ES405663A1 - Procedimiento para la obtencion de compuestos inhibidores de oxidasa de xantina. - Google Patents
Procedimiento para la obtencion de compuestos inhibidores de oxidasa de xantina.Info
- Publication number
- ES405663A1 ES405663A1 ES405663A ES405663A ES405663A1 ES 405663 A1 ES405663 A1 ES 405663A1 ES 405663 A ES405663 A ES 405663A ES 405663 A ES405663 A ES 405663A ES 405663 A1 ES405663 A1 ES 405663A1
- Authority
- ES
- Spain
- Prior art keywords
- pyrazola
- xanthine oxidase
- compounds useful
- oxidase inhibitors
- pyrimidine compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000003118 aryl group Chemical group 0.000 title 1
- 150000003230 pyrimidines Chemical class 0.000 title 1
- 239000003064 xanthine oxidase inhibitor Substances 0.000 title 1
- 108010093894 Xanthine oxidase Proteins 0.000 abstract 1
- 102100033220 Xanthine oxidase Human genes 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17219571A | 1971-08-16 | 1971-08-16 | |
| US261103A US3920652A (en) | 1971-08-16 | 1972-06-08 | Aromatic substituted pyrazola {8 1,5a{9 {0 pyrimidine compounds useful as xanthine oxidase inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES405663A1 true ES405663A1 (es) | 1976-01-16 |
Family
ID=26867834
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES405663A Expired ES405663A1 (es) | 1971-08-16 | 1972-08-08 | Procedimiento para la obtencion de compuestos inhibidores de oxidasa de xantina. |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US3920652A (es) |
| JP (1) | JPS4834899A (es) |
| AR (1) | AR193536A1 (es) |
| AT (1) | AT330780B (es) |
| BE (1) | BE786611A (es) |
| BG (1) | BG19806A3 (es) |
| DD (1) | DD99581A5 (es) |
| DE (1) | DE2236987A1 (es) |
| ES (1) | ES405663A1 (es) |
| FR (1) | FR2150771B1 (es) |
| GB (1) | GB1359563A (es) |
| HU (1) | HU167466B (es) |
| IE (1) | IE36629B1 (es) |
| IL (1) | IL39988A0 (es) |
| LU (1) | LU65892A1 (es) |
| MC (1) | MC937A1 (es) |
| NL (1) | NL7211011A (es) |
| RO (1) | RO63871A (es) |
| SU (1) | SU522800A3 (es) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4093617A (en) * | 1974-11-12 | 1978-06-06 | Icn Pharmaceuticals, Inc. | 3,5,7-Trisubstituted pyrazolo[1,5-a]pyrimidines |
| US4048184A (en) * | 1976-11-15 | 1977-09-13 | E. R. Squibb & Sons, Inc. | 6-Phenyl-2H-pyrazolo[3,4-b]pyridines |
| US4281000A (en) * | 1979-07-09 | 1981-07-28 | American Cyanamid Company | Substituted pyrazolo (1,5-a)pyrimidines and their use as anxiolytic agents |
| AU557300B2 (en) * | 1982-03-16 | 1986-12-18 | Farmitalia Carlo Erba S.P.A. | Substituted 1h-pyrazolo(1,5-alpha)pyrimidines and processes for their preparation |
| ZA831407B (en) * | 1982-03-25 | 1983-11-30 | Erba Farmitalia | Substituted ethenyl derivatives of 1h-pyrazolo(1,5-a)pyrimidine and process for their preparation |
| KR927003595A (ko) * | 1990-10-09 | 1992-12-18 | 오츠카 아키히코 | 피리미딘 유도체, 이의 제조방법 및 안드로겐 저해제 |
| AU667575B2 (en) * | 1992-10-20 | 1996-03-28 | Otsuka Pharmaceutical Co., Ltd. | Condensed pyrazole derivatives, method of manufacturing the same, and androgen inhibitor |
| KR100260292B1 (ko) * | 1995-09-28 | 2000-07-01 | 오쓰카 요시미쓰 | 진통제 |
| US6664261B2 (en) * | 1996-02-07 | 2003-12-16 | Neurocrine Biosciences, Inc. | Pyrazolopyrimidines as CRF receptor antagonists |
| US7094782B1 (en) | 1996-07-24 | 2006-08-22 | Bristol-Myers Squibb Company | Azolo triazines and pyrimidines |
| ES2294800T3 (es) * | 1996-07-24 | 2008-04-01 | Bristol-Myers Squibb Pharma Company | Azolo triazinas y pirimidinas. |
