ES2170276T3 - Particulas marcadas por un codigo permitiendo el seguimiento de secuencias de procedimientos industriales durante la preparacion de bibliotecas de compuestos de quimica combinatoria. - Google Patents
Particulas marcadas por un codigo permitiendo el seguimiento de secuencias de procedimientos industriales durante la preparacion de bibliotecas de compuestos de quimica combinatoria.Info
- Publication number
- ES2170276T3 ES2170276T3 ES96935090T ES96935090T ES2170276T3 ES 2170276 T3 ES2170276 T3 ES 2170276T3 ES 96935090 T ES96935090 T ES 96935090T ES 96935090 T ES96935090 T ES 96935090T ES 2170276 T3 ES2170276 T3 ES 2170276T3
- Authority
- ES
- Spain
- Prior art keywords
- libraries
- sequences
- follow
- preparation
- chemical compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000002245 particle Substances 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 238000001311 chemical methods and process Methods 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
- C07K1/045—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers using devices to improve synthesis, e.g. reactors, special vessels
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
- C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00497—Features relating to the solid phase supports
- B01J2219/005—Beads
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00497—Features relating to the solid phase supports
- B01J2219/00502—Particles of irregular geometry
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/0054—Means for coding or tagging the apparatus or the reagents
- B01J2219/00547—Bar codes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/0054—Means for coding or tagging the apparatus or the reagents
- B01J2219/00547—Bar codes
- B01J2219/00549—2-dimensional
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/0054—Means for coding or tagging the apparatus or the reagents
- B01J2219/00554—Physical means
- B01J2219/00556—Perforations
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/0054—Means for coding or tagging the apparatus or the reagents
- B01J2219/00554—Physical means
- B01J2219/00558—Cuts-out
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/0054—Means for coding or tagging the apparatus or the reagents
- B01J2219/00554—Physical means
- B01J2219/0056—Raised or sunken areas
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00585—Parallel processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00592—Split-and-pool, mix-and-divide processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00596—Solid-phase processes
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B70/00—Tags or labels specially adapted for combinatorial chemistry or libraries, e.g. fluorescent tags or bar codes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Analytical Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Pyrane Compounds (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Powder Metallurgy (AREA)
- Auxiliary Devices For And Details Of Packaging Control (AREA)
- Manufacture And Refinement Of Metals (AREA)
- Control And Other Processes For Unpacking Of Materials (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Saccharide Compounds (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
UNA PARTICULA DE SOPORTE SOLIDA (3) ADAPTADA PARA SU USO EN TECNICAS DE QUIMICA COMBINATORIA CARACTERIZADA EN QUE LA PARTICULA (3) ES MARCADA CON UN CODIGO LEGIBLE POR MAQUINA (4, 5, 6, 7, 8).
