ES364721A1 - Procedure for the preparation of new derivatives of paminoalquil-bencensulfonamida. (Machine-translation by Google Translate, not legally binding) - Google Patents

Abstract

Procedure for the preparation of new derivatives of p-aminoalkyl-benzenesulfonamide of the general formula I **(See formula)** in which m means 2 or 3, R1 means an alkyl group with 12 carbon atoms at most, an alkenyl group with 3-5 carbon atoms, a cycloalkyl or cycloalkenyl group with 7 carbon atoms at most or a phenylalkyl group with 9 carbon atoms at most, R2 means hydrogen or an alkyl group with 2 carbon atoms at most, R3 means hydrogen, an alkyl or chloroalkyl group with at most 7 carbon atoms, an alkynyl group with at most 5 carbon atoms, a cycloalkyl or cycloalkenyl group with at most 8 carbon atoms, a phenyl group or a group phenylalkyl or phenylalkyl with 10 carbon atoms at most, where the phenyl group present as R3 or R3, may be substituted one to three times by halogen up to atomic number 35, trifluoromethyl groups, alkyl groups with 4 atoms of carbon at most, hydroxylic, alkoxy or 2-carbon-alkylthio groups at most, and R4 means hydrogen or the methyl group, and its addition salts with inorganic or organic acids, characterized in that a functional derivative suitable for reaction of a sulfonic acid of the general formula II, **(See formula)** in which m, R3 and R4 have the significance indicated under formula I, it is reacted with a compound of the general formula III **(See formula)** in which R1 and R3 have the significance indicated under general formula I, and the reaction product is optionally transformed with an inorganic or organic acid into an addition salt. (Machine-translation by Google Translate, not legally binding)