ES380780A1 - Procedure for the preparation of triazaespirodecanoditionas. (Machine-translation by Google Translate, not legally binding) - Google Patents
Procedure for the preparation of triazaespirodecanoditionas. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES380780A1 ES380780A1 ES380780A ES380780A ES380780A1 ES 380780 A1 ES380780 A1 ES 380780A1 ES 380780 A ES380780 A ES 380780A ES 380780 A ES380780 A ES 380780A ES 380780 A1 ES380780 A1 ES 380780A1
- Authority
- ES
- Spain
- Prior art keywords
- triazaespirodecanoditionas
- translation
- procedure
- preparation
- machine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title 1
- NLXLAEXVIDQMFP-UHFFFAOYSA-N Ammonia chloride Chemical compound [NH4+].[Cl-] NLXLAEXVIDQMFP-UHFFFAOYSA-N 0.000 abstract 2
- QGJOPFRUJISHPQ-UHFFFAOYSA-N Carbon disulfide Chemical compound S=C=S QGJOPFRUJISHPQ-UHFFFAOYSA-N 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- -1 alkali metal cyanide Chemical class 0.000 abstract 1
- 235000019270 ammonium chloride Nutrition 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 238000009835 boiling Methods 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 230000001747 exhibiting effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Novel compounds I where R is C 1 to C 8 alkyl, aryl or cycloalkyl and R1 and R2 are H or C 1 to C 8 alkyl, are made by reacting II with an alkali metal cyanide, ammonium chloride and carbon disulphide at between ambient and the boiling temperature of the mixture for 2 to 24 hours, optionally in the presence of solvent the products obtained (R 1 and R 2 are H) may subsequently be alkylated. Pharmaceutical preparations exhibiting antiinflammatory action contain I as active ingredient administration may be orally.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT1980169 | 1969-07-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES380780A1 true ES380780A1 (en) | 1972-09-16 |
Family
ID=11161321
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES380780A Expired ES380780A1 (en) | 1969-07-18 | 1970-06-15 | Procedure for the preparation of triazaespirodecanoditionas. (Machine-translation by Google Translate, not legally binding) |
Country Status (15)
| Country | Link |
|---|---|
| JP (1) | JPS4932541B1 (en) |
| AT (1) | AT297729B (en) |
| BE (1) | BE751650A (en) |
| BR (1) | BR6914929D0 (en) |
| CH (1) | CH511244A (en) |
| DE (1) | DE2031359C3 (en) |
| ES (1) | ES380780A1 (en) |
| FI (1) | FI50244C (en) |
| FR (1) | FR2059529B1 (en) |
| GB (1) | GB1265134A (en) |
| IL (1) | IL34702A (en) |
| NL (1) | NL142682B (en) |
| NO (1) | NO125850B (en) |
| SE (1) | SE358394B (en) |
| ZA (1) | ZA703809B (en) |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3542729A (en) * | 1968-03-19 | 1970-11-24 | Sankyo Co | Stabilization of synthetic polymers |
-
1969
- 1969-12-10 BR BR214929/69A patent/BR6914929D0/en unknown
-
1970
- 1970-06-03 GB GB1265134D patent/GB1265134A/en not_active Expired
- 1970-06-04 ZA ZA703809A patent/ZA703809B/en unknown
- 1970-06-08 BE BE751650D patent/BE751650A/en unknown
- 1970-06-09 IL IL34702A patent/IL34702A/en unknown
- 1970-06-15 ES ES380780A patent/ES380780A1/en not_active Expired
- 1970-06-18 NO NO2368/70A patent/NO125850B/no unknown
- 1970-06-25 DE DE2031359A patent/DE2031359C3/en not_active Expired
- 1970-07-02 FI FI701872A patent/FI50244C/en active
- 1970-07-03 AT AT603170A patent/AT297729B/en not_active IP Right Cessation
- 1970-07-15 NL NL707010481A patent/NL142682B/en unknown
- 1970-07-16 CH CH1093670A patent/CH511244A/en not_active IP Right Cessation
- 1970-07-16 JP JP45062507A patent/JPS4932541B1/ja active Pending
- 1970-07-17 SE SE09952/70A patent/SE358394B/xx unknown
- 1970-07-17 FR FR7026481A patent/FR2059529B1/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FI50244B (en) | 1975-09-30 |
| FR2059529A1 (en) | 1971-06-04 |
| SE358394B (en) | 1973-07-30 |
| NL142682B (en) | 1974-07-15 |
| CH511244A (en) | 1971-08-15 |
| DE2031359A1 (en) | 1971-02-04 |
| ZA703809B (en) | 1971-01-27 |
| IL34702A0 (en) | 1970-08-19 |
| DE2031359B2 (en) | 1975-02-20 |
| FR2059529B1 (en) | 1973-12-21 |
| AT297729B (en) | 1972-04-10 |
| JPS4932541B1 (en) | 1974-08-31 |
| BR6914929D0 (en) | 1973-04-19 |
| FI50244C (en) | 1976-01-12 |
| NO125850B (en) | 1972-11-13 |
| NL7010481A (en) | 1971-01-20 |
| DE2031359C3 (en) | 1975-10-02 |
| IL34702A (en) | 1972-12-29 |
| GB1265134A (en) | 1972-03-01 |
| BE751650A (en) | 1970-11-16 |
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