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ES423129A1 - Procedure for the obtaining of new anti-inflammatory drugs. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the obtaining of new anti-inflammatory drugs. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES423129A1
ES423129A1 ES423129A ES423129A ES423129A1 ES 423129 A1 ES423129 A1 ES 423129A1 ES 423129 A ES423129 A ES 423129A ES 423129 A ES423129 A ES 423129A ES 423129 A1 ES423129 A1 ES 423129A1
Authority
ES
Spain
Prior art keywords
phenyl
translation
procedure
machine
legally binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES423129A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
HOSBON INVEST
Original Assignee
HOSBON INVEST
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by HOSBON INVEST filed Critical HOSBON INVEST
Priority to ES423129A priority Critical patent/ES423129A1/en
Priority to DE2456312A priority patent/DE2456312C3/en
Priority to FR7501495A priority patent/FR2260342A1/en
Priority to BE152932A priority patent/BE825044A/en
Publication of ES423129A1 publication Critical patent/ES423129A1/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/28Two oxygen or sulfur atoms
    • C07D231/30Two oxygen or sulfur atoms attached in positions 3 and 5
    • C07D231/32Oxygen atoms
    • C07D231/34Oxygen atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Procedure for obtaining new anti-inflammatory drugs, namely the addition products or salts between 4-butyl-2-phenyl-1- (p-hydroxy-phenyl) -3,5-pyrazolidinedione and diethylenediamine, which respond to the formula: ** (see formula) ** Wherein n can be 1 or 2, characterized in that 4-butyl-2-phenyl-1- (p-hydroxy-phenyl) -3,5-pyrazolidinedione is reacted in a homogeneous organic or aqueous organic medium with diethylene diamine, in molar stoichiometric ratio 1: 1 or 2: 1, depending on the compound to be obtained, or with slight excess of some of the reagents, finally isolating the products formed, normally by filtration or centrifugation. (Machine-translation by Google Translate, not legally binding)
ES423129A 1974-02-12 1974-02-12 Procedure for the obtaining of new anti-inflammatory drugs. (Machine-translation by Google Translate, not legally binding) Expired ES423129A1 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
ES423129A ES423129A1 (en) 1974-02-12 1974-02-12 Procedure for the obtaining of new anti-inflammatory drugs. (Machine-translation by Google Translate, not legally binding)
DE2456312A DE2456312C3 (en) 1974-02-12 1974-11-28 The salt of 4-butyl-2-phenyl-l- (p-hydroxyphenyl) -pyrazolidinedione-
FR7501495A FR2260342A1 (en) 1974-02-12 1975-01-17 Piperazine phenoxybutazone salts - as antiinflammatory agents having good gastric tolerance and low toxicity
BE152932A BE825044A (en) 1974-02-12 1975-01-31 NEW OXYPHENBUTAZONE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATIONS

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES423129A ES423129A1 (en) 1974-02-12 1974-02-12 Procedure for the obtaining of new anti-inflammatory drugs. (Machine-translation by Google Translate, not legally binding)

Publications (1)

Publication Number Publication Date
ES423129A1 true ES423129A1 (en) 1976-04-16

Family

ID=8465944

Family Applications (1)

Application Number Title Priority Date Filing Date
ES423129A Expired ES423129A1 (en) 1974-02-12 1974-02-12 Procedure for the obtaining of new anti-inflammatory drugs. (Machine-translation by Google Translate, not legally binding)

Country Status (4)

Country Link
BE (1) BE825044A (en)
DE (1) DE2456312C3 (en)
ES (1) ES423129A1 (en)
FR (1) FR2260342A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU203538B (en) * 1988-03-10 1991-08-28 Richter Gedeon Vegyeszet Process for producing 1,2-diphenyl-3,5-dioxy-4-butyl-pirazolidin-sodium-monohydrate

Also Published As

Publication number Publication date
BE825044A (en) 1975-05-15
FR2260342A1 (en) 1975-09-05
DE2456312B2 (en) 1978-06-08
DE2456312C3 (en) 1979-02-01
DE2456312A1 (en) 1975-08-21
FR2260342B1 (en) 1979-08-10

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