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9521943.2A GB9521943D0 (en) | 1995-10-26 | 1995-10-26 | Coded particles for process sequence tracking in combinatorial compound library preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2170276T3 true ES2170276T3 (es) | 2002-08-01 |
Family
ID=10782942
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES96935090T Expired - Lifetime ES2170276T3 (es) | 1995-10-26 | 1996-10-25 | Particulas marcadas por un codigo permitiendo el seguimiento de secuencias de procedimientos industriales durante la preparacion de bibliotecas de compuestos de quimica combinatoria. |
Country Status (11)
Country | Link |
---|---|
EP (2) | EP0863797B1 (es) |
JP (1) | JP2000516195A (es) |
AT (1) | ATE210496T1 (es) |
AU (1) | AU696505B2 (es) |
CA (1) | CA2235837A1 (es) |
DE (1) | DE69618001T2 (es) |
DK (1) | DK0863797T3 (es) |
ES (1) | ES2170276T3 (es) |
GB (2) | GB9521943D0 (es) |
PT (1) | PT863797E (es) |
WO (1) | WO1997015390A1 (es) |
Families Citing this family (102)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5874214A (en) | 1995-04-25 | 1999-02-23 | Irori | Remotely programmable matrices with memories |
US6340588B1 (en) | 1995-04-25 | 2002-01-22 | Discovery Partners International, Inc. | Matrices with memories |
US6017496A (en) | 1995-06-07 | 2000-01-25 | Irori | Matrices with memories and uses thereof |
US6416714B1 (en) * | 1995-04-25 | 2002-07-09 | Discovery Partners International, Inc. | Remotely programmable matrices with memories |
US6284459B1 (en) | 1995-04-25 | 2001-09-04 | Discovery Partners International | Solid support matrices with memories and combinatorial libraries therefrom |
US6025129A (en) | 1995-04-25 | 2000-02-15 | Irori | Remotely programmable matrices with memories and uses thereof |
US6329139B1 (en) | 1995-04-25 | 2001-12-11 | Discovery Partners International | Automated sorting system for matrices with memory |
US5741462A (en) | 1995-04-25 | 1998-04-21 | Irori | Remotely programmable matrices with memories |
US6319668B1 (en) | 1995-04-25 | 2001-11-20 | Discovery Partners International | Method for tagging and screening molecules |
EA199700257A1 (ru) | 1995-04-25 | 1998-12-24 | Ирори | Матрицы с памятью, программируемые на расстоянии, и их использование |
US6331273B1 (en) | 1995-04-25 | 2001-12-18 | Discovery Partners International | Remotely programmable matrices with memories |
US6352854B1 (en) | 1995-04-25 | 2002-03-05 | Discovery Partners International, Inc. | Remotely programmable matrices with memories |
US6100026A (en) * | 1995-04-25 | 2000-08-08 | Irori | Matrices with memories and uses thereof |
US5961923A (en) * | 1995-04-25 | 1999-10-05 | Irori | Matrices with memories and uses thereof |
GB2326152B (en) * | 1996-03-07 | 2000-06-28 | Imperial College | A composite for combinatorial organic synthesis |
GB2337269B (en) * | 1997-04-17 | 2002-10-09 | Zeneca Ltd | Method for the preparation of a chemical library |
GB9707742D0 (en) * | 1997-04-17 | 1997-06-04 | Zeneca Ltd | Methods |
GB9707741D0 (en) * | 1997-04-17 | 1997-06-04 | Zeneca Ltd | Process |
US6096496A (en) * | 1997-06-19 | 2000-08-01 | Frankel; Robert D. | Supports incorporating vertical cavity emitting lasers and tracking apparatus for use in combinatorial synthesis |
WO1999004895A1 (en) * | 1997-07-24 | 1999-02-04 | Argonaut Technologies, Inc. | Compositions for the storage and delivery of solid phase reactive particles and methods of using the same |
