ES323695A1 - Procedure for the production of spiro-succinimide derivatives. (Machine-translation by Google Translate, not legally binding) - Google Patents
Procedure for the production of spiro-succinimide derivatives. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES323695A1 ES323695A1 ES0323695A ES323695A ES323695A1 ES 323695 A1 ES323695 A1 ES 323695A1 ES 0323695 A ES0323695 A ES 0323695A ES 323695 A ES323695 A ES 323695A ES 323695 A1 ES323695 A1 ES 323695A1
- Authority
- ES
- Spain
- Prior art keywords
- signifies
- formula
- spiro
- translation
- production
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229940053198 antiepileptics succinimide derivative Drugs 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- -1 aralkyl radical Chemical class 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- WODIALSWFWKWMM-UHFFFAOYSA-N 2,8-diazaspiro[4.5]decane-1,3-dione Chemical compound O=C1NC(=O)CC11CCNCC1 WODIALSWFWKWMM-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 239000011230 binding agent Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- WCYWZMWISLQXQU-UHFFFAOYSA-N methyl Chemical compound [CH3] WCYWZMWISLQXQU-UHFFFAOYSA-N 0.000 abstract 1
- 150000003254 radicals Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyrrole Compounds (AREA)
Abstract
Process for the production of spiro-succinimide derivatives of 10,11-dihydro-5H-dibenzo [b, f] acepine of formula I, ** (See formula) ** wherein R 1 signifies an alkyl or lower aralkyl radical, R 2 signifies a hydrogen atom or a lower alkyl radical, and R 3 signifies a hydrogen atom or the methyl radical, characterized in that a compound of the formula is heated up to 120-220º C. II, ** (See formula) ** wherein R3 has the meaning indicated above, and X signifies the acid radical of a reactive ester, in the presence of an acid-binding agent with a 2,8-diazaspiro [4,5] decan-1,3-dione of formula III, ** (See formula) ** wherein R1 and R2 have the meanings indicated above. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH294565 | 1965-03-03 | ||
| CH1475865 | 1965-10-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES323695A1 true ES323695A1 (en) | 1967-01-16 |
Family
ID=25691785
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES0323695A Expired ES323695A1 (en) | 1965-03-03 | 1966-03-01 | Procedure for the production of spiro-succinimide derivatives. (Machine-translation by Google Translate, not legally binding) |
Country Status (5)
| Country | Link |
|---|---|
| AT (1) | AT258299B (en) |
| BE (1) | BE677217A (en) |
| ES (1) | ES323695A1 (en) |
| FR (1) | FR1470513A (en) |
| NL (1) | NL6602482A (en) |
-
1966
- 1966-02-25 NL NL6602482A patent/NL6602482A/xx unknown
- 1966-03-01 ES ES0323695A patent/ES323695A1/en not_active Expired
- 1966-03-01 BE BE677217D patent/BE677217A/xx unknown
- 1966-03-01 AT AT190966A patent/AT258299B/en active
- 1966-03-02 FR FR51672A patent/FR1470513A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FR1470513A (en) | 1967-02-24 |
| BE677217A (en) | 1966-09-01 |
| NL6602482A (en) | 1966-09-05 |
| AT258299B (en) | 1967-11-10 |
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