ES411341A1 - Procedimiento para la preparacion de compuestos heteroci- clicos sustituidos por un radical guanidinilideno. - Google Patents

Procedimiento para la preparacion de compuestos heteroci- clicos sustituidos por un radical guanidinilideno.

Info

Publication number: ES411341A1
Authority: ES; Spain
Prior art keywords: radical; carbon atoms; lower alcohol; radicals; straight
Prior art date: 1972-02-08
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

ES411341A

Other languages

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Boehringer Ingelheim Pharma GmbH and Co KG

Original Assignee

Dr Karl Thomae GmbH

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1972-02-08

Filing date

1973-02-06

Publication date

1976-03-16

1973-02-06 Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH

1976-03-16 Publication of ES411341A1 publication Critical patent/ES411341A1/es

Status Expired legal-status Critical Current

Links

ZRALSGWEFCBTJO-UHFFFAOYSA-N Guanidine Chemical compound NC(N)=N ZRALSGWEFCBTJO-UHFFFAOYSA-N 0.000 title 2
CHJJGSNFBQVOTG-UHFFFAOYSA-N N-methyl-guanidine Natural products CNC(N)=N CHJJGSNFBQVOTG-UHFFFAOYSA-N 0.000 title 1
SWSQBOPZIKWTGO-UHFFFAOYSA-N dimethylaminoamidine Natural products CN(C)C(N)=N SWSQBOPZIKWTGO-UHFFFAOYSA-N 0.000 title 1
-1 guanidinylidene radical Chemical class 0.000 abstract 14
125000004432 carbon atom Chemical group C* 0.000 abstract 10
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 6
150000003839 salts Chemical class 0.000 abstract 4
CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical compound [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 3
150000003254 radicals Chemical class 0.000 abstract 3
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
239000002253 acid Substances 0.000 abstract 2
150000001412 amines Chemical class 0.000 abstract 2
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 2
125000005843 halogen group Chemical group 0.000 abstract 2
150000007522 mineralic acids Chemical class 0.000 abstract 2
229910052757 nitrogen Inorganic materials 0.000 abstract 2
125000004433 nitrogen atom Chemical group N* 0.000 abstract 2
150000007524 organic acids Chemical class 0.000 abstract 2
KRTGJZMJJVEKRX-UHFFFAOYSA-N 2-phenylethan-1-yl Chemical compound [CH2]CC1=CC=CC=C1 KRTGJZMJJVEKRX-UHFFFAOYSA-N 0.000 abstract 1
125000003341 7 membered heterocyclic group Chemical group 0.000 abstract 1
ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 abstract 1
PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 1
125000004397 aminosulfonyl group Chemical group NS(=O)(=O)* 0.000 abstract 1
125000001246 bromo group Chemical group Br* 0.000 abstract 1
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
229910052801 chlorine Inorganic materials 0.000 abstract 1
239000000460 chlorine Substances 0.000 abstract 1
125000001309 chloro group Chemical group Cl* 0.000 abstract 1
229910052731 fluorine Inorganic materials 0.000 abstract 1
239000011737 fluorine Substances 0.000 abstract 1
150000002391 heterocyclic compounds Chemical group 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
125000002560 nitrile group Chemical group 0.000 abstract 1
235000005985 organic acids Nutrition 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1
239000001301 oxygen Substances 0.000 abstract 1
229920006395 saturated elastomer Polymers 0.000 abstract 1
229910052717 sulfur Inorganic materials 0.000 abstract 1
125000004434 sulfur atom Chemical group 0.000 abstract 1
LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/44—Nitrogen atoms not forming part of a nitro radical
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/44—Nitrogen atoms not forming part of a nitro radical
- C07D233/52—Nitrogen atoms not forming part of a nitro radical with hetero atoms directly attached to said nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/06—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D239/08—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms directly attached in position 2
- C07D239/12—Nitrogen atoms not forming part of a nitro radical
- C07D239/16—Nitrogen atoms not forming part of a nitro radical acylated on said nitrogen atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

ES411341A 1972-02-08 1973-02-06 Procedimiento para la preparacion de compuestos heteroci- clicos sustituidos por un radical guanidinilideno. Expired ES411341A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE2205744A DE2205744A1 (de)	1972-02-08	1972-02-08	Neue durch einen guanidinylidenrest substituierte heterocyclen und verfahren zu ihrer herstellung

