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ES2162336T3 - Modulo de espectroscopia de correlacion de fluorescencia para un microscopio. - Google Patents

Modulo de espectroscopia de correlacion de fluorescencia para un microscopio.

Info

Publication number
ES2162336T3
ES2162336T3 ES97949965T ES97949965T ES2162336T3 ES 2162336 T3 ES2162336 T3 ES 2162336T3 ES 97949965 T ES97949965 T ES 97949965T ES 97949965 T ES97949965 T ES 97949965T ES 2162336 T3 ES2162336 T3 ES 2162336T3
Authority
ES
Spain
Prior art keywords
microscope
correlation spectroscopy
fluorescence correlation
spectroscopy module
module
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97949965T
Other languages
English (en)
Inventor
Michael Tewes
Jorg Langowski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Deutsches Krebsforschungszentrum DKFZ
Original Assignee
Deutsches Krebsforschungszentrum DKFZ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7813190&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2162336(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Deutsches Krebsforschungszentrum DKFZ filed Critical Deutsches Krebsforschungszentrum DKFZ
Application granted granted Critical
Publication of ES2162336T3 publication Critical patent/ES2162336T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
    • G01N21/6458—Fluorescence microscopy
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/16—Microscopes adapted for ultraviolet illumination ; Fluorescence microscopes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N2021/6417—Spectrofluorimetric devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N2021/6463—Optics
    • G01N2021/6471—Special filters, filter wheel

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Optics & Photonics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Microscoopes, Condenser (AREA)

Abstract

SE PROPONE UN MODULO (1) PARA SU ACOPLAMIENTO A UN MICROSCOPIO (3), POR MEDIO DEL CUAL PUEDE UTILIZARSE EL MICROSCOPIO COMO ESPECTROSCOPIA DE CORRELACION DE FLUORESCENCIA.
ES97949965T 1996-11-29 1997-11-26 Modulo de espectroscopia de correlacion de fluorescencia para un microscopio. Expired - Lifetime ES2162336T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19649605A DE19649605A1 (de) 1996-11-29 1996-11-29 Fluoreszenzkorrelationsspektroskopiemodul für ein Mikroskop

Publications (1)

Publication Number Publication Date
ES2162336T3 true ES2162336T3 (es) 2001-12-16

Family

ID=7813190

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97949965T Expired - Lifetime ES2162336T3 (es) 1996-11-29 1997-11-26 Modulo de espectroscopia de correlacion de fluorescencia para un microscopio.

Country Status (7)

Country Link
US (1) US20020121610A1 (es)
EP (1) EP0941470B1 (es)
JP (1) JP2001505997A (es)
AT (1) ATE207614T1 (es)
DE (2) DE19649605A1 (es)
ES (1) ES2162336T3 (es)
WO (1) WO1998023944A1 (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7498164B2 (en) 1998-05-16 2009-03-03 Applied Biosystems, Llc Instrument for monitoring nucleic acid sequence amplification reaction
US6818437B1 (en) 1998-05-16 2004-11-16 Applera Corporation Instrument for monitoring polymerase chain reaction of DNA
CN1201016C (zh) * 1998-05-16 2005-05-11 Pe公司(Ny) 用于监测dna聚合酶链反应的仪器
DE19949658A1 (de) * 1999-10-14 2001-05-10 Deutsches Krebsforsch Verfahren und Vorrichtung zur Messung von Fluoreszenz-Kreuzkorrelationen
DE19951188B4 (de) * 1999-10-22 2013-04-25 Carl Zeiss Microscopy Gmbh Verfahren und Einrichtung zur Aufzeichnung von Impulssignalen
DE10008594B4 (de) * 2000-02-22 2018-09-20 Carl Zeiss Microscopy Gmbh Einrichtung und Verfahren zur ortsaufgelösten Fluoreszenz-Korrelations-Spektroskopie
DE10115309A1 (de) * 2001-03-28 2002-10-02 Gnothis Holding Sa Ecublens Mikroskopanordnung zur Fluoreszenzspektorskopie, insbesondere Fluoreszenzkorrelationsspektroskopie
US20040238730A1 (en) * 2001-05-07 2004-12-02 Jorg Langowski Fluorescence fluctuation microscope analytical module or scanning module, method for measurement of fluorescence fluctuation and method and device for adjustment of a fluorescence fluctuation microscope
WO2004106903A1 (ja) * 2003-05-30 2004-12-09 Olympus Corporation 受光ユニットおよびそれを含む測定装置
DE10327486B4 (de) * 2003-06-17 2006-07-20 Leica Microsystems Cms Gmbh Vorrichtung zur Bestimmung gerichteter Transportprozesse
WO2006001259A1 (ja) 2004-06-24 2006-01-05 Olympus Corporation 蛍光測光装置
DE102004051940B4 (de) * 2004-10-25 2008-08-21 Leica Microsystems Cms Gmbh Beleuchtungseinrichtung in einem Mikroskop
WO2006087727A1 (en) * 2005-02-15 2006-08-24 Tata Institute Of Fundamental Research Fluorescence correlation microscopy with real-time alignment readout
DE102005046510B4 (de) 2005-09-29 2022-02-17 Leica Microsystems Cms Gmbh Mikroskopsystem für FCS-Messungen
DE102005059650B4 (de) 2005-12-14 2011-08-18 Leica Microsystems CMS GmbH, 35578 Vorrichtung zur Montage für mehrere Laser und Mikroskop
DE102005059649B4 (de) 2005-12-14 2017-09-07 Leica Microsystems Cms Gmbh Vorrichtung zur Montage für mehrere Laser
DE102006048054A1 (de) 2006-10-11 2008-04-17 Carl Zeiss Microimaging Gmbh Multispektrale Beleuchtungseinrichtung
JP2008249433A (ja) * 2007-03-29 2008-10-16 Kansai Bunri Sogo Gakuen 被験物質に対するプローブの結合親和性を測定する方法及びその利用
DE102008049877A1 (de) * 2008-09-30 2010-04-01 Carl Zeiss Microimaging Gmbh Verfahren zum Auswerten von Korrelationsspektroskopiemessdaten
DE102010016818A1 (de) * 2010-03-16 2011-09-22 Leica Microsystems Cms Gmbh Verfahren und Vorrichtung zur Durchführung von Multipoint-FCS

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4111903A1 (de) * 1991-04-12 1992-10-15 Bayer Ag Spektroskopiekorrelierte licht-rastermikroskopie
JP3082346B2 (ja) * 1991-09-12 2000-08-28 株式会社ニコン 蛍光コンフォーカル顕微鏡
AU5884394A (en) * 1993-01-18 1994-08-15 Evotec Biosystems Gmbh Method and device for assessing the suitability of biopolymers
EP0731371B1 (en) * 1995-03-06 2003-04-16 Perkin-Elmer Limited Microscope stage control

Also Published As

Publication number Publication date
EP0941470B1 (de) 2001-10-24
DE19649605A1 (de) 1998-06-04
JP2001505997A (ja) 2001-05-08
DE59705110D1 (de) 2001-11-29
WO1998023944A1 (de) 1998-06-04
US20020121610A1 (en) 2002-09-05
ATE207614T1 (de) 2001-11-15
EP0941470A1 (de) 1999-09-15

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