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ES2395083T8 - Ácidos bifenilcarboxílicos y sus derivados - Google Patents

Ácidos bifenilcarboxílicos y sus derivados Download PDF

Info

Publication number
ES2395083T8
ES2395083T8 ES08839835.9T ES08839835T ES2395083T8 ES 2395083 T8 ES2395083 T8 ES 2395083T8 ES 08839835 T ES08839835 T ES 08839835T ES 2395083 T8 ES2395083 T8 ES 2395083T8
Authority
ES
Spain
Prior art keywords
derivatives
biphenylcarboxylic acids
biphenylcarboxylic
acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES08839835.9T
Other languages
English (en)
Other versions
ES2395083T3 (es
Inventor
Chih Yung Ho
Umar S M Maharoof
Jeremy Major
John Harrison
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceutica NV
Cellzome Ltd
Original Assignee
Janssen Pharmaceutica NV
Cellzome Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica NV, Cellzome Ltd filed Critical Janssen Pharmaceutica NV
Application granted granted Critical
Publication of ES2395083T3 publication Critical patent/ES2395083T3/es
Publication of ES2395083T8 publication Critical patent/ES2395083T8/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/58Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C07C59/68Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
ES08839835T 2007-10-17 2008-09-26 Ácidos bifenilcarboxílicos y sus derivados Active ES2395083T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US98058707P 2007-10-17 2007-10-17
US980587P 2007-10-17
PCT/US2008/077779 WO2009051948A1 (en) 2007-10-17 2008-09-26 Biphenyl carboxylic acids and derivatives thereof

Publications (2)

Publication Number Publication Date
ES2395083T3 ES2395083T3 (es) 2013-02-08
ES2395083T8 true ES2395083T8 (es) 2014-11-17

Family

ID=40345060

Family Applications (1)

Application Number Title Priority Date Filing Date
ES08839835T Active ES2395083T3 (es) 2007-10-17 2008-09-26 Ácidos bifenilcarboxílicos y sus derivados

Country Status (18)

Country Link
US (1) US7897643B2 (es)
EP (1) EP2215044B8 (es)
JP (1) JP5404634B2 (es)
KR (1) KR101579744B1 (es)
CN (1) CN101861297B (es)
AU (1) AU2008312771B2 (es)
BR (1) BRPI0817424A2 (es)
CA (1) CA2702832A1 (es)
CO (1) CO6270313A2 (es)
CR (1) CR11432A (es)
DK (1) DK2215044T3 (es)
EA (1) EA017616B1 (es)
ES (1) ES2395083T3 (es)
IL (1) IL205047A (es)
MX (1) MX2010004261A (es)
NI (1) NI201000058A (es)
WO (1) WO2009051948A1 (es)
ZA (1) ZA201003432B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101903347B (zh) * 2007-10-19 2013-03-27 詹森药业有限公司 带哌啶基和哌嗪基的γ-分泌酶调节剂
CA2703636A1 (en) * 2007-10-19 2009-04-23 Janssen Pharmaceutica N.V. Amine linked modulators of .gamma.-secretase
CN101896452B (zh) * 2007-10-19 2013-07-31 詹森药业有限公司 连接有碳的γ-分泌酶调节剂

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5877399A (en) 1994-01-27 1999-03-02 Johns Hopkins University Transgenic mice expressing APP-Swedish mutation develop progressive neurologic disease
AU2001257022B2 (en) 2000-04-13 2005-02-03 Mayo Foundation For Medical Education And Research Abeta 42 lowering agents
DE10131899A1 (de) 2001-07-04 2003-02-27 Boehringer Ingelheim Pharma In vitro-Screening-Assay für gamma-Secretase
US20080313061A1 (en) 2004-06-30 2008-12-18 Paysetter Pte Ltd System and Method for Facilitating Transfer of Physical Money and/or Credit
DE102004033876B4 (de) 2004-07-13 2009-01-15 Christoph Kaesbohrer Dreidimensionales Struktursystem
EP1650183A1 (en) * 2004-10-21 2006-04-26 Cellzome Ag (Benzyloxy-biphenyl) acetic acids and derivatives thereof and their use in therapy

Also Published As

Publication number Publication date
EP2215044B8 (en) 2012-10-03
CN101861297A (zh) 2010-10-13
WO2009051948A1 (en) 2009-04-23
MX2010004261A (es) 2010-04-30
CN101861297B (zh) 2014-04-23
NI201000058A (es) 2010-09-13
US20090105344A1 (en) 2009-04-23
ZA201003432B (en) 2012-07-25
BRPI0817424A2 (pt) 2015-06-16
JP2011500691A (ja) 2011-01-06
CR11432A (es) 2010-10-14
US7897643B2 (en) 2011-03-01
CA2702832A1 (en) 2009-04-23
DK2215044T3 (da) 2012-11-26
IL205047A0 (en) 2010-11-30
KR101579744B1 (ko) 2015-12-23
JP5404634B2 (ja) 2014-02-05
CO6270313A2 (es) 2011-04-20
KR20100090264A (ko) 2010-08-13
EP2215044A1 (en) 2010-08-11
AU2008312771A1 (en) 2009-04-23
AU2008312771B2 (en) 2012-11-01
ES2395083T3 (es) 2013-02-08
EA017616B1 (ru) 2013-01-30
EP2215044B1 (en) 2012-08-29
EA201070478A1 (ru) 2010-10-29
IL205047A (en) 2014-09-30

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