical compositions containing them |
| FR2528041A1 (fr) * | 1982-06-04 | 1983-12-09 | Lafon Labor | Acides halogenobenzhydrylsulfinylacetohydroxamiques, procede de preparation et utilisation en therapeutique |
| US5256692A (en) * | 1992-01-07 | 1993-10-26 | E. R. Squibb & Sons, Inc. | Sulfur-containing HMG-COA reductase inhibitors |
| US6362183B1 (en) | 1997-03-04 | 2002-03-26 | G. D. Searle & Company | Aromatic sulfonyl alpha-hydroxy hydroxamic acid compounds |
| ITMI20020991A1 (it) * | 2002-05-10 | 2003-11-10 | Dinamite Dipharma S P A In For | Procedimento per la sintesi del modafinil |
| US7449481B2 (en) * | 2004-04-13 | 2008-11-11 | Cephalon, Inc. | Thio-substituted biaryl-methanesulfinyl derivatives |
| CN112919984B (zh) * | 2021-04-16 | 2022-03-08 | 安徽硒无忧现代农业科技有限公司 | 一种生态化富硒有机营养液及其制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1532701A (fr) * | 1966-06-23 | 1968-07-12 | Ici Ltd | Nouveaux dérivés aryliques d'acides carboxyliques |
| GB1121027A (en) * | 1966-06-23 | 1968-07-24 | Ici Ltd | New carboxylic acid derivatives, processes for the preparation thereof and compositions containing the same |
| US4000183A (en) * | 1972-11-01 | 1976-12-28 | Ciba-Geigy Corporation | Adamantyl-phenoxy- and phenylthio-alkyl-alkanoyl esters |
| DK422774A (es) * | 1973-09-18 | 1975-05-20 | Ciba Geigy Ag | |
| AT336589B (de) * | 1974-05-20 | 1977-05-10 | Thomae Gmbh Dr K | Verfahren zur herstellung von neuen biphenylderivaten |
-
1975
- 1975-10-16 DE DE2546319A patent/DE2546319C2/de not_active Expired
-
1976
- 1976-09-21 ES ES451710A patent/ES451710A1/es not_active Expired
- 1976-09-28 AT AT717076A patent/AT344150B/de not_active IP Right Cessation
- 1976-09-29 DK DK438976A patent/DK153942C/da not_active IP Right Cessation
- 1976-09-30 FI FI762785A patent/FI62066C/fi not_active IP Right Cessation
- 1976-10-06 US US05/730,122 patent/US4062973A/en not_active Expired - Lifetime
- 1976-10-12 NL NLAANVRAGE7611254,A patent/NL180563C/xx active Search and Examination
- 1976-10-14 LU LU76009A patent/LU76009A1/xx unknown
- 1976-10-14 CH CH1302676A patent/CH622777A5/de not_active IP Right Cessation
- 1976-10-14 IE IE2267/76A patent/IE44177B1/en unknown
- 1976-10-15 BE BE171583A patent/BE847373A/xx not_active IP Right Cessation
- 1976-10-15 SE SE7611494A patent/SE433210B/xx not_active IP Right Cessation
- 1976-10-15 NO NO763532A patent/NO142524C/no unknown
- 1976-10-15 GB GB43008/76A patent/GB1524637A/en not_active Expired
- 1976-10-15 JP JP51123769A patent/JPS6016412B2/ja not_active Expired
- 1976-10-15 FR FR7631122A patent/FR2327767A1/fr active Granted
- 1976-10-15 AU AU18738/76A patent/AU507034B2/en not_active Expired
-
1977
- 1977-03-25 ES ES457227A patent/ES457227A1/es not_active Expired
-
1980
- 1980-10-14 CH CH766180A patent/CH625210A5/de not_active IP Right Cessation
- 1980-10-14 CH CH766080A patent/CH624099A5/de not_active IP Right Cessation
-
1981
- 1981-12-11 KE KE3177A patent/KE3177A/xx unknown
-
1982
- 1982-04-08 HK HK165/82A patent/HK16582A/xx unknown
- 1982-12-30 MY MY196/82A patent/MY8200196A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AT344150B (de) | 1978-07-10 |
| US4062973A (en) | 1977-12-13 |
| DK153942C (da) | 1989-02-13 |
| CH625210A5 (es) | 1981-09-15 |
| ES451710A1 (es) | 1977-09-01 |
| ATA717076A (de) | 1977-11-15 |
| FI762785A (es) | 1977-04-17 |
| CH624099A5 (es) | 1981-07-15 |
| DE2546319A1 (de) | 1977-04-28 |
| SE433210B (sv) | 1984-05-14 |
| KE3177A (en) | 1982-01-22 |
| SE7611494L (sv) | 1977-04-17 |
| NL180563C (nl) | 1987-03-16 |
| FI62066B (fi) | 1982-07-30 |
| AU1873876A (en) | 1978-04-20 |
| DE2546319C2 (de) | 1986-02-27 |
| DK438976A (da) | 1977-04-17 |
| JPS5251349A (en) | 1977-04-25 |
| HK16582A (en) | 1982-04-16 |
| CH622777A5 (es) | 1981-04-30 |
| AU507034B2 (en) | 1980-01-31 |
| MY8200196A (en) | 1982-12-31 |
| NL7611254A (nl) | 1977-04-19 |
| GB1524637A (en) | 1978-09-13 |
| JPS6016412B2 (ja) | 1985-04-25 |
| FR2327767B1 (es) | 1980-04-25 |
| FI62066C (fi) | 1982-11-10 |
| DK153942B (da) | 1988-09-26 |
| IE44177L (en) | 1977-04-16 |
| NO142524C (no) | 1980-09-03 |
| FR2327767A1 (fr) | 1977-05-13 |
| NO142524B (no) | 1980-05-27 |
| IE44177B1 (en) | 1981-09-09 |
| LU76009A1 (es) | 1977-10-26 |
| NO763532L (es) | 1977-04-19 |
| BE847373A (fr) | 1977-04-15 |
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