Publications (1)

Publication Number	Publication Date
ES411341A1 true ES411341A1 (es)	1976-03-16

Family

ID=5835294

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
ES411341A Expired ES411341A1 (es)	1972-02-08	1973-02-06	Procedimiento para la preparacion de compuestos heteroci- clicos sustituidos por un radical guanidinilideno.
ES424483A Expired ES424483A1 (es)	1972-02-08	1974-03-21	Procedimiento para la preparacion de compuestos heteroci- clicos sustituidos por un radical guanidilideno.

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
ES424483A Expired ES424483A1 (es)	1972-02-08	1974-03-21	Procedimiento para la preparacion de compuestos heteroci- clicos sustituidos por un radical guanidilideno.

Country Status (9)

Country	Link
JP (1)	JPS4891068A (fr)
AT (2)	AT324351B (fr)
AU (1)	AU472170B2 (fr)
BE (1)	BE795112A (fr)
DE (1)	DE2205744A1 (fr)
ES (2)	ES411341A1 (fr)
FR (1)	FR2181714B1 (fr)
GB (1)	GB1409768A (fr)
NL (1)	NL7301701A (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4211867A (en)	1976-03-19	1980-07-08	Mcneil Laboratories, Incorporated	Nitrogen heterocyclic carboximidamide compounds
NZ183570A (en) *	1976-03-19	1979-06-08	Mcneilab Inc	Heterocyclic guanidine derivatives, having anti-secretory and hypogliycaemic activity
US4266062A (en)	1978-09-18	1981-05-05	Mcneilab, Inc.	(1-Methyl-2-pyridinylidene) derivatives of guanidine
US4182865A (en) *	1978-09-18	1980-01-08	Mcneil Laboratories, Inc.	Diaza-cyclic derivatives of guanidine
CA1201119A (fr) *	1978-09-18	1986-02-25	Mcneilab, Inc.	Derives diaza-cycliques de la guanidine
US4414211A (en)	1978-09-18	1983-11-08	Mcneilab, Inc.	Heterocyclic derivatives of guanidine
AU5263779A (en) *	1978-11-29	1980-05-29	Beecham Group Limited	Derivatives of thiazolidin-2-ylidene and oxazolidin-2-ylidene with hypoglycaemic acitivity
DE3061396D1 (en)	1979-04-20	1983-01-27	Beecham Group Plc	Oxazoline and thiazoline derivatives, processes for their preparation and pharmaceutical compositions containing them
JPS55160764A (en) *	1979-05-29	1980-12-13	Ciba Geigy Ag	Guanidine* its manufacture and pharmaceutic medicine containing same
EP0020304A1 (fr) *	1979-05-29	1980-12-10	Ciba-Geigy Ag	Guanidines, procédé pour leur préparation, compositions pharmaceutiques les contenant et leur utilisation
EP0034002A3 (fr)	1980-01-22	1981-09-23	Beecham Group Plc	Dérivés de carboxamidine
DE102004008141A1 (de)	2004-02-19	2005-09-01	Abbott Gmbh & Co. Kg	Guanidinverbindungen und ihre Verwendung als Bindungspartner für 5-HT5-Rezeptoren
US10344002B2 (en)	2016-09-26	2019-07-09	Nusirt Sciences, Inc.	Compositions and methods for treating metabolic disorders

1972
- 1972-02-08 DE DE2205744A patent/DE2205744A1/de active Pending
1973
- 1973-02-06 ES ES411341A patent/ES411341A1/es not_active Expired
- 1973-02-07 GB GB607273A patent/GB1409768A/en not_active Expired
- 1973-02-07 AT AT1061673A patent/AT324351B/de not_active IP Right Cessation
- 1973-02-07 AT AT107173A patent/AT319268B/de not_active IP Right Cessation
- 1973-02-07 JP JP48015457A patent/JPS4891068A/ja active Pending
- 1973-02-07 NL NL7301701A patent/NL7301701A/xx unknown
- 1973-02-07 BE BE795112D patent/BE795112A/fr unknown
- 1973-02-07 AU AU51928/73A patent/AU472170B2/en not_active Expired
- 1973-02-08 FR FR7304496A patent/FR2181714B1/fr not_active Expired
1974
- 1974-03-21 ES ES424483A patent/ES424483A1/es not_active Expired

