ES436458A1 - Procedimiento para la preparacion de derivados alcohilicos en c22 de la digoxina. - Google Patents
Procedimiento para la preparacion de derivados alcohilicos en c22 de la digoxina.Info
- Publication number
- ES436458A1 ES436458A1 ES436458A ES436458A ES436458A1 ES 436458 A1 ES436458 A1 ES 436458A1 ES 436458 A ES436458 A ES 436458A ES 436458 A ES436458 A ES 436458A ES 436458 A1 ES436458 A1 ES 436458A1
- Authority
- ES
- Spain
- Prior art keywords
- digoxin
- preparation
- alcohol
- derivatives
- digoxin derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- LTMHDMANZUZIPE-PUGKRICDSA-N digoxin Chemical class C1[C@H](O)[C@H](O)[C@@H](C)O[C@H]1O[C@@H]1[C@@H](C)O[C@@H](O[C@@H]2[C@H](O[C@@H](O[C@@H]3C[C@@H]4[C@]([C@@H]5[C@H]([C@]6(CC[C@@H]([C@@]6(C)[C@H](O)C5)C=5COC(=O)C=5)O)CC4)(C)CC3)C[C@@H]2O)C)C[C@@H]1O LTMHDMANZUZIPE-PUGKRICDSA-N 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- FDWRIIDFYSUTDP-KVTDHHQDSA-N (2r,4r,5s,6r)-6-methyloxane-2,4,5-triol Chemical group C[C@H]1O[C@@H](O)C[C@@H](O)[C@@H]1O FDWRIIDFYSUTDP-KVTDHHQDSA-N 0.000 abstract 1
- FDWRIIDFYSUTDP-UHFFFAOYSA-N 102850-49-7 Natural products CC1OC(O)CC(O)C1O FDWRIIDFYSUTDP-UHFFFAOYSA-N 0.000 abstract 1
- JWFRNGYBHLBCMB-UHFFFAOYSA-N D-Canaytose Natural products CC(O)C(O)C(O)CC=O JWFRNGYBHLBCMB-UHFFFAOYSA-N 0.000 abstract 1
- LTMHDMANZUZIPE-AMTYYWEZSA-N Digoxin Natural products O([C@H]1[C@H](C)O[C@H](O[C@@H]2C[C@@H]3[C@@](C)([C@@H]4[C@H]([C@]5(O)[C@](C)([C@H](O)C4)[C@H](C4=CC(=O)OC4)CC5)CC3)CC2)C[C@@H]1O)[C@H]1O[C@H](C)[C@@H](O[C@H]2O[C@@H](C)[C@H](O)[C@@H](O)C2)[C@@H](O)C1 LTMHDMANZUZIPE-AMTYYWEZSA-N 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- KEAYESYHFKHZAL-UHFFFAOYSA-N Sodium Chemical compound [Na] KEAYESYHFKHZAL-UHFFFAOYSA-N 0.000 abstract 1
- 125000003158 alcohol group Chemical group 0.000 abstract 1
- 230000001476 alcoholic effect Effects 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 229960005156 digoxin Drugs 0.000 abstract 1
- LTMHDMANZUZIPE-UHFFFAOYSA-N digoxine Natural products C1C(O)C(O)C(C)OC1OC1C(C)OC(OC2C(OC(OC3CC4C(C5C(C6(CCC(C6(C)C(O)C5)C=5COC(=O)C=5)O)CC4)(C)CC3)CC2O)C)CC1O LTMHDMANZUZIPE-UHFFFAOYSA-N 0.000 abstract 1
- XMBWDFGMSWQBCA-UHFFFAOYSA-N hydrogen iodide Chemical compound I XMBWDFGMSWQBCA-UHFFFAOYSA-N 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 239000003880 polar aprotic solvent Substances 0.000 abstract 1
- 229910000104 sodium hydride Inorganic materials 0.000 abstract 1
- 239000012312 sodium hydride Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J19/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 by a lactone ring
- C07J19/005—Glycosides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2418127A DE2418127A1 (de) | 1974-04-13 | 1974-04-13 | C22-alkyl-derivate des alpha- und beta-methyldigoxins und verfahren zur herstellung derselben |
| DE19742433563 DE2433563C2 (de) | 1974-07-12 | 1974-07-12 | Verfahren zur Herstellung von C22- Alkyl-Derivaten des Digoxins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES436458A1 true ES436458A1 (es) | 1977-01-01 |
Family
ID=25766973
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES436458A Expired ES436458A1 (es) | 1974-04-13 | 1975-04-09 | Procedimiento para la preparacion de derivados alcohilicos en c22 de la digoxina. |
Country Status (9)
| Country | Link |
|---|---|
| JP (1) | JPS5851960B2 (es) |
| AR (1) | AR202973A1 (es) |
| CA (1) | CA1033714A (es) |
| ES (1) | ES436458A1 (es) |
| FI (1) | FI54317C (es) |
| FR (1) | FR2267328B1 (es) |
| GB (1) | GB1449804A (es) |
| NL (1) | NL7504091A (es) |
