ES2170788T3 - Procedimiento para la obtencion de inmunoglobulinas a partir de fracciones que resultan de plasma sanguineo humano. - Google Patents
Procedimiento para la obtencion de inmunoglobulinas a partir de fracciones que resultan de plasma sanguineo humano.Info
- Publication number
- ES2170788T3 ES2170788T3 ES95810596T ES95810596T ES2170788T3 ES 2170788 T3 ES2170788 T3 ES 2170788T3 ES 95810596 T ES95810596 T ES 95810596T ES 95810596 T ES95810596 T ES 95810596T ES 2170788 T3 ES2170788 T3 ES 2170788T3
- Authority
- ES
- Spain
- Prior art keywords
- immunoglobulin
- obtaining
- procedure
- blood plasma
- plasma
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/081—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
- C07K16/082—Hepadnaviridae, e.g. hepatitis B virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
- C07K16/065—Purification, fragmentation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
- C07K16/1282—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Clostridium (G)
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Virology (AREA)
- Veterinary Medicine (AREA)
- Analytical Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
SE OBTIENEN PREPARADOS DE INMUNOGLOBULINA DE ALTA VALORACION, LLEVANDO A CABO SUCESIVAMENTE LOS SIGUIENTES PASOS: - FRACCIONAMIENTO DE PLASMA SANGUINEO A PARTIR DE UN CONJUNTO DE PLASMA, MEDIANTE EL CUAL SE SEPARA AL MENOS LA FRACCION DE VALOR INDUSTRIAL, QUE CONTIENE ESENCIALMENTE LA INMUNOGLOBULINA G POLICLONAL, OBTENIENDO AL MENOS UNA FRACCION RESIDUAL, - OBTENCION DE UNA SOLUCION PROTEINICA A PARTIR DE LOS COMPONENTES PROTEINICOS QUE ESTAN CONTENIDOS EN LA FRACCION RESIDUAL OBTENIDA EN EL PASO A) O EN SUBFRACCIONES DE ELLA, Y - AL MENOS UNA ETAPA DE CROMATOGRAFIA DE AFINIDAD CON LA SOLUCION PROTEINICA RESULTANTE CON LIGANDOS INMOVILIZADOS DE AL MENOS UN TIPO DE LIGANDO, DISOLVIENDO LAS PROTEINAS PLASMATICAS ESPECIFICAMENTE UNIDAS Y PASANDOLAS COMO COMPONENTES ACTIVOS A UN PREPARADO DE INMUNOGLOBULINA DE ALTA VALORACION. LAS INMUNOGLOBLINAS OBTENIDAS SE PUEDEN PROCESAR PARA DAR UN PRODUCTO ESTABLE. EL PROCEDIMIENTO, QUE OBTIENE UN PREPARADO VALIOSO DE INMUNOGLOBULINA, UTILIZA FRACCIONESPLASMATICAS HUMANAS, QUE SE DESECHABAN HASTA AHORA EN PROCEDIMIENTO CONVENCIONALES E INDUSTRIALES DE FRACCIONAMIENTO DE PLASMA.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP95810596A EP0764658B1 (de) | 1995-09-22 | 1995-09-22 | Verfahren zur Gewinnung von Immunglobulinen aus Fraktionen, die bei der Fraktionierung von menschlichem Blutplasma entstehen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2170788T3 true ES2170788T3 (es) | 2002-08-16 |
Family
ID=8221797
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES95810596T Expired - Lifetime ES2170788T3 (es) | 1995-09-22 | 1995-09-22 | Procedimiento para la obtencion de inmunoglobulinas a partir de fracciones que resultan de plasma sanguineo humano. |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP0764658B1 (es) |
| JP (1) | JP2952572B2 (es) |
| KR (1) | KR100236762B1 (es) |
| CN (1) | CN1089609C (es) |
| AT (1) | ATE211486T1 (es) |
| AU (1) | AU715427B2 (es) |
| BR (1) | BR9603826A (es) |
| CA (1) | CA2185617A1 (es) |
| CZ (1) | CZ286885B6 (es) |
| DE (1) | DE59509979D1 (es) |
| DK (1) | DK0764658T3 (es) |
| ES (1) | ES2170788T3 (es) |
| FI (1) | FI963719A (es) |
| HU (1) | HUP9602570A3 (es) |
| MX (1) | MX9604256A (es) |
| NO (1) | NO963952L (es) |
| NZ (1) | NZ299394A (es) |
| PL (1) | PL316126A1 (es) |
| PT (1) | PT764658E (es) |
| RO (1) | RO117921B1 (es) |
| RU (1) | RU2157240C2 (es) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2531459A1 (es) * | 2013-06-10 | 2015-03-16 | Antonio VILA SANJURJO | Método para la separación física de "traductomas" convolucionados |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1293119B1 (it) * | 1997-06-12 | 1999-02-11 | Mini Ricerca Scient Tecnolog | Processo per la separazione di immunoglobuline specifiche da plasma standard e loro utilizzo per trattamenti terapeutici |
| EP0911037B2 (en) | 1997-10-23 | 2007-06-13 | Mitsubishi Pharma Corporation | Room temperature storable immunoglobulin preparation for intravenous injection |
| CN101035439B (zh) * | 2004-08-20 | 2013-02-06 | 普洛麦提生命科学有限公司 | 通过亲和色谱法进行的连续蛋白质分离和提纯方案 |
