ES412107A1 - Procedimiento para la obtencion de nuevos derivados de dia-zepina. - Google Patents
Procedimiento para la obtencion de nuevos derivados de dia-zepina.Info
- Publication number
- ES412107A1 ES412107A1 ES412107A ES412107A ES412107A1 ES 412107 A1 ES412107 A1 ES 412107A1 ES 412107 A ES412107 A ES 412107A ES 412107 A ES412107 A ES 412107A ES 412107 A1 ES412107 A1 ES 412107A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- group
- carbon atoms
- indicated
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000002576 diazepinyl group Chemical class N1N=C(C=CC=C1)* 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 8
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 4
- 125000003545 alkoxy group Chemical group 0.000 abstract 3
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 3
- 229910052740 iodine Inorganic materials 0.000 abstract 2
- 150000007522 mineralic acids Chemical class 0.000 abstract 2
- 150000007524 organic acids Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 abstract 1
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 239000007795 chemical reaction product Substances 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 125000004663 dialkyl amino group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 239000011630 iodine Substances 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 125000004573 morpholin-4-yl group Chemical group N1(CCOCC1)* 0.000 abstract 1
- 235000005985 organic acids Nutrition 0.000 abstract 1
- -1 polymethylenimino residue Polymers 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
- A61K31/5517—1,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK560071AA DK138854B (da) | 1970-11-23 | 1971-11-15 | Analogifremgangsmåde til fremstilling af s-triazolo(4,3-a)(1,4)benzodiazepinderivater eller 5-oxider eller salte deraf. |
| CH291772A CH567509A5 (en) | 1972-02-29 | 1972-02-29 | Diazepin derivs - prepd from triazolobenzodiazepinones and phenylmagnesiumhalide are central depressants, tranquillisers and |
| DK248872AA DK140988B (da) | 1971-11-15 | 1972-05-18 | Analogifremgangsmåde til fremstilling af et s-triazolo (4,3-a)(1,4) benzodiazepinderivater. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES412107A1 true ES412107A1 (es) | 1976-06-16 |
Family
ID=27174020
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES412107A Expired ES412107A1 (es) | 1971-11-15 | 1973-02-27 | Procedimiento para la obtencion de nuevos derivados de dia-zepina. |
Country Status (6)
| Country | Link |
|---|---|
| JP (1) | JPS5619353B2 (es) |
| DK (1) | DK140988B (es) |
| ES (1) | ES412107A1 (es) |
| FI (1) | FI53821C (es) |
| PL (1) | PL89263B1 (es) |
| SE (1) | SE415101B (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1234810A (en) * | 1983-12-19 | 1988-04-05 | Steve Nichols | Non-hygroscopic adinazolam methanesulfonate salt and process therefor |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3987052A (en) * | 1969-03-17 | 1976-10-19 | The Upjohn Company | 6-Phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepines |
-
1972
- 1972-05-15 FI FI1368/72A patent/FI53821C/fi active
- 1972-05-17 SE SE7206441A patent/SE415101B/xx unknown
- 1972-05-18 DK DK248872AA patent/DK140988B/da unknown
-
1973
- 1973-02-27 ES ES412107A patent/ES412107A1/es not_active Expired
- 1973-02-27 PL PL1973160943A patent/PL89263B1/pl unknown
- 1973-02-28 JP JP2331573A patent/JPS5619353B2/ja not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FI53821C (fi) | 1978-08-10 |
| PL89263B1 (es) | 1976-11-30 |
| JPS4892399A (es) | 1973-11-30 |
| DK140988C (es) | 1980-06-02 |
| DK140988B (da) | 1979-12-17 |
| JPS5619353B2 (es) | 1981-05-07 |
| SE415101B (sv) | 1980-09-08 |
| FI53821B (fi) | 1978-05-02 |
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