ES450391A1 - Un procedimiento para la preparacion de derivados del acido 2-(m-fenoxifenil)-propionico. - Google Patents
Un procedimiento para la preparacion de derivados del acido 2-(m-fenoxifenil)-propionico.Info
- Publication number
- ES450391A1 ES450391A1 ES450391A ES450391A ES450391A1 ES 450391 A1 ES450391 A1 ES 450391A1 ES 450391 A ES450391 A ES 450391A ES 450391 A ES450391 A ES 450391A ES 450391 A1 ES450391 A1 ES 450391A1
- Authority
- ES
- Spain
- Prior art keywords
- phenoxyphenyl
- propionic acid
- acid derivatives
- preparation
- new
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- RDJGLLICXDHJDY-UHFFFAOYSA-N fenoprofen Chemical class OC(=O)C(C)C1=CC=CC(OC=2C=CC=CC=2)=C1 RDJGLLICXDHJDY-UHFFFAOYSA-N 0.000 title 1
- 206010022998 Irritability Diseases 0.000 abstract 1
- 230000001760 anti-analgesic effect Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000002496 gastric effect Effects 0.000 abstract 1
- 208000027866 inflammatory disease Diseases 0.000 abstract 1
- 230000000266 injurious effect Effects 0.000 abstract 1
- 231100000053 low toxicity Toxicity 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
- C07C45/57—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom
- C07C45/58—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom in three-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
- C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/16—Preparation of carboxylic acids or their salts, halides or anhydrides by oxidation
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP12073973A JPS5620294B2 (es) | 1973-10-29 | 1973-10-29 | |
| JP12073873A JPS5620293B2 (es) | 1973-10-29 | 1973-10-29 | |
| JP5389774A JPS5620295B2 (es) | 1974-05-16 | 1974-05-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES450391A1 true ES450391A1 (es) | 1977-11-16 |
Family
ID=27295100
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES431425A Expired ES431425A1 (es) | 1973-10-29 | 1974-10-28 | Un procedimiento para la preparacion de derivados del acido 2-(m-fenoxifenil)-propionico. |
| ES450391A Expired ES450391A1 (es) | 1973-10-29 | 1976-08-02 | Un procedimiento para la preparacion de derivados del acido 2-(m-fenoxifenil)-propionico. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES431425A Expired ES431425A1 (es) | 1973-10-29 | 1974-10-28 | Un procedimiento para la preparacion de derivados del acido 2-(m-fenoxifenil)-propionico. |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US3985779A (es) |
| CA (1) | CA1041531A (es) |
| CH (2) | CH642938A5 (es) |
| DE (1) | DE2451140A1 (es) |
| ES (2) | ES431425A1 (es) |
| FR (1) | FR2248832B1 (es) |
| GB (1) | GB1491498A (es) |
| NL (1) | NL7414134A (es) |
| SE (1) | SE419538B (es) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4145440A (en) * | 1977-08-18 | 1979-03-20 | The Upjohn Company | Liquid suspension of an aluminum salt of ibuprofen |
| DE2950608A1 (de) * | 1978-12-29 | 1980-07-10 | Chinoin Gyogyszer Es Vegyeszet | Verfahren zur herstellung von 2-(3-phenoxy-phenyl)-propionsaeure |
| US4361580A (en) * | 1980-06-20 | 1982-11-30 | The Upjohn Manufacturing Company | Aluminum ibuprofen pharmaceutical suspensions |
| HU181737B (en) * | 1980-07-10 | 1983-11-28 | Chinoin Gyogyszer Es Vegyeszet | Process for preparing diphenyl-ether derivatives |
