ES291879A1 - Procedure for the manufacture of new basic 1,3-dioxanes and their salts (Machine-translation by Google Translate, not legally binding) - Google Patents
Procedure for the manufacture of new basic 1,3-dioxanes and their salts (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES291879A1 ES291879A1 ES0291879A ES291879A ES291879A1 ES 291879 A1 ES291879 A1 ES 291879A1 ES 0291879 A ES0291879 A ES 0291879A ES 291879 A ES291879 A ES 291879A ES 291879 A1 ES291879 A1 ES 291879A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- dioxanes
- meaning
- salts
- see
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000003839 salts Chemical class 0.000 title abstract 4
- 150000000093 1,3-dioxanes Chemical class 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- -1 benzhydryl group Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- IXTNDEVVXTYVHI-UHFFFAOYSA-N 1,4-dioxan-2-amine Chemical compound NC1COCCO1 IXTNDEVVXTYVHI-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 150000001299 aldehydes Chemical class 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000004429 atom Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 150000002012 dioxanes Chemical class 0.000 abstract 1
- 125000000532 dioxanyl group Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
- 150000002576 ketones Chemical class 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Process for the manufacture of new basic 1,3-dioxanes and their salts of the general formula I ** (See formula) ** wherein R 1 is hydrogen or a lower alkyl radical, A a branched or straight-chain alkylene radical, X a benzhydryl group or a 1-phenylcyclohexyl group, while R 2 and R 3 represent hydrogen, aryl or alkyl radicals, which may be also be combined with the C2 atom of the dioxane ring forming a cycloalkyl ring, and its salts, characterized in that a) to 5-amino-dioxanes- (1,3) of the formula II ** (See formula) ** wherein R1, R2 and R3 have the above meaning, they are reacted with halogenated compounds of the formula XA-Hal (meaning of X and A as before), or conversely of this reaction, 5-halogen- dioxanes of formula III ** (See formula) ** wherein R2 and R3 have the above meaning, with an amine of the formula R1-NH-A-X (meaning R1, A and X as indicated above), or b) aldehydes of the formula IV are reduced ** (See formula) ** wherein X has the meaning indicated above and B is an alkylene chain shortened by 1 C atom against A, or the corresponding ketones in the presence of an aminodioxane of the formula II (R1 = H), and optionally subsequently (R1 = lower alkyl), or c) an amide of formula V is reduced ** (See formula) ** wherein R1, R2, R3, X and B have the meaning indicated above, after which, if desired, the dioxanes of formula I obtained are commonly transferred to their salts. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE291879X | 1962-09-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES291879A1 true ES291879A1 (en) | 1964-01-01 |
Family
ID=38570514
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES0291879A Expired ES291879A1 (en) | 1962-09-29 | 1963-09-21 | Procedure for the manufacture of new basic 1,3-dioxanes and their salts (Machine-translation by Google Translate, not legally binding) |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES291879A1 (en) |
-
1963
- 1963-09-21 ES ES0291879A patent/ES291879A1/en not_active Expired
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