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ES2173203T3 - Composicion que comprende una formulacion que actua contra las enfermedades sexualmente transmisibles y su utilizacion. - Google Patents

Composicion que comprende una formulacion que actua contra las enfermedades sexualmente transmisibles y su utilizacion.

Info

Publication number
ES2173203T3
ES2173203T3 ES95937526T ES95937526T ES2173203T3 ES 2173203 T3 ES2173203 T3 ES 2173203T3 ES 95937526 T ES95937526 T ES 95937526T ES 95937526 T ES95937526 T ES 95937526T ES 2173203 T3 ES2173203 T3 ES 2173203T3
Authority
ES
Spain
Prior art keywords
ets
composition
formulation
infectant
allows
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95937526T
Other languages
English (en)
Inventor
William Joseph Bologna
Howard Leslie Levine
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Columbia Laboratories Bermuda Ltd
Original Assignee
Columbia Laboratories Bermuda Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Columbia Laboratories Bermuda Ltd filed Critical Columbia Laboratories Bermuda Ltd
Application granted granted Critical
Publication of ES2173203T3 publication Critical patent/ES2173203T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/14—Topical contraceptives and spermacides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Gynecology & Obstetrics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

LA PRESENTE INVENCION PROPORCIONA UNA COMPOSICION Y USO DE UNA COMPOSICION QUE INCLUYE UNA FORMULACION POLIMERICA DE ACIDO POLICARBOXILICO DE ENLACE CRUZADO BIOADHESIVO QUE PERMITE EL USO DE CANTIDADES RELATIVAMENTE BAJAS DE AGENTES ANTI-STD COMO N-9, PARA SER USADOS EN LA PREVENCION DE LA INFECCION POR ETS SIN PROVOCAR LA IRRITACION DEL TEJIDO GENITAL QUE A MENUDO ACOMPAÑA A LAS DOSIS MAYORES DE ANTI-ETS. EL POLIMERO BIOADHESIVO MANTIENE UN CONTACTO MAYOR ENTRE EL AGENTE ANTI ETS Y EL INFECTANTE DURANTE UN PERIODO MUCHO MAYOR DE TIEMPO, PERMITIENDO CON UNA CONCENTRACION INFERIOR ACTUAR POR MAS TIEMPO SOBRE EL INFECTANTE, CUANDO SE COMPARA CON LAS APLICACIONES COMERCIALES NORMALMENTE DISPONIBLES QUE CONTIENEN N-9. TAL SUMINISTRO DA UNA SEGURIDAD Y PERMITE UNA DISMINUCION NO IRRITANTE EN EL RIESGO DE SUFRIR UNA INFECCION ETS, INCLUYENDO HIV.
ES95937526T 1994-10-07 1995-10-06 Composicion que comprende una formulacion que actua contra las enfermedades sexualmente transmisibles y su utilizacion. Expired - Lifetime ES2173203T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/319,495 US5667492A (en) 1994-10-07 1994-10-07 Use and composition of an anti-sexually transmitted diseases formulation

Publications (1)

Publication Number Publication Date
ES2173203T3 true ES2173203T3 (es) 2002-10-16

Family

ID=23242477

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95937526T Expired - Lifetime ES2173203T3 (es) 1994-10-07 1995-10-06 Composicion que comprende una formulacion que actua contra las enfermedades sexualmente transmisibles y su utilizacion.

Country Status (24)

Country Link
US (2) US5667492A (es)
EP (1) EP0784466B1 (es)
JP (1) JPH10507178A (es)
KR (1) KR970705976A (es)
AT (1) ATE213623T1 (es)
AU (1) AU704836B2 (es)
BR (1) BR9509280A (es)
CA (1) CA2201872A1 (es)
CO (1) CO4480018A1 (es)
DE (1) DE69525634T2 (es)
DK (1) DK0784466T3 (es)
ES (1) ES2173203T3 (es)
FI (1) FI971440A0 (es)
HU (1) HUT77527A (es)
IL (1) IL115495A0 (es)
MA (1) MA23687A1 (es)
MX (1) MX9504245A (es)
NO (1) NO971491L (es)
NZ (1) NZ295947A (es)
PE (1) PE46996A1 (es)
PT (1) PT784466E (es)
RU (1) RU2157184C2 (es)
WO (1) WO1996010989A1 (es)
ZA (1) ZA958434B (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005007194A1 (es) * 2003-07-16 2005-01-27 Italfarmaco, S.A. Formulaciones mucoadhesivas semisólidas