US6960457B1 (en) * | 1997-09-04 | 2005-11-01 | Stanford University | Reversible immobilization of arginine-tagged moieties on a silicate surface |
GB9814259D0 (en) * | 1998-07-02 | 1998-09-02 | Univ Hertfordshire | Improvements to the fabrication and method of use of coded particles in the field of combinatorial chemistry |
GB2334347B (en) * | 1998-02-13 | 2001-02-28 | Univ Hertfordshire | An improved method of fabricating coded particles |
WO1999041006A1 (en) * | 1998-02-13 | 1999-08-19 | University Of Hertfordshire | An improved method of fabricating coded particles |
WO1999047254A1 (en) * | 1998-03-13 | 1999-09-23 | Central Research Laboratories Limited | Apparatus for, and method of, manufacturing a plurality of uniquely labelled articles |
GB9808783D0 (en) * | 1998-04-25 | 1998-06-24 | Central Research Lab Ltd | Labelling of small articles |
WO1999067641A2 (en) | 1998-06-24 | 1999-12-29 | Illumina, Inc. | Decoding of array sensors with microspheres |
GB9820163D0 (en) * | 1998-09-17 | 1998-11-11 | Sentec Ltd | Micro-fabricated coded labels, reading systems and their applications |
EP1169123A1 (en) * | 1999-04-09 | 2002-01-09 | Glaxo Group Limited | Encoding scheme for solid phase chemical libraries |
US6908737B2 (en) | 1999-04-15 | 2005-06-21 | Vitra Bioscience, Inc. | Systems and methods of conducting multiplexed experiments |
CA2366093A1 (en) * | 1999-04-15 | 2000-10-26 | Ilya Ravkin | Combinatorial chemical library supports having indicia at coding positions and methods of use |
US7253435B2 (en) | 1999-04-15 | 2007-08-07 | Millipore Corporation | Particles with light-polarizing codes |
CZ301174B6 (cs) | 1999-04-16 | 2009-11-25 | Biocartis Sa | Kódovaný mikronosic a zpusob jeho prípravy a ctení, zpusob detekce analytu a chemická knihovna |
US7225082B1 (en) | 1999-10-01 | 2007-05-29 | Oxonica, Inc. | Colloidal rod particles as nanobar codes |
US7045049B1 (en) | 1999-10-01 | 2006-05-16 | Nanoplex Technologies, Inc. | Method of manufacture of colloidal rod particles as nanobar codes |
US6919009B2 (en) | 1999-10-01 | 2005-07-19 | Nanoplex Technologies, Inc. | Method of manufacture of colloidal rod particles as nanobarcodes |
DE60107231T2 (de) * | 2000-04-19 | 2005-12-22 | 3D Molecular Sciences Ltd., Harston | Verfahren zur herstellung von kodierten teilchen |
JP2004537712A (ja) | 2000-10-18 | 2004-12-16 | バーチャル・アレイズ・インコーポレーテッド | 多重細胞分析システム |
US7811768B2 (en) * | 2001-01-26 | 2010-10-12 | Aviva Biosciences Corporation | Microdevice containing photorecognizable coding patterns and methods of using and producing the same |
US7015047B2 (en) | 2001-01-26 | 2006-03-21 | Aviva Biosciences Corporation | Microdevices having a preferential axis of magnetization and uses thereof |
US7572642B2 (en) | 2001-04-18 | 2009-08-11 | Ambrigen, Llc | Assay based on particles, which specifically bind with targets in spatially distributed characteristic patterns |
GB0109545D0 (en) * | 2001-04-18 | 2001-06-06 | Scient Generics Ltd | Chemical libraries based on coded particles |
GB0109746D0 (en) * | 2001-04-18 | 2001-06-13 | Scient Generics Ltd | Chemical libraries based on coded particles |
GB0111470D0 (en) * | 2001-05-10 | 2001-07-04 | Scient Generics Ltd | Homogenous photoresist functionalisation |
CA2466164A1 (en) * | 2001-10-30 | 2003-05-08 | Nanomics Biosystems Pty, Ltd. | Device and methods for directed synthesis of chemical libraries |