| EP2233499A1 (en) * | 2009-03-26 | 2010-09-29 | CSL Behring AG | Antibody composition with altered Fab sialylation |
| WO2010148117A1 (en) * | 2009-06-17 | 2010-12-23 | Scantibodies Laboratory, Inc. | Therapeutic and diagnostic affinity purified specific polyclonal antibodies |
| ITRM20090558A1 (it) * | 2009-11-03 | 2011-05-04 | Michele Pitaro | Procedimento per la produzione di immunoglobuline estratte da plasma umano ad uso terapeutico neutralizzanti il virus di epstein barr e farmaco contenente dette immunoglobuline |
| GB201006753D0 (en) | 2010-04-22 | 2010-06-09 | Biotest Ag | Process for preparing an immunolobulin composition |
| CN103119058A (zh) * | 2010-07-23 | 2013-05-22 | 巴克斯特国际公司 | 由血浆生产间-α-抑制蛋白(IAIP) |
| FR3018450B1 (fr) * | 2014-03-11 | 2016-04-15 | Lab Francais Du Fractionnement | Procede de preparation de proteines plasmatiques humaines |
| KR20150115639A (ko) * | 2014-04-04 | 2015-10-14 | 전숙영 | 치료용 면역글로불린 제제 제조에 사용되는 산성 완충액, 이를 이용한 치료용 면역글로불린 제제 제조방법 및 이 제조방법으로 제조된 치료용 면역글로불린 제제 |
| GB201413227D0 (en) | 2014-07-25 | 2014-09-10 | Bioproducts Lab Ltd | Process |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4232004A (en) * | 1977-09-21 | 1980-11-04 | American National Red Cross | Antibody-specific solid phase immunoadsorbent, preparation thereof, and antibody purification therewith |
| DE3516119A1 (de) * | 1985-05-04 | 1986-11-06 | Biotest Pharma GmbH, 6000 Frankfurt | Polyvalentes hyperimmunglobulin-praeparat |
| IL90281A (en) * | 1988-06-06 | 1994-10-07 | Miles Inc | Preparations containing MGI antibodies |
-
1995
- 1995-09-22 EP EP95810596A patent/EP0764658B1/de not_active Expired - Lifetime
- 1995-09-22 PT PT95810596T patent/PT764658E/pt unknown
- 1995-09-22 DK DK95810596T patent/DK0764658T3/da active
- 1995-09-22 AT AT95810596T patent/ATE211486T1/de not_active IP Right Cessation
- 1995-09-22 ES ES95810596T patent/ES2170788T3/es not_active Expired - Lifetime
- 1995-09-22 DE DE59509979T patent/DE59509979D1/de not_active Expired - Lifetime
-
1996
- 1996-09-16 CA CA002185617A patent/CA2185617A1/en not_active Abandoned
- 1996-09-16 NZ NZ299394A patent/NZ299394A/en unknown
- 1996-09-18 CZ CZ19962748A patent/CZ286885B6/cs not_active IP Right Cessation
- 1996-09-18 KR KR1019960040589A patent/KR100236762B1/ko not_active IP Right Cessation
- 1996-09-18 PL PL96316126A patent/PL316126A1/xx unknown
- 1996-09-19 AU AU65725/96A patent/AU715427B2/en not_active Ceased
- 1996-09-19 HU HU9602570A patent/HUP9602570A3/hu unknown
- 1996-09-19 RO RO96-01839A patent/RO117921B1/ro unknown
- 1996-09-19 FI FI963719A patent/FI963719A/fi unknown
- 1996-09-20 NO NO963952A patent/NO963952L/no unknown
- 1996-09-20 BR BR9603826A patent/BR9603826A/pt active Search and Examination
- 1996-09-21 CN CN96122771A patent/CN1089609C/zh not_active Expired - Fee Related
- 1996-09-23 MX MX9604256A patent/MX9604256A/es unknown
- 1996-09-23 RU RU96118916/14A patent/RU2157240C2/ru not_active IP Right Cessation
- 1996-09-24 JP JP8251895A patent/JP2952572B2/ja not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2531459A1 (es) * | 2013-06-10 | 2015-03-16 | Antonio VILA SANJURJO | Método para la separación física de "traductomas" convolucionados |
Also Published As
| Publication number | Publication date |
|---|---|
| NO963952L (no) | 1997-03-24 |
| BR9603826A (pt) | 1998-06-02 |
| DK0764658T3 (da) | 2002-04-22 |
| JPH09124508A (ja) | 1997-05-13 |
| DE59509979D1 (de) | 2002-02-07 |
| CZ286885B6 (en) | 2000-07-12 |
| PL316126A1 (en) | 1997-04-01 |
| NZ299394A (en) | 1997-12-19 |
| HUP9602570A2 (en) | 1997-08-28 |
| HU9602570D0 (en) | 1996-11-28 |
| ATE211486T1 (de) | 2002-01-15 |
| KR100236762B1 (ko) | 2000-01-15 |
| RO117921B1 (ro) | 2002-09-30 |
| CN1089609C (zh) | 2002-08-28 |
| MX9604256A (es) | 1998-04-30 |
| AU6572596A (en) | 1997-04-10 |
| FI963719A0 (fi) | 1996-09-19 |
| FI963719A (fi) | 1997-03-23 |
| PT764658E (pt) | 2002-06-28 |
| EP0764658B1 (de) | 2002-01-02 |
| JP2952572B2 (ja) | 1999-09-27 |
| KR970015745A (ko) | 1997-04-28 |
| EP0764658A1 (de) | 1997-03-26 |
| CA2185617A1 (en) | 1997-03-23 |
| RU2157240C2 (ru) | 2000-10-10 |
| NO963952D0 (no) | 1996-09-20 |
| AU715427B2 (en) | 2000-02-03 |
| CN1153063A (zh) | 1997-07-02 |
| CZ274896A3 (en) | 1997-04-16 |
| HUP9602570A3 (en) | 1998-01-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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