[go: up one dir, main page]

ES2525330T3 - Uso de sulfato de condroitina para reducir la unión no específica en inmunoensayos de troponina I - Google Patents

Uso de sulfato de condroitina para reducir la unión no específica en inmunoensayos de troponina I Download PDF

Info

Publication number
ES2525330T3
ES2525330T3 ES08252839.9T ES08252839T ES2525330T3 ES 2525330 T3 ES2525330 T3 ES 2525330T3 ES 08252839 T ES08252839 T ES 08252839T ES 2525330 T3 ES2525330 T3 ES 2525330T3
Authority
ES
Spain
Prior art keywords
troponin
analyte
chondroitin sulfate
specific binding
reduce non
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES08252839.9T
Other languages
English (en)
Inventor
Banumathi Sankaran
Sheryl S. Sullivan
Darrell C. Haynes
Philip C. Hosimer
Graham Yearwood
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ortho Clinical Diagnostics Inc
Original Assignee
Ortho Clinical Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39967577&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2525330(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ortho Clinical Diagnostics Inc filed Critical Ortho Clinical Diagnostics Inc
Application granted granted Critical
Publication of ES2525330T3 publication Critical patent/ES2525330T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5306—Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

Un reactivo de inmunoensayo que comprende: un agente de unión al analito en un diluyente; y sulfato de condroitina en una cantidad suficiente para reducir la unión no específica en un ensayo de una muestra para el analito, en el que el analito es troponina I, en el que el agente de unión al analito es un anticuerpo para el analito o un receptor para el analito.

Description

imagen1
imagen2
imagen3
imagen4
imagen5
imagen6
imagen7

Claims (1)

  1. imagen1
ES08252839.9T 2007-08-28 2008-08-28 Uso de sulfato de condroitina para reducir la unión no específica en inmunoensayos de troponina I Active ES2525330T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/846,390 US8617820B2 (en) 2007-08-28 2007-08-28 Use of glycosaminoglycans to reduce non-specific binding in immunoassays
US846390 2007-08-28

Publications (1)

Publication Number Publication Date
ES2525330T3 true ES2525330T3 (es) 2014-12-22

Family

ID=39967577

Family Applications (1)

Application Number Title Priority Date Filing Date
ES08252839.9T Active ES2525330T3 (es) 2007-08-28 2008-08-28 Uso de sulfato de condroitina para reducir la unión no específica en inmunoensayos de troponina I

Country Status (13)

Country Link
US (1) US8617820B2 (es)
EP (1) EP2031392B1 (es)
JP (1) JP5274934B2 (es)
KR (1) KR101557034B1 (es)
CN (1) CN101377488B (es)
AR (1) AR068043A1 (es)
AU (1) AU2008207454B2 (es)
BR (1) BRPI0803650A2 (es)
CA (1) CA2639196C (es)
CL (1) CL2008002525A1 (es)
ES (1) ES2525330T3 (es)
HK (1) HK1130089A1 (es)
RU (1) RU2490648C2 (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2380026B1 (en) * 2008-12-22 2016-03-23 Koninklijke Philips N.V. Assay for troponin i using magnetic labels
CN103975241B (zh) * 2011-08-03 2016-01-20 奎德尔公司 用于提高a型链球菌免疫测定法的特异性的n-乙酰基-d-葡糖胺
EP2843412B1 (en) 2012-04-27 2018-01-03 Konica Minolta, Inc. Antigen detection method which uses lectin and comprises enzyme treatment step
WO2014103553A1 (ja) * 2012-12-28 2014-07-03 コニカミノルタ株式会社 夾雑物の影響を低減する免疫測定法
EP3088896B1 (en) 2013-12-27 2019-11-06 Konica Minolta, Inc. Method for analyzing information for diagnosis and kit therefor
JP6323463B2 (ja) 2013-12-27 2018-05-16 コニカミノルタ株式会社 診断用情報の分析方法およびそのためのキット
JP6520940B2 (ja) 2014-06-20 2019-05-29 コニカミノルタ株式会社 標識化レクチンを用いるサンドイッチ型アッセイおよびそのためのキット
JP6651794B2 (ja) * 2015-11-05 2020-02-19 富士レビオ株式会社 心筋トロポニンｉ測定試薬及び方法
KR102228440B1 (ko) * 2016-04-13 2021-03-15 가부시키가이샤 엘에스아이 메디엔스 황산화 다당류를 이용한 면역학적 측정법
WO2018138264A2 (en) 2017-01-27 2018-08-02 Roche Diagnostics Gmbh Methods for modulating signal intensity in interaction assays
JP7420557B2 (ja) * 2017-03-07 2024-01-23 オルト－クリニカル ダイアグノスティックス インコーポレイテッド 分析物を検出するための方法
CN110446927A (zh) * 2017-03-22 2019-11-12 富士胶片和光纯药株式会社 具有糖链的物质与凝集素的复合物形成方法
EP4314828A1 (en) 2021-04-01 2024-02-07 Becton, Dickinson and Company Methods for enhancing specificity and sensitivity of group a streptococcus immunoassay
CN113671195A (zh) * 2021-09-13 2021-11-19 迈克生物股份有限公司 抗双链dna抗体检测试剂盒及其应用