| IT1175941B (it) * | 1984-02-16 | 1987-08-12 | Stabil Bioterapico Farmachim | Sali d'alluminio mono, bi e trisostituiti degli acidi aril-alcanoici e composizioni farmaceutiche che li contengono |
| ES2163986B1 (es) * | 1999-07-13 | 2003-02-16 | Menarini Lab | Acidos-alfa-arilpropionicos y arilaceticos como inhibidores de la ciclooxigenasa-ii. |
| SE0301010D0 (sv) * | 2003-04-07 | 2003-04-07 | Astrazeneca Ab | Novel compounds |
| SA04250253B1 (ar) | 2003-08-21 | 2009-11-10 | استرازينيكا ايه بي | احماض فينوكسي اسيتيك مستبدلة باعتبارها مركبات صيدلانية لعلاج الامراض التنفسية مثل الربو ومرض الانسداد الرئوي المزمن |
| GB0415320D0 (en) * | 2004-07-08 | 2004-08-11 | Astrazeneca Ab | Novel compounds |
| GB0418830D0 (en) * | 2004-08-24 | 2004-09-22 | Astrazeneca Ab | Novel compounds |
| SI1817282T1 (sl) * | 2004-11-23 | 2011-10-28 | Astrazeneca Ab | Derivati fenoksiocetne kisline, uporabni za zdravljenje respiratornih bolezni |
| BRPI0615948A2 (pt) * | 2005-09-07 | 2011-05-31 | Plexxikon Inc | composto ativo de ppar, sua composição, seu kit e seu uso |
| TW200745003A (en) | 2005-10-06 | 2007-12-16 | Astrazeneca Ab | Novel compounds |
| WO2007039736A1 (en) * | 2005-10-06 | 2007-04-12 | Astrazeneca Ab | Novel compounds |
| JP2009519308A (ja) * | 2005-12-15 | 2009-05-14 | アストラゼネカ・アクチエボラーグ | 呼吸器疾患の処置のための置換ジフェニルエーテル、アミン、スルフィドおよびメタン |
| US20140155358A1 (en) * | 2011-04-11 | 2014-06-05 | Akthelia Pharmaceuticals | Therapeutic Compounds |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB971700A (en) * | 1961-02-02 | 1964-09-30 | Boots Pure Drug Co Ltd | Anti-Inflammatory Agents |
| US3517051A (en) * | 1964-03-20 | 1970-06-23 | Merck & Co Inc | Phenoxy substituted phenylacetic acids |
| US3600437A (en) * | 1969-05-28 | 1971-08-17 | Lilly Co Eli | Substituted phenylalkanoic acids and derivatives thereof |
| US3649679A (en) * | 1968-08-15 | 1972-03-14 | Lilly Co Eli | Substituted phenylalkanoic acid derivatives ii |
| GB1308327A (en) * | 1970-04-14 | 1973-02-21 | Reckitt & Colmann Prod Ltd | Phenylalkane derivatives and processes for the preparation thereof |
-
1974
- 1974-10-28 CA CA212,389A patent/CA1041531A/en not_active Expired
- 1974-10-28 ES ES431425A patent/ES431425A1/es not_active Expired
- 1974-10-28 SE SE7413548A patent/SE419538B/xx not_active IP Right Cessation
- 1974-10-28 DE DE19742451140 patent/DE2451140A1/de not_active Withdrawn
- 1974-10-29 CH CH1058379A patent/CH642938A5/de not_active IP Right Cessation
- 1974-10-29 CH CH1449374A patent/CH613935A5/xx not_active IP Right Cessation
- 1974-10-29 US US05/518,935 patent/US3985779A/en not_active Expired - Lifetime
- 1974-10-29 FR FR7436168A patent/FR2248832B1/fr not_active Expired
- 1974-10-29 NL NL7414134A patent/NL7414134A/xx unknown
- 1974-10-29 GB GB46851/74A patent/GB1491498A/en not_active Expired
-
1976
- 1976-08-02 ES ES450391A patent/ES450391A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| CH613935A5 (es) | 1979-10-31 |
| SE7413548L (es) | 1975-04-30 |
| ES431425A1 (es) | 1977-01-16 |
| FR2248832A1 (es) | 1975-05-23 |
| US3985779A (en) | 1976-10-12 |
| NL7414134A (nl) | 1975-05-02 |
| FR2248832B1 (es) | 1978-07-21 |
| SE419538B (sv) | 1981-08-10 |
| DE2451140A1 (de) | 1975-04-30 |
| CA1041531A (en) | 1978-10-31 |
| CH642938A5 (de) | 1984-05-15 |
| GB1491498A (en) | 1977-11-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19981001 |