ES274335A1 - Preparation of derivatives of 1, 4-benzodioxan - Google Patents
Preparation of derivatives of 1, 4-benzodioxanInfo
- Publication number
- ES274335A1 ES274335A1 ES0274335A ES274335A ES274335A1 ES 274335 A1 ES274335 A1 ES 274335A1 ES 0274335 A ES0274335 A ES 0274335A ES 274335 A ES274335 A ES 274335A ES 274335 A1 ES274335 A1 ES 274335A1
- Authority
- ES
- Spain
- Prior art keywords
- general formula
- amino group
- group
- nr1r2
- inorganic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Process for the preparation of new 1,4-benzodioxane compounds of the general formula I ** (See formula) ** in which NR1R2 means the amino group or a mono- or bi-substituted aliphatic or heterocyclic amino group, R means hydrogen or a lower alkyl radical, Y means hydrogen, a halogen atom, a hydroxyl group, a lower alkyl group or a lower alkoxy group and n is 1,2,3,4 or 5, as well as its non-toxic salts with inorganic or organic acids, characterized in that a nitrile of the general formula II ** (See formula) ** in which R, Y and n have the meaning already expressed, is reduced catalytically or chemically to an amine of the general formula III ** (See formula) ** wherein R, Y and n have the meaning already expressed, and, if desired, the free amino group, -NH2, is converted in a manner already known per se to a substituted amino group, -NR1R2, and likewise, if desired, the compound obtained, of the general formula I, is converted into a salt with an inorganic or organic acid. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US148704A US3149108A (en) | 1961-10-30 | 1961-10-30 | Preparation of derivatives of 1, 4-benzodioxan |
Publications (1)
Publication Number | Publication Date |
---|---|
ES274335A1 true ES274335A1 (en) | 1962-06-01 |
Family
ID=22526973
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES0274335A Expired ES274335A1 (en) | 1961-10-30 | 1962-01-29 | Preparation of derivatives of 1, 4-benzodioxan |
ES0274332A Expired ES274332A1 (en) | 1961-10-30 | 1962-01-29 | Preparation of derivatives of 1, 4-benzodioxan |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES0274332A Expired ES274332A1 (en) | 1961-10-30 | 1962-01-29 | Preparation of derivatives of 1, 4-benzodioxan |
Country Status (2)
Country | Link |
---|---|
US (1) | US3149108A (en) |
ES (2) | ES274335A1 (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4056540A (en) * | 1974-01-01 | 1977-11-01 | Bristol-Myers Company | 4-Phenyl-1,3-benzodioxans |
US4039676A (en) * | 1975-06-23 | 1977-08-02 | Ciba-Geigy Corporation | 2-piperidinoalkyl-1,4-benzodioxans |
US4129655A (en) * | 1976-04-26 | 1978-12-12 | Ciba-Geigy Corporation | Neuroleptic 2-piperidinoalkyl-1,4-benzodioxans |
-
1961
- 1961-10-30 US US148704A patent/US3149108A/en not_active Expired - Lifetime
-
1962
- 1962-01-29 ES ES0274335A patent/ES274335A1/en not_active Expired
- 1962-01-29 ES ES0274332A patent/ES274332A1/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
US3149108A (en) | 1964-09-15 |
ES274332A1 (en) | 1962-06-01 |
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