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02238361A (ja) 1989-03-10 1990-09-20 Sekisui Chem Co Ltd 免疫反応測定法および免疫反応測定用試薬
DE3922873A1 (de) * 1989-04-25 1990-10-31 Boehringer Mannheim Gmbh Spezifische antikoerper gegen troponin t, ihre herstellung und verwendung in einem reagenz zur bestimmung von hermuskelnekrosen
US5529985A (en) * 1990-04-23 1996-06-25 Akzo Nobel Nv Sulfated glycosaminoglycanoid derivatives of the dermatan sulfate and chondroitin sulfate type
ES2136090T3 (es) * 1991-05-30 1999-11-16 Abbott Lab Reactivos que contienen un inhibidor de fijacion no especifico para analisis de fijacion con captura de iones.
FR2718849B1 (fr) * 1994-04-14 1996-06-14 Pasteur Sanofi Diagnostics Procédé d'immunodosage de l'antithrombine III activée par un glycosaminoglycane, anticorps monoclonaux correspondants et leur procédé d'obtention.
JP2649016B2 (ja) 1994-07-15 1997-09-03 三洋化成工業株式会社 免疫反応干渉作用の除去方法
AU3483395A (en) 1994-09-28 1996-04-19 Spectral Diagnostics Inc. A monoclonal antibody to human cardiac troponin i
US5639626A (en) * 1994-11-15 1997-06-17 Chiron Diagnostics Corporation Reagents for specific binding assays
US6627404B1 (en) * 1995-04-18 2003-09-30 Biosite, Inc. Methods for improving the recovery of troponin I and T in membranes, filters and vessels
US6991907B1 (en) * 1995-04-18 2006-01-31 Biosite, Inc. Methods for the assay of troponin I and T and complexes of troponin I and T and selection of antibodies for use in immunoassays
US5616460A (en) * 1995-06-07 1997-04-01 Abbott Laboratories Buffer composition for reagents for immunoassay
RU2122736C1 (ru) * 1996-01-31 1998-11-27 Научно-технический центр "Лекбиотех" Набор для выявления сенсибилизирующих аллергенов методом твердофазного иммуноферментного анализа
US5922690A (en) * 1996-04-25 1999-07-13 Van Gorp; Cornelius L. Dermatan disulfate, an inhibitor of thrombin generation and activation
JP2000065837A (ja) * 1998-08-24 2000-03-03 Seikagaku Kogyo Co Ltd グリコサミノグリカン又はグリコサミノグリカン結合性分子の測定方法及びその測定用キット
WO2000029029A1 (en) * 1998-11-12 2000-05-25 Novolytics Inc. Compositions and methods for producing vascular occlusion
JP4454885B2 (ja) 2001-05-21 2010-04-21 アルフレッサファーマ株式会社 免疫測定方法およびそのための試薬
CA2515850A1 (en) * 2003-04-14 2004-10-28 Caliper Life Sciences, Inc. Reduction of migration shift assay interference
US7172906B2 (en) * 2004-11-16 2007-02-06 Dade Behring Inc. Reduction of non-specific binding in assays
EP1960783B1 (en) * 2005-11-17 2015-05-27 Siemens Healthcare Diagnostics Inc. Reduction of non-specific binding in assays

