ES339539A1 - Procedure for the production of derivatives of isoquinoline. (Machine-translation by Google Translate, not legally binding)
- Google Patents
Procedure for the production of derivatives of isoquinoline. (Machine-translation by Google Translate, not legally binding)
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Sandoz AG
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Sandoz AG
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Publication of ES339539A1publicationCriticalpatent/ES339539A1/en
Process for the production of isoquinoline derivatives of formula I, **(See formula)** wherein R1 signifies a hydrogen atom or a methyl radical, each R2 signifies a hydrogen atom or a lower alkoxy radical, or together signifies a methylenedioxy radical, and each of the two symbols X signifies a hydrogen atom or together they signify a second carbon-nitrogen bond, characterized in that an amide of formula II is cyclized, **(See formula)** wherein R1 and R2 have the meanings indicated above, by treatment with an acidic water-separating condensation agent according to Bischler-Napieralski, and when a compound I is desired, in which each of the two symbols X means a hydrogen atom, the double bond at position 1-2 of the resulting compound I is reduced, where the two symbols X together signify a second carbon-nitrogen bond. (Machine-translation by Google Translate, not legally binding)
ES339539A1966-04-221967-04-20Procedure for the production of derivatives of isoquinoline. (Machine-translation by Google Translate, not legally binding)
ExpiredES339539A1
(en)
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