| US6191131B1 (en) | 1997-07-23 | 2001-02-20 | Dupont Pharmaceuticals Company | Azolo triazines and pyrimidines |
| US6124289A (en) * | 1996-07-24 | 2000-09-26 | Dupont Pharmaceuticals Co. | Azolo triazines and pyrimidines |
| US6313124B1 (en) | 1997-07-23 | 2001-11-06 | Dupont Pharmaceuticals Company | Tetrazine bicyclic compounds |
| US6060478A (en) * | 1996-07-24 | 2000-05-09 | Dupont Pharmaceuticals | Azolo triazines and pyrimidines |
| US6235741B1 (en) * | 1997-05-30 | 2001-05-22 | Merck & Co., Inc. | Angiogenesis inhibitors |
| AU1520699A (en) * | 1997-11-07 | 1999-05-31 | Johns Hopkins University, The | Methods for treatment of disorders of cardiac contractility |
| US6380203B1 (en) * | 1998-01-14 | 2002-04-30 | Merck & Co., Inc. | Angiogenesis inhibitors |
| WO2000059907A2 (en) * | 1999-04-06 | 2000-10-12 | Du Pont Pharmaceuticals Company | Pyrazolotriazines as crf antagonists |
| WO2000059908A2 (en) | 1999-04-06 | 2000-10-12 | Du Pont Pharmaceuticals Company | Pyrazolopyrimidines as crf antagonists |
| US6630476B2 (en) | 2000-07-07 | 2003-10-07 | Bristol-Myers Squibb Pharma Company | Pyrrolo [3,4-d] pyrimidines as corticotropin releasing factor (CRF) antagonists |
| DE112015002679T5 (de) | 2014-06-06 | 2017-04-20 | Siemens Medical Solutions Usa, Inc. | Gammakamera-totzeitbestimmung in echtzeit unter verwendung langlebiger radioisotope |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3048587A (en) * | 1960-10-17 | 1962-08-07 | Ortho Pharma Corp | 2-alkylamino-4-aminopyrimidine |
| US3296268A (en) * | 1965-10-19 | 1967-01-03 | Searle & Co | 3-cyanoethyl-2-oxo-5-phenyl [1, 5-a] pyrimidines |
-
0
- BE BE786611D patent/BE786611A/xx unknown
-
1972
- 1972-06-08 US US261103A patent/US3920652A/en not_active Expired - Lifetime
- 1972-07-25 IL IL39988A patent/IL39988A0/xx unknown
- 1972-07-27 DE DE2236987A patent/DE2236987A1/de active Pending
- 1972-08-02 MC MC1005A patent/MC937A1/xx unknown
- 1972-08-04 AT AT677372A patent/AT330780B/de not_active IP Right Cessation
- 1972-08-07 GB GB3680472A patent/GB1359563A/en not_active Expired
- 1972-08-08 ES ES405663A patent/ES405663A1/es not_active Expired
- 1972-08-08 AR AR243489A patent/AR193536A1/es active
- 1972-08-08 IE IE1107/72A patent/IE36629B1/xx unknown
- 1972-08-11 LU LU65892A patent/LU65892A1/xx unknown
- 1972-08-11 FR FR7229107A patent/FR2150771B1/fr not_active Expired
- 1972-08-11 NL NL7211011A patent/NL7211011A/xx unknown
- 1972-08-14 BG BG021195A patent/BG19806A3/xx unknown
- 1972-08-14 DD DD165054A patent/DD99581A5/xx unknown
- 1972-08-15 HU HUIE526A patent/HU167466B/hu unknown
- 1972-08-15 SU SU1821375A patent/SU522800A3/ru active
- 1972-08-16 RO RO7200071971A patent/RO63871A/ro unknown
- 1972-08-16 JP JP47082059A patent/JPS4834899A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| IL39988A0 (en) | 1972-09-28 |
| ATA677372A (de) | 1975-10-15 |
| IE36629L (en) | 1973-02-16 |
| JPS4834899A (es) | 1973-05-22 |
| AT330780B (de) | 1976-07-26 |
| AR193536A1 (es) | 1973-04-30 |
| RO63871A (fr) | 1979-01-15 |
| DE2236987A1 (de) | 1973-03-01 |
| FR2150771A1 (es) | 1973-04-13 |
| IE36629B1 (en) | 1977-01-19 |
| FR2150771B1 (es) | 1976-05-21 |
| SU522800A3 (ru) | 1976-07-25 |
| US3920652A (en) | 1975-11-18 |
| BG19806A3 (bg) | 1975-10-10 |
| MC937A1 (fr) | 1973-08-10 |
| BE786611A (fr) | 1973-01-22 |
| NL7211011A (es) | 1973-02-20 |
| DD99581A5 (es) | 1973-08-12 |
| HU167466B (es) | 1975-10-28 |
| GB1359563A (en) | 1974-07-10 |
| LU65892A1 (es) | 1973-01-15 |
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