| SE (1) | SE396392B (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61171714U (es) * | 1985-04-12 | 1986-10-24 |
-
1975
- 1975-01-01 AR AR20297375D patent/AR202973A1/es active
- 1975-04-02 CA CA223,698A patent/CA1033714A/en not_active Expired
- 1975-04-07 NL NL7504091A patent/NL7504091A/xx not_active Application Discontinuation
- 1975-04-08 FI FI751053A patent/FI54317C/fi not_active IP Right Cessation
- 1975-04-08 SE SE7504005A patent/SE396392B/xx unknown
- 1975-04-09 GB GB1459675A patent/GB1449804A/en not_active Expired
- 1975-04-09 ES ES436458A patent/ES436458A1/es not_active Expired
- 1975-04-11 FR FR7511370A patent/FR2267328B1/fr not_active Expired
- 1975-04-14 JP JP50045117A patent/JPS5851960B2/ja not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| AU8004375A (en) | 1976-10-14 |
| JPS50137970A (es) | 1975-11-01 |
| NL7504091A (nl) | 1975-10-15 |
| FI54317C (fi) | 1978-11-10 |
| FI54317B (fi) | 1978-07-31 |
| FR2267328B1 (es) | 1978-06-30 |
| FI751053A (es) | 1975-10-14 |
| GB1449804A (en) | 1976-09-15 |
| SE7504005L (sv) | 1975-10-14 |
| CA1033714A (en) | 1978-06-27 |
| JPS5851960B2 (ja) | 1983-11-19 |
| AR202973A1 (es) | 1975-07-31 |
| FR2267328A1 (es) | 1975-11-07 |
| SE396392B (sv) | 1977-09-19 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES420628A1 (es) | Procedimiento para la preparacion de n-(furiu-metil)-morfi-nanos. | |
| ES483410A1 (es) | Un procedimiento para la preparacion de un derivado de clo- rambucil | |
| ES408274A1 (es) | Procedimiento para la preparacion de 2-(furilmetil)-6,7- benzomorfanos. | |
| ES436458A1 (es) | Procedimiento para la preparacion de derivados alcohilicos en c22 de la digoxina. | |
| ES8302026A1 (es) | Procedimiento para la preparacion de 11-metilen- 15-esteroi-des | |
| ES429020A1 (es) | Procedimiento para preparar nuevos derivados de tiazol-5- metanol. | |
| ES410934A1 (es) | Procedimiento para la preparacion de acidos indolcarboxili-cos. | |
| ES435204A1 (es) | Procedimiento para la preparacion de 11beta -fluor-andros- tenos. | |
| ES427869A1 (es) | Procedimiento para la preparacion de esteres alcoholicos deacido 5-fenilsulfinil-2-bencimidazol-carbamico. | |
| ES458389A1 (es) | Procedimiento para preparar derivados de prostaglandina. | |
| ES402328A1 (es) | Procedimiento para preparar 4-hidroxibenzodio-xol. | |
| ES430059A1 (es) | Procedimiento para la obtencion de un nuevo derivado del a-cido nicotinico. | |
| ES426350A1 (es) | Procedimiento para la preparacion de derivados del acido p-isobutil-fenilacetico. | |
| ES437041A1 (es) | Un procedimiento para preparar derivados de 1-ftalazona. | |
| ES385084A1 (es) | Un procedimiento para la preparacion de nuevos derivados deacido glucuronico. | |
| ES380392A1 (es) | Procedimiento para la preparacion de un compuesto de 5-ni- tro-furil-pirazol. | |
| ES377444A1 (es) | Procedimiento de preparacion de nuevos eteres de la 2-hi- droxibenzamida. | |
| ES386181A2 (es) | Procedimiento para la preparacion de eteres diglicidilicos. | |
| ES445254A1 (es) | Un procedimiento para la preparacion de acidos metil-2 o 3- cefem-4-carboxilicos 3-sustituidos. | |
| ES431523A1 (es) | Un procedimiento para preparar un derivado de ftalazona. | |
| ES384815A1 (es) | Un procedimiento para la preparacion de nicotinatos y n-o- xido-nicotinatos de aminas alifaticas. | |
| ES447846A1 (es) | Un procedimiento para la obtencion de acidos cromona-2-car- boxilicos. | |
| ES459574A3 (es) | Procedimiento de preparacion de nuevos derivados del indol. | |
| ES369000A2 (es) | Un metodo de preparar policarboxilatos. | |
| ES433453A1 (es) | Procedimiento para la preparacion de derivados de arilpipe-razinicos de la adenina. |