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6596777B1 (en) 1997-05-29 2003-07-22 Mcneil-Ppc, Inc. Moisture containing compositions that are spreadable onto and adherable to biomembranes
US6440980B1 (en) * 1996-09-17 2002-08-27 Avanir Pharmaceuticals Synergistic inhibition of viral replication by long-chain hydrocarbons and nucleoside analogs
US5942243A (en) * 1996-11-12 1999-08-24 Polytherapeutics, Inc. Mucoadhesive compositions for administration of biologically active agents to animal tissue
AU7484198A (en) * 1997-05-12 1998-12-08 Sage Pharmaceuticals, Inc. Topical spray for burn treatment and anti-infection
EP1356806A1 (en) * 1997-09-12 2003-10-29 Columbia Laboratories (Bermuda) Limited A pharmaceutical composition for treating dysmenorrhea and premature labor
US20040234606A1 (en) * 1997-09-12 2004-11-25 Levine Howard L. Localized vaginal delivery without detrimental blood levels
DE69819748T2 (de) * 1997-09-12 2004-09-30 Columbia Laboratories (Bermuda) Ltd. Arzneimittel zur behandlung von dysmenorrhöe und verfrühten wehen
US8765177B2 (en) * 1997-09-12 2014-07-01 Columbia Laboratories, Inc. Bioadhesive progressive hydration tablets
DE69910210T2 (de) 1998-06-19 2004-06-17 Oxibio, Inc., Portland Implantierbare medizinische vorrichtung mit antiinfektiösen und kontrazeptiven eigenschaften
AU4489399A (en) * 1998-06-23 2000-01-10 Notax Holding Gesellschaft M.B.H. Use of nonoxynol-9 as lubricant and method for its production
US6159491A (en) * 1999-02-12 2000-12-12 Biovector Technologies, Inc. Prolonged release bioadhesive vaginal gel dosage form
US6818672B1 (en) 1999-10-05 2004-11-16 Columbia Laboratories, Inc. Treating endometriosis or infertility, or improving fertility
US6479045B2 (en) 1999-12-22 2002-11-12 Columbia Laboratories, Inc. Vaginal pH buffering for preventing miscarriage and premature labor, by treating or preventing bacterial vaginosis
CN100488517C (zh) * 2000-03-07 2009-05-20 拉什-长老会-圣路加医学中心 捕获和灭活病原性微生物和精子的组合物及其制药用途
US7544348B2 (en) * 2001-02-15 2009-06-09 Access Pharmaceuticals, Inc. Liquid formulations for the prevention and treatment of mucosal diseases and disorders
PT1997478E (pt) * 2001-02-15 2013-12-10 Access Pharma Inc Formulações líquidas para a prevenção e para o tratamento de doenças e distúrbios das mucosas
US20060073174A1 (en) * 2001-08-16 2006-04-06 Access Pharmaceuticals, Inc. Adherent and erodible film to treat a moist surface of a body tissue
US6585997B2 (en) 2001-08-16 2003-07-01 Access Pharmaceuticals, Inc. Mucoadhesive erodible drug delivery device for controlled administration of pharmaceuticals and other active compounds
CN1633306A (zh) * 2001-10-16 2005-06-29 阿文尼尔药品公司 正－二十二烷醇的病毒抑制
US20080182841A1 (en) * 2001-10-29 2008-07-31 Levine Howard L Vaginally administered anti-dysrhythmic agents for treating pelvic pain
US7709026B2 (en) * 2001-10-29 2010-05-04 Columbia Laboratories, Inc. Low concentration of peroxide for treating or preventing vaginal infections
US20030114394A1 (en) * 2001-10-29 2003-06-19 Levine Howard L. Vaginally administered anti-dysrhythmic agents for treating pelvic pain
CN101327326A (zh) * 2001-10-29 2008-12-24 哥伦比亚实验室(百慕大群岛)有限公司 阴道给药治疗骨盆痛和不孕症的抗节律障碍剂
US8425892B2 (en) 2001-10-29 2013-04-23 Columbia Laboratories, Inc. Extended, controlled-release pharmaceutical compositions using charged polymers
KR20110132482A (ko) * 2003-02-07 2011-12-07 얀센 파마슈티카 엔.브이. Ｈｉｖ 감염 예방용 피리미딘 유도체
ITMI20031640A1 (it) 2003-08-08 2005-02-09 Mipharm S P A Base per gel bioadesivi.
US12011423B2 (en) 2007-11-06 2024-06-18 Foraviset Ltd. S-alkylisothiouronium derivatives for treating uterine hypercontractility disorders
ES2344673B1 (es) 2008-08-07 2011-05-03 Italfarmaco, S.A. Uso de estriol en la preparacion de una formulacion farmaceutica parael tratamiento de atrofia vaginal en mujeres con riesgo de potologiatumoral.
ES2344675B1 (es) 2008-12-19 2011-04-28 Italfarmaco, S.A. Uso de estriol en la preparacion de una formulacion farrmaceutica para el tratamiento de atrofia vaginal en mujeres con riesgo de patologiacardiovascular.
EP2861215A4 (en) 2012-06-13 2015-04-22 Evofem Inc COMPOSITIONS AND METHODS FOR INCREASING THE EFFECTIVENESS OF RECIPROCAL MICROBICIDES
AU2014368971B2 (en) 2013-12-19 2020-02-06 Evofem, Inc. Compositions and methods for inhibiting inflammation and diseases using an alginic acid-based antimicrobial compound
EP3169324B1 (en) * 2014-07-14 2019-05-08 Orion Biotechnology Canada Ltd. Microbicidal composition comprising an octoxynol and a quinolizidine alkaloid compound or a source thereof
EP3522879A4 (en) 2016-10-04 2020-06-03 Evofem, Inc. Method of treatment and prevention of bacterial vaginosis

