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ES303109A1 - Procedure for the preparation of imidazo quinazolinas and pirimido quinazolinas. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the preparation of imidazo quinazolinas and pirimido quinazolinas. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES303109A1
ES303109A1 ES0303109A ES303109A ES303109A1 ES 303109 A1 ES303109 A1 ES 303109A1 ES 0303109 A ES0303109 A ES 0303109A ES 303109 A ES303109 A ES 303109A ES 303109 A1 ES303109 A1 ES 303109A1
Authority
ES
Spain
Prior art keywords
formula
quinazolinas
imidazo
translation
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0303109A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wander AG
Original Assignee
Wander AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wander AG filed Critical Wander AG
Publication of ES303109A1 publication Critical patent/ES303109A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Procedure for the preparation of new derivatives of 2,3,5,6-tetrahydro-imidazo [1,2-c] quinazoline and 2,3,6,7-tetrahydro-4H-pyrimido [1,2-c] quinazoline of the formula: ** (See formula) ** meaning R alkylene with 2 or 3 carbon atoms, R1 cycloalkyl with 5 to 7 carbon atoms, phenyl, benzyl, furyl, thienyl or phenyl or benzyl substituted by halogen, trifluoromethyl, low alkyl, low alkoxy or low alkylthio, and R2 hydrogen or lower alkyl, as well as acid addition salts thereof, characterized in that it is reacted either a) an o- (2-imidazolin-2-yl) aniline respectively o- (1,4,5,6-tetrahydropyrimidin-2-yl) aniline of the formula: ** (See formula) ** R and R2 having the indicated meaning, respectively an acid addition salt thereof, with an aldehyde of the formula R1 - CHO (III) having R1 the indicated meaning, or because: b) it is a compound of the formula: ** (See formula) ** having R and R1 the aforementioned meaning, with a mild reduction medium, optionally with subsequent introduction of an alkyl group R2; the reaction product being obtained as a base or in the form of an acid addition salt. (Machine-translation by Google Translate, not legally binding)
ES0303109A 1963-08-16 1964-08-13 Procedure for the preparation of imidazo quinazolinas and pirimido quinazolinas. (Machine-translation by Google Translate, not legally binding) Expired ES303109A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1013563A CH422807A (en) 1963-08-16 1963-08-16 Process for the preparation of imidazo and pyrimido quinazolines

Publications (1)

Publication Number Publication Date
ES303109A1 true ES303109A1 (en) 1965-02-16

Family

ID=4359739

Family Applications (1)

Application Number Title Priority Date Filing Date
ES0303109A Expired ES303109A1 (en) 1963-08-16 1964-08-13 Procedure for the preparation of imidazo quinazolinas and pirimido quinazolinas. (Machine-translation by Google Translate, not legally binding)

Country Status (11)

Country Link
AT (2) AT249066B (en)
BE (1) BE651920A (en)
BR (1) BR6461683D0 (en)
CH (1) CH422807A (en)
DE (1) DE1470432A1 (en)
DK (1) DK108394C (en)
ES (1) ES303109A1 (en)
FR (1) FR3828M (en)
GB (1) GB1042299A (en)
NL (1) NL6409191A (en)
SE (2) SE311912B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4282226A (en) * 1978-04-26 1981-08-04 E. R. Squibb & Sons, Inc. Thioxopyrazolo[1,5-c]quinazoline derivatives, anti-allergic compositions and methods for treating allergic conditions by parenteral administration, aerosol or insufflation
GR78233B (en) * 1980-08-15 1984-09-26 Ciba Geigy Ag
US4469868A (en) * 1982-05-24 1984-09-04 Warner-Lambert Company Alkylimidazo[1,2-c]pyrazolo[3,4-e]pyrimidines

Also Published As

Publication number Publication date
DK108394C (en) 1967-12-04
SE341010B (en) 1971-12-13
CH422807A (en) 1966-10-31
GB1042299A (en) 1966-09-14
AT249068B (en) 1966-09-26
DE1470432A1 (en) 1969-12-18
BR6461683D0 (en) 1973-07-17
NL6409191A (en) 1965-02-17
AT249066B (en) 1966-09-26
FR3828M (en) 1966-01-10
SE311912B (en) 1969-06-30
BE651920A (en) 1965-02-17

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