NZ537729A (en) * | 2002-06-21 | 2006-07-28 | Stephen D Nightingale | Multi-functional product markers and methods for making and using the same |
US7923260B2 (en) | 2002-08-20 | 2011-04-12 | Illumina, Inc. | Method of reading encoded particles |
US7164533B2 (en) | 2003-01-22 | 2007-01-16 | Cyvera Corporation | Hybrid random bead/chip based microarray |
US7872804B2 (en) | 2002-08-20 | 2011-01-18 | Illumina, Inc. | Encoded particle having a grating with variations in the refractive index |
US7901630B2 (en) | 2002-08-20 | 2011-03-08 | Illumina, Inc. | Diffraction grating-based encoded microparticle assay stick |
US7508608B2 (en) | 2004-11-17 | 2009-03-24 | Illumina, Inc. | Lithographically fabricated holographic optical identification element |
US7900836B2 (en) | 2002-08-20 | 2011-03-08 | Illumina, Inc. | Optical reader system for substrates having an optically readable code |
US7441703B2 (en) | 2002-08-20 | 2008-10-28 | Illumina, Inc. | Optical reader for diffraction grating-based encoded optical identification elements |
US20040058457A1 (en) * | 2002-08-29 | 2004-03-25 | Xueying Huang | Functionalized nanoparticles |
US20100255603A9 (en) | 2002-09-12 | 2010-10-07 | Putnam Martin A | Method and apparatus for aligning microbeads in order to interrogate the same |
US7092160B2 (en) | 2002-09-12 | 2006-08-15 | Illumina, Inc. | Method of manufacturing of diffraction grating-based optical identification element |
EP1575707A1 (en) | 2002-09-12 | 2005-09-21 | Cyvera Corporation | Method and apparatus for aligning elongated microbeads in order to interrogate the same |
WO2004025563A1 (en) | 2002-09-12 | 2004-03-25 | Cyvera Corporation | Diffraction grating-based encoded micro-particles for multiplexed experiments |
WO2004038037A2 (en) * | 2002-09-20 | 2004-05-06 | Intel Corporation | Controlled alignment of nano-barcodes encoding specific information for scanning probe microscopy (spm) reading |
US7361821B2 (en) | 2002-09-20 | 2008-04-22 | Intel Corporation | Controlled alignment of nanobarcodes encoding specific information for scanning probe microscopy (SPM) reading |
WO2004028682A2 (en) * | 2002-09-27 | 2004-04-08 | Carlsberg A/S | Spatially encoded polymer matrix |
GB2393784B (en) * | 2002-10-03 | 2005-06-15 | Toshiba Res Europ Ltd | An identification tag and method of making an identification tag |
GB2393785B (en) | 2002-10-03 | 2005-08-31 | Toshiba Res Europ Ltd | Method of making a free standing structure |
US7312257B2 (en) | 2003-01-23 | 2007-12-25 | General Electric Company | Polymer encapsulation of high aspect ratio materials and methods of making same |
GB2405013B (en) * | 2003-08-11 | 2006-02-15 | Toshiba Res Europ Ltd | A security marker and security marking method |
US7488451B2 (en) | 2003-09-15 | 2009-02-10 | Millipore Corporation | Systems for particle manipulation |
US7869011B2 (en) | 2003-12-22 | 2011-01-11 | Novo Norkisk A/S | Apparatus and methods for analysis and sorting of particles such as polymer beads |
WO2005061094A1 (en) | 2003-12-22 | 2005-07-07 | Versamatrix A/S | Identification of encoded beads |
US7433123B2 (en) | 2004-02-19 | 2008-10-07 | Illumina, Inc. | Optical identification element having non-waveguide photosensitive substrate with diffraction grating therein |
US20050277710A1 (en) * | 2004-06-14 | 2005-12-15 | Joyce Richard P | Tagged resin, method of making a tagged resin, and articles made therefrom |
