ES390606A1 - Procedure to obtain a total ocular globe extract. (Machine-translation by Google Translate, not legally binding) - Google Patents
Procedure to obtain a total ocular globe extract. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES390606A1 ES390606A1 ES390606A ES390606A ES390606A1 ES 390606 A1 ES390606 A1 ES 390606A1 ES 390606 A ES390606 A ES 390606A ES 390606 A ES390606 A ES 390606A ES 390606 A1 ES390606 A1 ES 390606A1
- Authority
- ES
- Spain
- Prior art keywords
- extract
- ocular
- water
- globules
- carried out
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000284 extract Substances 0.000 title abstract 10
- 238000000034 method Methods 0.000 title abstract 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 3
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 abstract 2
- 230000001464 adherent effect Effects 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 2
- 238000000605 extraction Methods 0.000 abstract 2
- 238000001914 filtration Methods 0.000 abstract 2
- 238000000926 separation method Methods 0.000 abstract 2
- 102000009027 Albumins Human genes 0.000 abstract 1
- 108010088751 Albumins Proteins 0.000 abstract 1
- 208000035404 Autolysis Diseases 0.000 abstract 1
- 241000283690 Bos taurus Species 0.000 abstract 1
- 206010057248 Cell death Diseases 0.000 abstract 1
- 239000006096 absorbing agent Substances 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 238000013019 agitation Methods 0.000 abstract 1
- 239000012675 alcoholic extract Substances 0.000 abstract 1
- 238000005119 centrifugation Methods 0.000 abstract 1
- 239000012141 concentrate Substances 0.000 abstract 1
- 230000001143 conditioned effect Effects 0.000 abstract 1
- 230000003750 conditioning effect Effects 0.000 abstract 1
- 239000004744 fabric Substances 0.000 abstract 1
- 235000011837 pasties Nutrition 0.000 abstract 1
- 239000013049 sediment Substances 0.000 abstract 1
- 230000028043 self proteolysis Effects 0.000 abstract 1
- 230000001954 sterilising effect Effects 0.000 abstract 1
- RTKIYNMVFMVABJ-UHFFFAOYSA-L thimerosal Chemical compound [Na+].CC[Hg]SC1=CC=CC=C1C([O-])=O RTKIYNMVFMVABJ-UHFFFAOYSA-L 0.000 abstract 1
- 238000005406 washing Methods 0.000 abstract 1
Landscapes
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Abstract
Procedure to obtain a total extract of ocular globule, from the eye of bovines, destined to the ophthalmological therapeutics and as a general stimulant, which is prepared taking the ocular globules, separating the adherent tissues, crushing the ocular globules, effecting its extraction by means of of alcohol, filtering the obtained extract of the picadillo, concentrating and obtaining a dry extract, dissolving, conditioning and sterilizing the extract, characterized in that in order to obtain a product enriched in biologically active substances and with increased specificity, the ocular globules are submitted, after separation of adherent tissues, to a water wash with merthiolate in a concentration of 1: 10,000 and to a process of autolysis for 4 days, at a temperature comprised between 0 and + 4ºc, the alcoholic extract is obtained with 2 ml of officinal alcohol per gram of ocular globule mince, the extraction being carried out n first by mechanical agitation for 6 hours followed by a period of 24 hours, the filtration of the crushed extract is carried out firstly in press, then by a dense cloth, operation that is repeated 4-5 times, by paper -filter, the concentration of the extract is carried out to dryness partially under vacuum at a temperature not to exceed 52ºC to remove alcohol and a part of water, until obtaining a pasty consistency and then after mixing the concentrate with celite. 10%, at 90-l00ºc, to dryness, finished by removing traces of water in the desiccator, in the presence of compact absorbers, after which the dry extract, controlled for the absence of albumins, dissolves in water in several stages with separation in each stage of the sediment by centrifugation until the complete washing of the celite, finally the extract is conditioned as a medicine that is made by calculating the correction factor 0.8 the equivalent of 1 ml of extract per gram of forcemeat. (Machine-translation by Google Translate, not legally binding)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES390606A ES390606A1 (en) | 1971-04-26 | 1971-04-26 | Procedure to obtain a total ocular globe extract. (Machine-translation by Google Translate, not legally binding) |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES390606A ES390606A1 (en) | 1971-04-26 | 1971-04-26 | Procedure to obtain a total ocular globe extract. (Machine-translation by Google Translate, not legally binding) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES390606A1 true ES390606A1 (en) | 1973-06-16 |
Family
ID=8458273
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES390606A Expired ES390606A1 (en) | 1971-04-26 | 1971-04-26 | Procedure to obtain a total ocular globe extract. (Machine-translation by Google Translate, not legally binding) |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES390606A1 (en) |
-
1971
- 1971-04-26 ES ES390606A patent/ES390606A1/en not_active Expired
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