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ES376787A1 - Enzymatic products which optimise the viscosity of mucuses and their applications - Google Patents

Enzymatic products which optimise the viscosity of mucuses and their applications

Info

Publication number
ES376787A1
ES376787A1 ES376787A ES376787A ES376787A1 ES 376787 A1 ES376787 A1 ES 376787A1 ES 376787 A ES376787 A ES 376787A ES 376787 A ES376787 A ES 376787A ES 376787 A1 ES376787 A1 ES 376787A1
Authority
ES
Spain
Prior art keywords
viscosity
mucus
products
chymotrypsin
enzymatic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES376787A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Instituto de Farmacologia Espanola SL Fundacion Marques de Urquijo
Original Assignee
Instituto de Farmacologia Espanola SL Fundacion Marques de Urquijo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Instituto de Farmacologia Espanola SL Fundacion Marques de Urquijo filed Critical Instituto de Farmacologia Espanola SL Fundacion Marques de Urquijo
Publication of ES376787A1 publication Critical patent/ES376787A1/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/189Enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Husbandry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Fodder In General (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Procedure for the preparation of enzymatic proteolytic products, which improve the viscosity of the intestinal, bronchial and cervical mucus in vivo, from a microorganism, characterized in that the fermentation of said microorganism is slowed down since the viscosity reduction to 1 g of intestinal mucus at 37ºC in vitro per 0.1 ml of a 250 AU solution of enzyme products obtained, this being between, at the maximum, the reduction due to 250 UA of pure chymotrypsin plus 5% and, at a minimum, the reduction, due to 250 UA of pure chymotrypsin minus 5%, the decrease in the viscosity of the mucus being indicated in percentage in relation to the viscosity of the aforementioned non-degraded mucus and being for the intestinal mucus of the pig or calf, respectively of 60% for trypsin and 40% for chymotrypsin after 30 min of enzymatic degradation, the base to be selected, and should also provide insensitive products bles to trypsic inhibitors and why the aforementioned enzymatic products are capable of being purified. (Machine-translation by Google Translate, not legally binding)
ES376787A 1969-02-21 1970-02-21 Enzymatic products which optimise the viscosity of mucuses and their applications Expired ES376787A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB961969 1969-02-21

Publications (1)

Publication Number Publication Date
ES376787A1 true ES376787A1 (en) 1972-05-01

Family

ID=9875487

Family Applications (1)

Application Number Title Priority Date Filing Date
ES376787A Expired ES376787A1 (en) 1969-02-21 1970-02-21 Enzymatic products which optimise the viscosity of mucuses and their applications

Country Status (17)

Country Link
AT (1) AT297635B (en)
BE (1) BE745697A (en)
CH (1) CH513978A (en)
CS (1) CS151008B2 (en)
DE (1) DE2006514C3 (en)
DK (1) DK132666C (en)
ES (1) ES376787A1 (en)
FR (1) FR2034559B1 (en)
GB (1) GB1307516A (en)
IE (1) IE33729B1 (en)
IL (1) IL33904A (en)
LU (1) LU60376A1 (en)
NL (1) NL170965C (en)
OA (1) OA03218A (en)
RO (1) RO58428A2 (en)
SE (1) SE374389B (en)
YU (1) YU35032B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2600340A1 (en) * 1986-06-20 1987-12-24 Hooremam Michel PROCESS FOR THE PRODUCTION OF A NEW PROTEOLYTIC COMPLEX STIMULATING THE ACTIVITY OF PANCREAS AND ITS APPLICATIONS IN ZOOTECHNY
KR100563523B1 (en) * 1996-04-05 2006-07-06 미켈 호레만 Pharmaceuticals to optimize mucus viscosity and stimulate intestinal function
DE19724458A1 (en) * 1997-06-10 1998-12-24 Mucos Pharma Gmbh & Co Use of proteolytic enzymes e.g., trypsin, bromelain or papain
FR2998450A1 (en) * 2012-11-26 2014-05-30 Dominique Hooreman USE OF AN ENZYMATIC COMPLEX IN FEEDING ANIMAL BREEDING ANIMALS

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1133579A (en) * 1966-03-09 1968-11-13 Shionogi & Co Process for preparing proteases and enzymatic composition prepared thereby

Also Published As

Publication number Publication date
CS151008B2 (en) 1973-09-17
RO58428A2 (en) 1975-06-25
AT297635B (en) 1972-04-10
FR2034559A1 (en) 1970-12-11
NL170965C (en) 1983-01-17
FR2034559B1 (en) 1974-03-22
YU35032B (en) 1980-06-30
DE2006514A1 (en) 1970-09-10
NL170965B (en) 1982-08-16
DK132666B (en) 1976-01-19
YU42270A (en) 1979-12-31
IE33729L (en) 1970-08-21
DE2006514C3 (en) 1978-05-24
DE2006514B2 (en) 1977-09-29
CH513978A (en) 1971-10-15
DK132666C (en) 1976-06-14
GB1307516A (en) 1973-02-21
IE33729B1 (en) 1974-10-16
IL33904A0 (en) 1970-04-20
OA03218A (en) 1970-12-15
SE374389B (en) 1975-03-03
IL33904A (en) 1974-03-14
LU60376A1 (en) 1970-04-22
BE745697A (en) 1970-07-16
NL7002466A (en) 1970-08-25

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