Also Published As

Publication number Publication date
CN101377488A (zh) 2009-03-04
HK1130089A1 (en) 2009-12-18
EP2031392A1 (en) 2009-03-04
AR068043A1 (es) 2009-10-28
US8617820B2 (en) 2013-12-31
JP2009053195A (ja) 2009-03-12
CA2639196A1 (en) 2009-02-28
AU2008207454A1 (en) 2009-03-19
KR20090023223A (ko) 2009-03-04
RU2490648C2 (ru) 2013-08-20
JP5274934B2 (ja) 2013-08-28
CA2639196C (en) 2016-07-19
EP2031392B1 (en) 2014-09-24
RU2008135060A (ru) 2010-03-10
BRPI0803650A2 (pt) 2009-05-05
CN101377488B (zh) 2015-04-01
AU2008207454B2 (en) 2015-03-26
US20090061455A1 (en) 2009-03-05
KR101557034B1 (ko) 2015-10-02
CL2008002525A1 (es) 2009-01-16

Similar Documents

Publication Publication Date Title
ES2525330T3 (es) Uso de sulfato de condroitina para reducir la unión no específica en inmunoensayos de troponina I
ES2487846T3 (es) Anticuerpos anti-hepcindina y métodos de uso
ES2548133T3 (es) Método de detección de niveles muy bajos de analito en una muestra fluida de película delgada contenida en una cámara de pequeño espesor
ES2507520T3 (es) Aislamiento y/o identificación de células madre con potencial de diferenciación adipocitario, condrocitario y pancreático
ES2527961T3 (es) Anticuerpos monoclonales humanos para CD70
BR0111731A (pt) Ensaio de combinação de anticorpo/antìgeno do hcv
HK1097320A1 (en) Detection of methamphetamine group drugs
BR0316384A (pt) Imunoensaio não competitivo para analitos pequenos
BRPI0814343A2 (pt) Materiais e métodos para a seleção da sexagem do esperma
ES2484142T3 (es) Diagnóstico molecular y clasificación del melanoma maligno
WO2007035633A3 (en) Screening assays and methods
CO6280567A2 (es) Establecimiento de un anticuerpo monoclonal para detector de proteinas pag en la circulacion
AR053948A1 (es) Deteccion de un antigeno diana independientemente de la presencia o ausencia de un anticuerpo terapeutico correspondiente
CL2011002509A1 (es) Cartucho para la verificacion y el analisis cuantitativo de analito en un liquido de muestra que incorpora una camara de reactivos, una camara de deteccion; procedimiento para analisis cuantitativo de analito; y uso del cartucho.
WO2005103698A3 (en) Methods and antibodies for nitrofuran detection
WO2007024735A3 (en) Method and antibodies for detecting nitrofuran
ATE485514T1 (de) Immunoassay mit mehreren analyten
DE602006014120D1 (de) Kolloidale metallkonjugate
ATE474857T1 (de) Antikörper gegen ein epitop auf agr2, assays und hybridome
EP2674757A3 (en) Agglutination assay
WO2007076013A3 (en) Homocysteine immunoassay
ATE405837T1 (de) Festphase immunochromatographische testverfahren
ES2535426T3 (es) Anticuerpos anti-TNFα y métodos de uso
WO2010053772A3 (en) Disease-associated antigens and methods of use thereof
WO2009016718A1 (ja) 診断薬及びそれを用いた診断方法