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ES2571998T3 - Composiciones y usos médicos de derivados del ajoeno - Google Patents

Composiciones y usos médicos de derivados del ajoeno

Info

Publication number
ES2571998T3
ES2571998T3 ES11799621T ES11799621T ES2571998T3 ES 2571998 T3 ES2571998 T3 ES 2571998T3 ES 11799621 T ES11799621 T ES 11799621T ES 11799621 T ES11799621 T ES 11799621T ES 2571998 T3 ES2571998 T3 ES 2571998T3
Authority
ES
Spain
Prior art keywords
compositions
medical uses
ajoene derivatives
ajoene
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES11799621T
Other languages
English (en)
Inventor
Thomas Bjarnsholt
Niels Høiby
Peter Østrup Jensen
Richard Phipps
Meenakshi Sundaram Shanmugham
Maria Van Gennip
Louise Dahl Christensen
Tim Holm Jakobsen
David Tanner
Thomas Ostenfeld Larsen
Michael Givskov
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Danmarks Tekniske Universitet
Original Assignee
Danmarks Tekniske Universitet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Danmarks Tekniske Universitet filed Critical Danmarks Tekniske Universitet
Application granted granted Critical
Publication of ES2571998T3 publication Critical patent/ES2571998T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
    • A61K31/105—Persulfides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/22—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of hydropolysulfides or polysulfides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/06—Respiratory or anaesthetic masks
    • A61M16/0683—Holding devices therefor
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

(E,Z)-ajoeno de fórmula (1)**Fórmula** para usar en el tratamiento de infecciones bacterianas, donde la infección bacteriana es una infección por una bacteria formadora de biopelícula.
ES11799621T 2010-12-08 2011-12-07 Composiciones y usos médicos de derivados del ajoeno Active ES2571998T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US42092210P 2010-12-08 2010-12-08
EP10194154 2010-12-08
PCT/DK2011/050467 WO2012076016A1 (en) 2010-12-08 2011-12-07 Process for the manufacture of ajoene derivatives

Publications (1)

Publication Number Publication Date
ES2571998T3 true ES2571998T3 (es) 2016-05-27

Family

ID=43903893

Family Applications (1)

Application Number Title Priority Date Filing Date
ES11799621T Active ES2571998T3 (es) 2010-12-08 2011-12-07 Composiciones y usos médicos de derivados del ajoeno

Country Status (9)

Country Link
US (2) US20140303070A1 (es)
EP (2) EP3020397B1 (es)
JP (2) JP6088433B2 (es)
CN (1) CN103328441B (es)
AU (1) AU2016203651B2 (es)
CA (1) CA2820393A1 (es)
ES (1) ES2571998T3 (es)
HK (1) HK1223013A1 (es)
WO (1) WO2012076016A1 (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014001170A (ja) * 2012-06-19 2014-01-09 Nagoya Seiraku Kk 分泌型ＩｇＡ誘導剤、及びその分泌型ＩｇＡ誘導剤を含む飲食品
BR112016013881A2 (pt) * 2013-12-20 2017-08-08 Koninklijke Philips Nv Membro para interface com um paciente, e interface com um paciente para a liberação de gás para um usuário
GB201420902D0 (en) * 2014-11-25 2015-01-07 Neem Biotech Ltd A process for producing Ajoene
GB2533975A (en) * 2014-12-30 2016-07-13 Trio Healthcare Ltd Antibiofilm compositions
WO2017044044A1 (en) * 2015-09-08 2017-03-16 Nanyang Technological University Method of inhibiting quorum sensing in pseudomonas aeruginosa
CN106311734B (zh) * 2016-08-18 2019-06-25 浙江工商大学 用于土壤抗生素抗性基因污染消减的药剂及其制备和应用
CN106518739B (zh) * 2016-10-31 2018-12-04 中山大学 一种从黑大蒜中提取分离阿霍烯的方法
US11116813B2 (en) 2017-03-30 2021-09-14 Mootral Sa Antimicrobial garlic compositions
CN110234627B (zh) * 2017-04-11 2023-09-01 三井化学植保株式会社 吡啶酮化合物及以吡啶酮化合物作为有效成分的农园艺用杀菌剂
GB201818029D0 (en) * 2018-11-05 2018-12-19 Neem Biotech Ltd Organosulfur compounds
GB201901237D0 (en) * 2019-01-30 2019-03-20 Neem Biotech Ltd Disulphide compounds
CN111166732A (zh) * 2020-01-14 2020-05-19 广东省微生物研究所（广东省微生物分析检测中心） 二烯丙基二硫醚在制备抑制铜绿假单胞菌双组分系统药物中的应用
CA3168188A1 (en) * 2020-03-13 2021-09-16 Gerrit Jan STREEFLAND Compositions for disrupting biofilm formation and for treating biofilm-related disorders
WO2023038522A1 (en) * 2021-09-10 2023-03-16 AHV International B.V. Compositions and methods for treating biofilm disorders and infection

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4665088A (en) 1984-11-14 1987-05-12 The Research Foundation Of State University Of New York (E-Z)-4,5,9-trithiadodeca-1,6,11-triene 9-oxides
US4643994A (en) 1984-12-17 1987-02-17 The Research Foundation Of State University Of New York Novel organic trithio oxides and method for the preparation thereof
CA2306812A1 (en) * 1997-10-23 1999-04-29 Pharmaprint, Inc. Pharmaceutical grade garlic
GB0120887D0 (en) * 2001-08-29 2001-10-17 Sahajanand Biotech Private Ltd Local drug delivery system in coronary stents
GB0122793D0 (en) * 2001-09-21 2001-11-14 Stone Island Holdings Ltd Allicin
WO2005089571A1 (es) * 2004-03-03 2005-09-29 Mousala, S., L. Utilización de extractos y compuestos de plantas del género allium como conservantes en las industrias alimentaria y agroalimentaria
GB0903869D0 (en) * 2009-03-05 2009-04-22 Neem Biotech Ltd Process for the preparation of ajoene

Also Published As

Publication number Publication date
CN103328441A (zh) 2013-09-25
CA2820393A1 (en) 2012-06-14
JP2017061525A (ja) 2017-03-30
EP3020397B1 (en) 2019-04-17
CN103328441B (zh) 2016-08-31
AU2016203651A1 (en) 2016-06-16
EP3020397A2 (en) 2016-05-18
US20140303070A1 (en) 2014-10-09
AU2011341155A1 (en) 2013-06-27
JP6088433B2 (ja) 2017-03-01
US20180360773A1 (en) 2018-12-20
EP2649047B1 (en) 2016-02-24
AU2016203651B2 (en) 2017-06-01
US10603289B2 (en) 2020-03-31
EP2649047A1 (en) 2013-10-16
JP6253749B2 (ja) 2017-12-27
HK1223013A1 (zh) 2017-07-21
EP3020397A3 (en) 2016-08-17
WO2012076016A1 (en) 2012-06-14
JP2014508719A (ja) 2014-04-10

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