ES397385A1 - Procedure for preparing steroids of the alcohiled stress series in the b ring (Machine-translation by Google Translate, not legally binding) - Google Patents
Procedure for preparing steroids of the alcohiled stress series in the b ring (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES397385A1 ES397385A1 ES397385A ES397385A ES397385A1 ES 397385 A1 ES397385 A1 ES 397385A1 ES 397385 A ES397385 A ES 397385A ES 397385 A ES397385 A ES 397385A ES 397385 A1 ES397385 A1 ES 397385A1
- Authority
- ES
- Spain
- Prior art keywords
- group
- translation
- procedure
- ring
- machine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
Abstract
Procedure for preparing steroids of the estrano series alcoholized in ring B, characterized in that new compounds of general formula are prepared: **(See formula)** where R1 is H2 or a keto group, R2 is a lower alcohol group of 1 to 4 C atoms, R3 is O or beta-OX (alpha-Y), where X is hydrogen, an acyl group or an ether group, and Y is hydrogen or an alcoholic, alkenyl or lower alkynyl group of 1 to 6 C atoms, starting from a compound of the formula: **(See formula)** where R2 and R3 have the aforementioned meanings, separating the 5alpha-hydroxyl group by dehydration, to form a double bond between carbon atoms 4 and 5, and isomerizing the 6-beta-methyl group to a 6-alpha-methyl group, after which the 3-keto group can be removed, preferably by thioketalization and reduction of the 3-thioketal substituent, and/or by introducing the substituents at position 17, if they are not already present in the starting products, in a manner known per se. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL7017428A NL7017428A (en) | 1970-11-28 | 1970-11-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES397385A1 true ES397385A1 (en) | 1974-05-16 |
Family
ID=19811666
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES397385A Expired ES397385A1 (en) | 1970-11-28 | 1971-11-26 | Procedure for preparing steroids of the alcohiled stress series in the b ring (Machine-translation by Google Translate, not legally binding) |
Country Status (7)
| Country | Link |
|---|---|
| AU (1) | AU3545671A (en) |
| BE (1) | BE775052A (en) |
| DE (1) | DE2158837A1 (en) |
| ES (1) | ES397385A1 (en) |
| FR (1) | FR2115454A1 (en) |
| NL (1) | NL7017428A (en) |
| ZA (1) | ZA717307B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3909770A1 (en) * | 1989-03-21 | 1990-09-27 | Schering Ag | METHOD FOR PRODUCING 3-DESOXY-4-EN STEROIDS |
-
1970
- 1970-11-28 NL NL7017428A patent/NL7017428A/xx unknown
-
1971
- 1971-11-01 ZA ZA717307A patent/ZA717307B/en unknown
- 1971-11-08 AU AU35456/71A patent/AU3545671A/en not_active Expired
- 1971-11-08 BE BE775052A patent/BE775052A/en unknown
- 1971-11-26 FR FR7142546A patent/FR2115454A1/en not_active Withdrawn
- 1971-11-26 ES ES397385A patent/ES397385A1/en not_active Expired
- 1971-11-26 DE DE19712158837 patent/DE2158837A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| FR2115454A1 (en) | 1972-07-07 |
| DE2158837A1 (en) | 1972-05-31 |
| AU3545671A (en) | 1973-05-17 |
| BE775052A (en) | 1972-03-01 |
| NL7017428A (en) | 1972-05-30 |
| ZA717307B (en) | 1972-07-26 |
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