ES2175171T3 - Procedimiento para la fabricacion de un polimero cristalino de hidrocloruro de terazosina. - Google Patents
Procedimiento para la fabricacion de un polimero cristalino de hidrocloruro de terazosina.Info
- Publication number
- ES2175171T3 ES2175171T3 ES96943936T ES96943936T ES2175171T3 ES 2175171 T3 ES2175171 T3 ES 2175171T3 ES 96943936 T ES96943936 T ES 96943936T ES 96943936 T ES96943936 T ES 96943936T ES 2175171 T3 ES2175171 T3 ES 2175171T3
- Authority
- ES
- Spain
- Prior art keywords
- hydrocloride
- terazosine
- polymer
- procedure
- manufacture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Silicon Polymers (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
UN POLIMORFO CRISTALINO DE MONOCLORHIDRATO DE TERAZOSINA SE OBTIENE SUSPENDIENDO Y TRATANDO UN ADUCTO CRISTALINO DE CLORHIDRATO DE TERAZOSINA Y METANOL EN UN DISOLVENTE POLAR, EL CUAL ES UN ALCOHOL CON DOS A SEIS ATOMOS DE CARBONO O UNA CETONA CON DOS A SEIS ATOMOS DE CARBONO O UNA MEZCLA DE LOS MISMOS. EL POLIMORFO CRISTALINO ASI OBTENIDO SE CARACTERIZA POR LA BAJA HIGROSCOPICIDAD Y REDUCIDA CAPACIDAD DE RETENCION DEL DISOLVENTE RESIDUAL.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19546573A DE19546573A1 (de) | 1995-12-13 | 1995-12-13 | Kristallines Polymorph von Terazosin-Hydrochlorid, sowie Verfahren zu seiner Herstellung |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2175171T3 true ES2175171T3 (es) | 2002-11-16 |
Family
ID=7780037
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES96943936T Expired - Lifetime ES2175171T3 (es) | 1995-12-13 | 1996-12-12 | Procedimiento para la fabricacion de un polimero cristalino de hidrocloruro de terazosina. |
Country Status (8)
Country | Link |
---|---|
US (1) | US5959108A (es) |
EP (1) | EP0866792B1 (es) |
AT (1) | ATE216383T1 (es) |
DE (2) | DE19546573A1 (es) |
ES (1) | ES2175171T3 (es) |
PT (1) | PT866792E (es) |
WO (1) | WO1997021705A1 (es) |
ZA (1) | ZA9610406B (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5952003A (en) * | 1996-08-01 | 1999-09-14 | Novartis Corporation | Terazosin capsules |
IT1286790B1 (it) * | 1996-11-29 | 1998-07-17 | Alfa Chem Ital | Processo per la produzione della forma i del terazosin monocloridrato anidro |
IT1286789B1 (it) * | 1996-11-29 | 1998-07-17 | Alfa Chem Ital | Processo per la produzione della forma i del terazosin monocloridato anidro |
AU2002246688A1 (en) * | 2000-12-18 | 2002-07-30 | Altus Biologics Inc. | Methods for preparing purified daptomycin |
US20060014674A1 (en) | 2000-12-18 | 2006-01-19 | Dennis Keith | Methods for preparing purified lipopeptides |
DE10223913A1 (de) * | 2002-05-29 | 2003-12-11 | Bayer Cropscience Ag | Verfahren zur Herstellung spezifischer Kristallmodifikationen polymorpher Substanzen |
US20060264442A1 (en) * | 2005-05-18 | 2006-11-23 | Allergan, Inc. | Methods for the treatment of ocular and neurodegenerative conditions in a mammal |
WO2017106958A1 (en) | 2015-12-21 | 2017-06-29 | The University Of British Columbia | Highly parallel assays for simultaneous identification of antibody sequences and binding partners |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4026894A (en) * | 1975-10-14 | 1977-05-31 | Abbott Laboratories | Antihypertensive agents |
US5212176A (en) * | 1990-06-29 | 1993-05-18 | Abbott Laboratories | R(+)-terazosin |
JP2652272B2 (ja) * | 1990-12-31 | 1997-09-10 | 住化ファインケム株式会社 | 1−(4−アミノ−6,7−ジメトキシ−2−キナゾリニル)−4−(2−テトラヒドロフロイル)ピペラジン塩酸塩の新規な結晶体および該結晶体の製造方法 |
US5294615A (en) * | 1993-04-29 | 1994-03-15 | Abbott Laboratories | Terazosin polymorph and pharmaceutical composition |
US5412095A (en) * | 1993-04-29 | 1995-05-02 | Abbott Laboratories | Terazosin monohydrochloride and processes and intermediate for its production |
US5504207A (en) * | 1994-10-18 | 1996-04-02 | Abbott Laboratories | Process and intermediate for the preparation of terazosin hydrochloride dihydrate |
US5587377A (en) * | 1995-10-24 | 1996-12-24 | Invamed, Inc. | Terazosin crystalline polymorph and pharmaceutical compositions thereof |
-
1995
- 1995-12-13 DE DE19546573A patent/DE19546573A1/de not_active Withdrawn
-
1996
- 1996-12-11 ZA ZA9610406A patent/ZA9610406B/xx unknown
- 1996-12-12 PT PT96943936T patent/PT866792E/pt unknown
- 1996-12-12 EP EP96943936A patent/EP0866792B1/de not_active Expired - Lifetime
- 1996-12-12 ES ES96943936T patent/ES2175171T3/es not_active Expired - Lifetime
- 1996-12-12 WO PCT/EP1996/005570 patent/WO1997021705A1/de active IP Right Grant
- 1996-12-12 DE DE59609108T patent/DE59609108D1/de not_active Expired - Fee Related
- 1996-12-12 AT AT96943936T patent/ATE216383T1/de not_active IP Right Cessation
-
1998
- 1998-06-10 US US09/095,483 patent/US5959108A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DE19546573A1 (de) | 1997-06-19 |
EP0866792A1 (de) | 1998-09-30 |
ZA9610406B (en) | 1998-06-11 |
US5959108A (en) | 1999-09-28 |
ATE216383T1 (de) | 2002-05-15 |
DE59609108D1 (de) | 2002-05-23 |
EP0866792B1 (de) | 2002-04-17 |
WO1997021705A1 (de) | 1997-06-19 |
PT866792E (pt) | 2002-09-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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