Also Published As

Publication number	Publication date
AT324351B (de)	1975-08-25
AU5192873A (en)	1974-08-08
BE795112A (fr)	1973-08-07
GB1409768A (en)	1975-10-15
AU472170B2 (en)	1976-05-20
JPS4891068A (fr)	1973-11-27
ES424483A1 (es)	1976-06-16
NL7301701A (fr)	1973-08-10
FR2181714B1 (fr)	1977-07-01
AT319268B (de)	1974-12-10
FR2181714A1 (fr)	1973-12-07
DE2205744A1 (de)	1973-08-09

Publication	Publication Date	Title
ES403503A1 (es)	1976-03-01	Procedimiento para la preparación de derivados de piperidina y su utilizacion como estabilizadores
ES391299A1 (es)	1975-11-01	Procedimiento para la preparacion de n-alil 2 - arilamino -imidazolinas (2) sustituidas.
ES411341A1 (es)	1976-03-16	Procedimiento para la preparacion de compuestos heteroci- clicos sustituidos por un radical guanidinilideno.
ES391026A1 (es)	1974-04-01	Procedimiento para la obtencion de benzonaftiridina.
ES417333A1 (es)	1976-02-16	Procedimiento de preparacion de nuevos derivados de (4'- (3''-indolil)piperidino)alcohil-arilcetonas.
ES420179A1 (es)	1976-05-01	Un procedimiento para la preparacion de iminas triciclicas con actividad farmacodinamica.
ES414343A1 (es)	1976-06-16	Procedimiento para la obtencion de derivados del acido prostanoico.
ES390163A1 (es)	1973-07-01	Procedimiento para la preparacion de amino-derivados de los acidos pirazolo (3,4-b) piridina-5-carboxilicos.
ES450381A1 (es)	1977-12-01	Procedimiento para preparar derivados de acido indanacetico.
ES423232A1 (es)	1976-05-01	Procedimiento para la preparacion de nuevas 2-fenilamino-i-midazolinas-(2) sustituidas.
ES419019A1 (es)	1976-06-16	Procedimiento para la preparacion de compuestos polici- clicos.
ES419739A1 (es)	1976-05-01	Procedimiento para la preparacion de 2-arilamino-imidazoli-nas (2) sustituidas.
ES395037A1 (es)	1974-08-16	Procedimiento para la obtencion de colorantes heterocicli- cos de dificil solubilidad.
ES433132A1 (es)	1977-02-16	Procedimiento para la obtencion de derivados de 1-fenoxi-3- amino-propan-2-ol.
ES385774A1 (es)	1973-11-16	Procedimiento para la preparacion de nuevas 2-(5-nitro-2- furil)-tieno (3,2-d) pirimidinas.
ES303109A1 (es)	1965-02-16	Procedimiento para la preparacion de imidazo quinazolinas y pirimido quinazolinas.
ES406768A1 (es)	1975-10-01	Procedimiento para la preparacion de nuevos derivados de indol.
ES414340A1 (es)	1976-05-16	Procedimiento de preparacion de derivados de la n-(m-tri- fluormetiltio-fenil-)-piperazina.
ES419740A1 (es)	1976-09-01	Procedimiento para la preparacion de 2-arilamino-imidazoli-nas-(2) sustituidas.
ES426874A1 (es)	1976-09-01	Procedimiento para la obtencion de nuevos derivados de dia-zepina.
ES357505A1 (es)	1970-03-16	Procedimiento para la preparacion de compuestos derivados del alcohol bencilico.
ES356529A1 (es)	1970-01-16	Procedimiento para la preparacion de nuevos acidos carboxi-licos heterociclicos.
ES417729A1 (es)	1977-01-01	Procedimiento para la preparacion de nuevos aminoetanoles.
ES385487A1 (es)	1973-08-16	Procedimiento para la preparacion de nuevos acidos carboxi-licos heterociclicos.
ES356528A1 (es)	1970-01-16	Procedimiento para la preparacion de nuevos acidos carboxi-licos heterociclicos.