ES432918A1 - Phenethylaralkylamine compounds and their preparation - Google Patents
Phenethylaralkylamine compounds and their preparationInfo
- Publication number
- ES432918A1 ES432918A1 ES432918A ES432918A ES432918A1 ES 432918 A1 ES432918 A1 ES 432918A1 ES 432918 A ES432918 A ES 432918A ES 432918 A ES432918 A ES 432918A ES 432918 A1 ES432918 A1 ES 432918A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- represent hydrogen
- alkyl
- alkenyl
- different
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Cell Electrode Carriers And Collectors (AREA)
Abstract
A method of preparing phenylalkyl karamines of the formula: **(See formula)** where R4 and R5 are lower alkyl substituents of 1 to 3 carbon atoms; R2 and R3 are the same or different and represent hydrogen, alkyl, branched chain alkyl, alkenyl, alkynyl and can be linked together or alternatively can be linked through a carbon, nitrogen, oxygen or sulfur atom to form a heterocyclic ring with 5 or 6 atoms; and X and X'are the same or different and represent hydrogen, halogen, lower alkyl, lower alkenyl, perfluoroalkyl, phenyl, substituted phenyl, acyl, perfluoracil, amino, alkylamino, dialkylamino, acyl amino, perfluororacylamino, alkylsulfonylamino, hydroxy, alkoxy, perfluoroalkoxy, cyano, carboxy, carbamoflo, alkylcarbamoyl, dialkylcarbamoyl, carboalkoxy, mercapto, alkylmercapto, perfluoroalkylmercapto, alkylsulfonyl, perfluoroalkylsulfonyl, sulfainoyl, alkylsulfamoyl or dialkylsulfamoyl; whose process comprises the reduction by catalytic hydrogenation of a compound of the formula: **(See formula)** where R2, R3, R4, R5, X and X'have the meaning given above. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10688971A | 1971-01-15 | 1971-01-15 | |
| US20570871A | 1971-12-07 | 1971-12-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES432918A1 true ES432918A1 (en) | 1976-11-01 |
Family
ID=26804135
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES398855A Expired ES398855A1 (en) | 1971-01-15 | 1972-01-13 | Phenethylaralkylamine compounds and their preparation |
| ES432918A Expired ES432918A1 (en) | 1971-01-15 | 1974-12-13 | Phenethylaralkylamine compounds and their preparation |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES398855A Expired ES398855A1 (en) | 1971-01-15 | 1972-01-13 | Phenethylaralkylamine compounds and their preparation |
Country Status (18)
| Country | Link |
|---|---|
| JP (1) | JPS5425015B1 (en) |
| AR (1) | AR192907A1 (en) |
| AU (1) | AU469273B2 (en) |
| BE (1) | BE778049A (en) |
| CA (1) | CA1008884A (en) |
| CH (2) | CH572889A5 (en) |
| DE (1) | DE2201804C3 (en) |
| ES (2) | ES398855A1 (en) |
| FI (1) | FI54701C (en) |
| FR (1) | FR2121849B1 (en) |
| GB (1) | GB1355449A (en) |
| HU (1) | HU165402B (en) |
| IE (1) | IE35972B1 (en) |
| IL (1) | IL38528A (en) |
| NL (1) | NL7200202A (en) |
| NO (1) | NO135027C (en) |
| PH (2) | PH11341A (en) |
| SE (2) | SE388603B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA874448B (en) * | 1986-06-20 | 1989-02-22 | Mcneilab Inc | Cis & trans stilbenes and their composition for the treatment of hypertension |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH386443A (en) * | 1959-12-16 | 1965-01-15 | Geigy Ag J R | Process for the preparation of new tetrasubstituted alkylenediamines |
| US3719712A (en) * | 1969-09-29 | 1973-03-06 | Merck & Co Inc | 2-phenylethynyl-benzyl-amines |
-
1972
- 1972-01-03 NO NO724A patent/NO135027C/no unknown
- 1972-01-03 SE SE7200013A patent/SE388603B/en unknown
- 1972-01-04 FI FI11/72A patent/FI54701C/en active
- 1972-01-06 NL NL7200202A patent/NL7200202A/xx not_active Application Discontinuation
- 1972-01-10 IL IL38528A patent/IL38528A/en unknown
- 1972-01-11 PH PH13180A patent/PH11341A/en unknown
- 1972-01-11 CA CA132,195A patent/CA1008884A/en not_active Expired
- 1972-01-11 AU AU37796/72A patent/AU469273B2/en not_active Expired
- 1972-01-11 IE IE42/72A patent/IE35972B1/en unknown
- 1972-01-12 HU HUME1457A patent/HU165402B/hu unknown
- 1972-01-12 GB GB149472A patent/GB1355449A/en not_active Expired
- 1972-01-13 CH CH54872A patent/CH572889A5/xx not_active IP Right Cessation
- 1972-01-13 CH CH1417275A patent/CH573392A5/xx not_active IP Right Cessation
- 1972-01-13 ES ES398855A patent/ES398855A1/en not_active Expired
- 1972-01-13 AR AR240071A patent/AR192907A1/en active
- 1972-01-14 FR FR7201242A patent/FR2121849B1/fr not_active Expired
- 1972-01-14 DE DE2201804A patent/DE2201804C3/en not_active Expired
- 1972-01-14 BE BE778049A patent/BE778049A/en unknown
- 1972-01-17 JP JP627572A patent/JPS5425015B1/ja active Pending
-
1974
- 1974-11-12 PH PH16506A patent/PH11987A/en unknown
- 1974-12-13 ES ES432918A patent/ES432918A1/en not_active Expired
-
1975
- 1975-02-10 SE SE7501439A patent/SE398344B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GB1355449A (en) | 1974-06-05 |
| IL38528A0 (en) | 1972-03-28 |
| DE2201804A1 (en) | 1972-07-27 |
| IE35972B1 (en) | 1976-07-07 |
| IL38528A (en) | 1975-05-22 |
| PH11341A (en) | 1977-11-02 |
| CA1008884A (en) | 1977-04-19 |
| SE388603B (en) | 1976-10-11 |
| FI54701B (en) | 1978-10-31 |
| ES398855A1 (en) | 1975-06-16 |
| NO135027C (en) | 1977-01-26 |
| HU165402B (en) | 1974-08-28 |
| JPS5425015B1 (en) | 1979-08-24 |
| FR2121849B1 (en) | 1975-12-26 |
| DE2201804B2 (en) | 1974-07-18 |
| AU3779672A (en) | 1973-07-12 |
| SE7501439L (en) | 1975-02-10 |
| AU469273B2 (en) | 1976-02-12 |
| BE778049A (en) | 1972-07-14 |
| FI54701C (en) | 1979-02-12 |
| FR2121849A1 (en) | 1972-08-25 |
| PH11987A (en) | 1978-10-05 |
| CH573392A5 (en) | 1976-03-15 |
| CH572889A5 (en) | 1976-02-27 |
| AR192907A1 (en) | 1973-03-21 |
| SE398344B (en) | 1977-12-19 |
| NL7200202A (en) | 1972-07-18 |
| NO135027B (en) | 1976-10-18 |
| DE2201804C3 (en) | 1975-03-20 |
| IE35972L (en) | 1972-07-15 |
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