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ES274335A1 - Preparation of derivatives of 1, 4-benzodioxan - Google Patents

Preparation of derivatives of 1, 4-benzodioxan

Info

Publication number
ES274335A1
ES274335A1 ES0274335A ES274335A ES274335A1 ES 274335 A1 ES274335 A1 ES 274335A1 ES 0274335 A ES0274335 A ES 0274335A ES 274335 A ES274335 A ES 274335A ES 274335 A1 ES274335 A1 ES 274335A1
Authority
ES
Spain
Prior art keywords
general formula
amino group
group
nr1r2
inorganic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0274335A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
JR Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by JR Geigy AG filed Critical JR Geigy AG
Publication of ES274335A1 publication Critical patent/ES274335A1/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D319/00Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/101,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/141,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/161,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/201,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Process for the preparation of new 1,4-benzodioxane compounds of the general formula I ** (See formula) ** in which NR1R2 means the amino group or a mono- or bi-substituted aliphatic or heterocyclic amino group, R means hydrogen or a lower alkyl radical, Y means hydrogen, a halogen atom, a hydroxyl group, a lower alkyl group or a lower alkoxy group and n is 1,2,3,4 or 5, as well as its non-toxic salts with inorganic or organic acids, characterized in that a nitrile of the general formula II ** (See formula) ** in which R, Y and n have the meaning already expressed, is reduced catalytically or chemically to an amine of the general formula III ** (See formula) ** wherein R, Y and n have the meaning already expressed, and, if desired, the free amino group, -NH2, is converted in a manner already known per se to a substituted amino group, -NR1R2, and likewise, if desired, the compound obtained, of the general formula I, is converted into a salt with an inorganic or organic acid. (Machine-translation by Google Translate, not legally binding)
ES0274335A 1961-10-30 1962-01-29 Preparation of derivatives of 1, 4-benzodioxan Expired ES274335A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US148704A US3149108A (en) 1961-10-30 1961-10-30 Preparation of derivatives of 1, 4-benzodioxan

Publications (1)

Publication Number Publication Date
ES274335A1 true ES274335A1 (en) 1962-06-01

Family

ID=22526973

Family Applications (2)

Application Number Title Priority Date Filing Date
ES0274335A Expired ES274335A1 (en) 1961-10-30 1962-01-29 Preparation of derivatives of 1, 4-benzodioxan
ES0274332A Expired ES274332A1 (en) 1961-10-30 1962-01-29 Preparation of derivatives of 1, 4-benzodioxan

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES0274332A Expired ES274332A1 (en) 1961-10-30 1962-01-29 Preparation of derivatives of 1, 4-benzodioxan

Country Status (2)

Country Link
US (1) US3149108A (en)
ES (2) ES274335A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4056540A (en) * 1974-01-01 1977-11-01 Bristol-Myers Company 4-Phenyl-1,3-benzodioxans
US4039676A (en) * 1975-06-23 1977-08-02 Ciba-Geigy Corporation 2-piperidinoalkyl-1,4-benzodioxans
US4129655A (en) * 1976-04-26 1978-12-12 Ciba-Geigy Corporation Neuroleptic 2-piperidinoalkyl-1,4-benzodioxans

Also Published As

Publication number Publication date
US3149108A (en) 1964-09-15
ES274332A1 (en) 1962-06-01

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