WO2006020363A2 (en) | 2004-07-21 | 2006-02-23 | Illumina, Inc. | Method and apparatus for drug product tracking using encoded optical identification elements |
CA2587674A1 (en) | 2004-11-16 | 2006-05-26 | Illumina, Inc. | Method and apparatus for reading coded microbeads |
WO2006055735A2 (en) | 2004-11-16 | 2006-05-26 | Illumina, Inc | Scanner having spatial light modulator |
US7604173B2 (en) | 2004-11-16 | 2009-10-20 | Illumina, Inc. | Holographically encoded elements for microarray and other tagging labeling applications, and method and apparatus for making and reading the same |
WO2006061600A1 (en) * | 2004-12-07 | 2006-06-15 | University Of Southampton | Particles for use as a solid support and process for their preparation |
GB2422686A (en) * | 2004-12-07 | 2006-08-02 | Univ Southampton | Preparation of solid support particles for chemical reactions |
JP5452922B2 (ja) | 2005-09-13 | 2014-03-26 | アフィメトリックス・インコーポレーテッド | コード化されたマイクロ粒子 |
US8178278B2 (en) | 2005-09-13 | 2012-05-15 | Affymetrix, Inc. | Miniaturized microparticles |
US7623624B2 (en) | 2005-11-22 | 2009-11-24 | Illumina, Inc. | Method and apparatus for labeling using optical identification elements characterized by X-ray diffraction |
EP2384811A1 (en) | 2006-01-11 | 2011-11-09 | Novo Nordisk A/S | A spherical encoded bead with an ultrasonic identification chip |
US7830575B2 (en) | 2006-04-10 | 2010-11-09 | Illumina, Inc. | Optical scanner with improved scan time |
JP4803125B2 (ja) * | 2007-05-10 | 2011-10-26 | ソニー株式会社 | ビーズ群と該ビーズ群の作製方法、並びにビーズ群を用いる方法 |
EP1995329B1 (en) | 2007-05-10 | 2013-09-25 | Sony Corporation | Method for sequencing nucleic acids |
JP4973993B2 (ja) * | 2007-07-23 | 2012-07-11 | 財団法人生産技術研究奨励会 | マイクロビーズの配列装置における解放装置及びその解放装置の設定方法 |
GB0725306D0 (en) * | 2007-12-28 | 2008-02-06 | Pronostics Ltd | Improved microparticles |
JP2009174954A (ja) * | 2008-01-23 | 2009-08-06 | Fujitsu Ltd | コード化粒子 |
JP4582224B2 (ja) | 2008-05-02 | 2010-11-17 | ソニー株式会社 | マイクロビーズ作製方法及びマイクロビーズ |
US9182406B2 (en) | 2008-08-04 | 2015-11-10 | Biodesy, Inc. | Nonlinear optical detection of molecules comprising an unnatural amino acid possessing a hyperpolarizability |
EP2312393A1 (en) * | 2009-10-14 | 2011-04-20 | Biocartis SA | Method for producing microparticles |
US9428789B2 (en) | 2011-03-21 | 2016-08-30 | Biodesy, Inc. | Classification of kinase inhibitors using nonlinear optical techniques |
US9139863B2 (en) | 2012-03-16 | 2015-09-22 | Genentech, Inc. | Engineered conformationally-stabilized proteins |
KR20140142293A (ko) | 2012-03-16 | 2014-12-11 | 제넨테크, 인크. | 조작된 입체형태적으로-안정화된 단백질 |
GB2517857A (en) | 2012-04-25 | 2015-03-04 | Biodesy Inc | Methods for detecting allosteric modulators of proteins |
US10436778B2 (en) | 2013-03-15 | 2019-10-08 | Plexbio Co., Ltd. | Methods and systems for multiplex assays |
CN106659146B (zh) | 2014-05-05 | 2020-06-23 | 再生元制药公司 | 人源化c5和c3动物 |
WO2016106286A1 (en) | 2014-12-23 | 2016-06-30 | Biodesy, Inc. | Attachment of proteins to interfaces for use in nonlinear optical detection |
TWI737614B (zh) | 2015-06-11 | 2021-09-01 | 博錸生技股份有限公司 | 已編碼微載體及其製造方法以及用以進行多工分析之包含該等已編碼微載體之套件 |
EP3405587A4 (en) | 2015-12-23 | 2019-10-30 | Moonshot Pharma LLC | METHOD FOR TRIGGERING AN IMMUNE REACTION THROUGH READ THROUGH PROMOTION OF A PREVIOUS TERMINATION CODON |
