ES421068A1 - Procedure for the preparation of new 2-phenylamine-substitute imidazolines. (Machine-translation by Google Translate, not legally binding) - Google Patents
Procedure for the preparation of new 2-phenylamine-substitute imidazolines. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES421068A1 ES421068A1 ES421068A ES421068A ES421068A1 ES 421068 A1 ES421068 A1 ES 421068A1 ES 421068 A ES421068 A ES 421068A ES 421068 A ES421068 A ES 421068A ES 421068 A1 ES421068 A1 ES 421068A1
- Authority
- ES
- Spain
- Prior art keywords
- translation
- procedure
- preparation
- machine
- legally binding
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/44—Nitrogen atoms not forming part of a nitro radical
- C07D233/50—Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Procedure for the preparation of new substituted 2-phenylaminoimidazolines of the general formula **(See formula)** wherein R1, R2 and R3, which may be the same or different, signify a hydrogen or fluorine, chlorine or bromine atom, or a methyl, ethyl, methoxy, hydroxy, trifluoromethyl or cyano group and R5 signifies a straight or branched with up to 12 carbon atoms, as well as their acid addition salts, characterized in that a metal salt of 2-phenylamino-imidazoline- (2) of the general formula is reacted **(See formula)** Where R1 through R3 are as defined above, Me + means a metal cation, preferably an alkali metal cation, with a halide of the general formula V Hal - R5 and eventually the product is transformed into an acid addition salt. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19722259160 DE2259160A1 (en) | 1972-12-02 | 1972-12-02 | NEW SUBSTITUTED 2-PHENYLAMINOIMIDAZOLINE, THEIR ACID-ADDITIONAL SALTS AND METHOD FOR MANUFACTURING THE SAME AND THEIR USE AS A MEDICINAL PRODUCT |
Publications (1)
Publication Number | Publication Date |
---|---|
ES421068A1 true ES421068A1 (en) | 1976-04-16 |
Family
ID=5863396
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES421068A Expired ES421068A1 (en) | 1972-12-02 | 1973-12-01 | Procedure for the preparation of new 2-phenylamine-substitute imidazolines. (Machine-translation by Google Translate, not legally binding) |
ES421067A Expired ES421067A1 (en) | 1972-12-02 | 1973-12-01 | Procedure for the preparation of new 2-phenylamine-substitute imidazolines. (Machine-translation by Google Translate, not legally binding) |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES421067A Expired ES421067A1 (en) | 1972-12-02 | 1973-12-01 | Procedure for the preparation of new 2-phenylamine-substitute imidazolines. (Machine-translation by Google Translate, not legally binding) |
Country Status (8)
Country | Link |
---|---|
JP (1) | JPS4986365A (en) |
AT (1) | AT326118B (en) |
AU (1) | AU6309173A (en) |
BE (1) | BE808150A (en) |
DE (1) | DE2259160A1 (en) |
ES (2) | ES421068A1 (en) |
FR (1) | FR2208671A1 (en) |
NL (1) | NL7316405A (en) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2636732A1 (en) * | 1976-08-14 | 1978-02-16 | Boehringer Sohn Ingelheim | NEW SUBSTITUTED 2-PHENYLAMINO IMIDAZOLINE (2), THE ACID ADDITION SALTS THEREOF, THE MEDICINAL PRODUCTS CONTAINING THE SAME AND METHOD FOR THE PRODUCTION THEREOF |
DE2830278A1 (en) * | 1978-07-10 | 1980-01-31 | Boehringer Sohn Ingelheim | NEW SUBSTITUTED 2-PHENYLAMINO-IMIDAZOLINE (2), THE ACID ADDITION SALTS THEREOF, THE MEDICINAL PRODUCTS CONTAINING THE SAME AND METHOD FOR THE PRODUCTION THEREOF |
DE2947563A1 (en) * | 1979-11-26 | 1981-06-04 | C.H. Boehringer Sohn, 6507 Ingelheim | NEW SUBSTITUTED 2-PHENYLAMINO-IMIDAZOLINE (2), THE ACID ADDITION SALTS THEREOF, THE MEDICINAL PRODUCTS CONTAINING THE SAME AND METHOD FOR THE PRODUCTION THEREOF |
DE2949287A1 (en) * | 1979-12-07 | 1981-06-11 | C.H. Boehringer Sohn, 6507 Ingelheim | NEW SUBSTITUTED 2-PHENYLAMINO-IMIDAZOLINE (2), THE ACID ADDITION SALTS THEREOF, THE MEDICINAL PRODUCTS CONTAINING THE SAME AND METHOD FOR THE PRODUCTION THEREOF |
DE3200258A1 (en) * | 1982-01-07 | 1983-07-21 | Lentia GmbH Chem. u. pharm. Erzeugnisse - Industriebedarf, 8000 München | SUBSTITUTED 1-BENZOYL-2-PHENYLIMINO IMIDAZOLIDINE, THE ACID ADDITION SALTS THEREOF, METHOD FOR THE PRODUCTION THEREOF AND THE MEDICINAL PRODUCTS CONTAINING THE SAME |
IT1303672B1 (en) * | 1998-07-28 | 2001-02-23 | Nicox Sa | NITRATED SALTS OF DRUGS ACTIVE IN BONE DISORDERS |
EP1333028A1 (en) * | 2002-01-31 | 2003-08-06 | Boehringer Ingelheim Pharma GmbH & Co.KG | 2'-Halo-3',5'-dialkoxyphen-1'-yl-imino-2-imidazolidine derivatives and the use thereof for the treatment of urinary incontinence |
US6703409B2 (en) | 2002-01-31 | 2004-03-09 | Boehringer Ingelheim Pharma Gmbh & Co Kg | 2′-Halo-3′,5′-dialkoxyphen-1′-yl-imino-2-imidazolidine and the use thereof as a drug |
PT2303264T (en) * | 2008-06-09 | 2018-05-14 | Allergan Inc | Methods of treating alpha adrenergic mediated conditions using imidazoline derivatives |
-
1972
- 1972-12-02 DE DE19722259160 patent/DE2259160A1/en active Pending
-
1973
- 1973-11-09 AT AT943273A patent/AT326118B/en not_active IP Right Cessation
- 1973-11-30 NL NL7316405A patent/NL7316405A/xx unknown
- 1973-11-30 AU AU63091/73A patent/AU6309173A/en not_active Expired
- 1973-12-01 ES ES421068A patent/ES421068A1/en not_active Expired
- 1973-12-01 JP JP13483173A patent/JPS4986365A/ja active Pending
- 1973-12-01 ES ES421067A patent/ES421067A1/en not_active Expired
- 1973-12-03 FR FR7343033A patent/FR2208671A1/en not_active Withdrawn
- 1973-12-03 BE BE138456A patent/BE808150A/en unknown
Also Published As
Publication number | Publication date |
---|---|
ES421067A1 (en) | 1976-04-01 |
BE808150A (en) | 1974-06-04 |
DE2259160A1 (en) | 1974-06-06 |
ATA943273A (en) | 1975-02-15 |
FR2208671A1 (en) | 1974-06-28 |
JPS4986365A (en) | 1974-08-19 |
AU6309173A (en) | 1975-06-05 |
NL7316405A (en) | 1974-06-05 |
AT326118B (en) | 1975-11-25 |
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