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL265428A (es) * 1960-06-06
US4286593A (en) * 1980-05-05 1981-09-01 Place Virgil A Vaginal contraceptive shield
EP0305551A3 (en) * 1981-10-13 1990-01-10 Exovir, Inc. Pharmaceutical compositions for topical application
JPH0830004B2 (ja) * 1983-11-14 1996-03-27 コロンビア ラボラトリーズ インコーポレイテッド 生物接着性組成物およびそれにより治療する方法
US4983393A (en) * 1987-07-21 1991-01-08 Maximed Corporation Intra-vaginal device and method for sustained drug release
NO178843C (no) * 1988-07-11 1996-06-19 Sspl Sa Safe Sex Prod Licens Fremgangsmåte for fremstilling av et farmasöytisk preparat for å forhindre seksuelt overförbare sykdommer
US5000749A (en) * 1988-10-13 1991-03-19 Leveen Harry H Iodine contraceptive sponge
ATE112157T1 (de) * 1989-10-31 1994-10-15 Columbia Lab Inc Verfahren zur feuchthaltung von gewebe und mittel dazu.
DE69033199T2 (de) * 1989-10-31 1999-10-28 Columbia Lab Bermuda Ltd Mittel zur feuchthaltung von gewebe und verfahren
DK0431719T3 (da) * 1989-10-31 1995-02-27 Columbia Lab Inc Vaginalt vævsbefugtende præparat
US5380523A (en) * 1993-08-17 1995-01-10 University Of Kentucky Research Foundation High energy coprecipitate of nonoxynol oligomer, PVP and iodine having contraceptive and potent anti-HIV properties

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005007194A1 (es) * 2003-07-16 2005-01-27 Italfarmaco, S.A. Formulaciones mucoadhesivas semisólidas
ES2237298A1 (es) * 2003-07-16 2005-07-16 Italfarmaco, S.A. Formulaciones mucoadhesivas semisolidas.
US8663688B2 (en) 2003-07-16 2014-03-04 Itf Research Pharma, S.L.U. Semi-solid mucoadhesive formulations

Also Published As

Publication number Publication date
NZ295947A (en) 1999-02-25
AU704836B2 (en) 1999-05-06
EP0784466B1 (en) 2002-02-27
ZA958434B (en) 1996-05-08
BR9509280A (pt) 1997-11-18
HUT77527A (hu) 1998-05-28
RU2157184C2 (ru) 2000-10-10
MX9504245A (es) 1997-01-31
NO971491L (no) 1997-06-09
DE69525634D1 (de) 2002-04-04
PE46996A1 (es) 1996-11-23
ATE213623T1 (de) 2002-03-15
EP0784466A1 (en) 1997-07-23
MA23687A1 (fr) 1996-07-01
NO971491D0 (no) 1997-04-02
US20010006667A1 (en) 2001-07-05
US5667492A (en) 1997-09-16
CA2201872A1 (en) 1996-04-18
AU3961295A (en) 1996-05-02
KR970705976A (ko) 1997-11-03
FI971440L (fi) 1997-04-07
IL115495A0 (en) 1996-01-19
WO1996010989A1 (en) 1996-04-18
PT784466E (pt) 2002-06-28
DE69525634T2 (de) 2002-08-29
CO4480018A1 (es) 1997-07-09
FI971440A0 (fi) 1997-04-07
JPH10507178A (ja) 1998-07-14
DK0784466T3 (da) 2002-04-22

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