EP3513186A4 (en) | 2016-09-16 | 2020-04-29 | Plexbio Co., Ltd. | METHODS AND SYSTEMS FOR MULTIPLEX TESTS |
CN110494168B (zh) | 2017-02-27 | 2023-02-03 | 再生元制药公司 | 肾病症和肝病症的人源化模型 |
US11654135B2 (en) | 2017-06-22 | 2023-05-23 | Moonshot Pharma Llc | Methods for treating colon cancer with compositions comprising amlexanox and immune checkpoint inhibitors |
JP7252354B2 (ja) * | 2019-01-23 | 2023-04-04 | ビージーアイ シェンチェン | マイクロビーズ |
Family Cites Families (9)
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---|---|---|---|---|
US4053433A (en) * | 1975-02-19 | 1977-10-11 | Minnesota Mining And Manufacturing Company | Method of tagging with color-coded microparticles |
CA1056653A (en) * | 1975-11-10 | 1979-06-19 | Edward J. Stevens | Color-coded identifier microparticles |
US4390452A (en) * | 1979-08-20 | 1983-06-28 | Minnesota Mining & Manufacturing Company | Microparticles with visual identifying means |
US4631211A (en) * | 1985-03-25 | 1986-12-23 | Scripps Clinic & Research Foundation | Means for sequential solid phase organic synthesis and methods using the same |
US4767205A (en) * | 1986-01-28 | 1988-08-30 | Flow Cytometry Standards Corporation | Composition and method for hidden identification |
US5770358A (en) * | 1991-09-18 | 1998-06-23 | Affymax Technologies N.V. | Tagged synthetic oligomer libraries |
HUT73150A (en) * | 1992-11-06 | 1996-06-28 | Chiron Mimotopes Pty Ltd | Modular polymer and support for the synthesis thereof |
US5429392A (en) * | 1993-06-18 | 1995-07-04 | Loving; Charles D. | Composite microdot and method |
GB2318666B (en) * | 1994-04-25 | 1998-07-15 | Univ Hertfordshire | Coded items for labelling objects |
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1995
- 1995-10-26 GB GBGB9521943.2A patent/GB9521943D0/en active Pending
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1996
- 1996-10-25 DK DK96935090T patent/DK0863797T3/da active
- 1996-10-25 PT PT96935090T patent/PT863797E/pt unknown
- 1996-10-25 AU AU73184/96A patent/AU696505B2/en not_active Ceased
- 1996-10-25 JP JP09516411A patent/JP2000516195A/ja not_active Ceased
- 1996-10-25 CA CA002235837A patent/CA2235837A1/en not_active Abandoned
- 1996-10-25 AT AT96935090T patent/ATE210496T1/de not_active IP Right Cessation
- 1996-10-25 DE DE69618001T patent/DE69618001T2/de not_active Expired - Fee Related
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- 1996-10-25 EP EP96935090A patent/EP0863797B1/en not_active Expired - Lifetime
- 1996-10-25 EP EP00105243A patent/EP1018365A3/en not_active Withdrawn
- 1996-10-25 ES ES96935090T patent/ES2170276T3/es not_active Expired - Lifetime
- 1996-10-25 GB GB9622249A patent/GB2306484B/en not_active Expired - Fee Related
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DK0863797T3 (da) | 2002-04-15 |
AU7318496A (en) | 1997-05-15 |
EP1018365A9 (en) | 2001-05-16 |
AU696505B2 (en) | 1998-09-10 |
WO1997015390A1 (en) | 1997-05-01 |
EP1018365A8 (en) | 2001-03-28 |
PT863797E (pt) | 2002-05-31 |
EP1018365A2 (en) | 2000-07-12 |
GB9622249D0 (en) | 1996-12-18 |
GB9521943D0 (en) | 1996-01-03 |
GB2306484B (en) | 1997-09-24 |
DE69618001T2 (de) | 2002-08-14 |
EP1018365A3 (en) | 2000-10-11 |
DE69618001D1 (de) | 2002-01-24 |
EP0863797A1 (en) | 1998-09-16 |
ATE210496T1 (de) | 2001-12-15 |
JP2000516195A (ja) | 2000-12-05 |
GB2306484A (en) | 1997-05-07 |
CA2235837A1 (en) | 1997-05-01 |
EP0863797B1 (en) | 2001-12-12 |
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