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ES433493A1 - Procedure for the preparation of ester cis 3,3,5-tri-methylcychlonic of the dl-alpha-nicotinoiloxyphenylaceal acid. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the preparation of ester cis 3,3,5-tri-methylcychlonic of the dl-alpha-nicotinoiloxyphenylaceal acid. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES433493A1
ES433493A1 ES433493A ES433493A ES433493A1 ES 433493 A1 ES433493 A1 ES 433493A1 ES 433493 A ES433493 A ES 433493A ES 433493 A ES433493 A ES 433493A ES 433493 A1 ES433493 A1 ES 433493A1
Authority
ES
Spain
Prior art keywords
acid
alpha
translation
preparation
machine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES433493A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GAVER SA
Original Assignee
GAVER SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GAVER SA filed Critical GAVER SA
Publication of ES433493A1 publication Critical patent/ES433493A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Process for the preparation of the cis-3,3,5-trimethylcyclohexyl ester of dl-alpha-nicotinoyloxyphenylacetic acid, of the formula ** (see formula) ** Characterized in that the 3,3,5-trimethylcyclohexyl ester of mandelic acid and nicotinoyl chloride hydrochloride are reacted in stoichiometric proportion or with a slight excess of the latter product, in organic solvent solution and at elevated temperature, because the product is separated formed from the reaction mixture by precipitation with p.toluenesulfonic acid and then released from its p.toluensulfonate with an alkaline base. (Machine-translation by Google Translate, not legally binding)
ES433493A 1974-01-03 1975-01-02 Procedure for the preparation of ester cis 3,3,5-tri-methylcychlonic of the dl-alpha-nicotinoiloxyphenylaceal acid. (Machine-translation by Google Translate, not legally binding) Expired ES433493A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH2274 1974-01-03

Publications (1)

Publication Number Publication Date
ES433493A1 true ES433493A1 (en) 1976-12-01

Family

ID=4177599

Family Applications (1)

Application Number Title Priority Date Filing Date
ES433493A Expired ES433493A1 (en) 1974-01-03 1975-01-02 Procedure for the preparation of ester cis 3,3,5-tri-methylcychlonic of the dl-alpha-nicotinoiloxyphenylaceal acid. (Machine-translation by Google Translate, not legally binding)

Country Status (10)

Country Link
JP (1) JPS50105670A (en)
BE (1) BE824034A (en)
DE (1) DE2461909A1 (en)
DK (1) DK678174A (en)
ES (1) ES433493A1 (en)
FI (1) FI378374A (en)
FR (1) FR2256757A1 (en)
NL (1) NL7500065A (en)
NO (1) NO750005L (en)
SE (1) SE7416232L (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1175810B (en) * 1984-03-07 1987-07-15 Ravizza Spa PROCESS FOR THE PREPARATION OF CIS-3,3,5-TRIMETYLCYCLOHESYL-D, L- (3-PYRIDIN-CARBOSE) -PHENYLACETATE

Also Published As

Publication number Publication date
FR2256757A1 (en) 1975-08-01
SE7416232L (en) 1975-07-04
NO750005L (en) 1975-07-28
DE2461909A1 (en) 1975-07-17
NL7500065A (en) 1975-07-07
JPS50105670A (en) 1975-08-20
FI378374A (en) 1975-07-04
DK678174A (en) 1975-09-01
BE824034A (en) 1975-04-16

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