ES2134064T3 - HARPAGOPHYTUM PROCUMBENS EXTRACT RICH IN HARPAGOSIDO AND PROCEDURE FOR ITS PREPARATION. - Google Patents
HARPAGOPHYTUM PROCUMBENS EXTRACT RICH IN HARPAGOSIDO AND PROCEDURE FOR ITS PREPARATION.Info
- Publication number
- ES2134064T3 ES2134064T3 ES97918049T ES97918049T ES2134064T3 ES 2134064 T3 ES2134064 T3 ES 2134064T3 ES 97918049 T ES97918049 T ES 97918049T ES 97918049 T ES97918049 T ES 97918049T ES 2134064 T3 ES2134064 T3 ES 2134064T3
- Authority
- ES
- Spain
- Prior art keywords
- harpagosido
- procedure
- preparation
- harpagophytum procumbens
- extract rich
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000284 extract Substances 0.000 title abstract 4
- 241000254191 Harpagophytum procumbens Species 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- KVRQGMOSZKPBNS-FMHLWDFHSA-N Harpagoside Chemical compound O([C@@H]1OC=C[C@@]2(O)[C@H](O)C[C@]([C@@H]12)(C)OC(=O)\C=C\C=1C=CC=CC=1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O KVRQGMOSZKPBNS-FMHLWDFHSA-N 0.000 abstract 1
- KVRQGMOSZKPBNS-BYYMOQGZSA-N Harpagoside Natural products C[C@@]1(C[C@@H](O)[C@@]2(O)C=CO[C@@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@H]12)OC(=O)C=Cc4ccccc4 KVRQGMOSZKPBNS-BYYMOQGZSA-N 0.000 abstract 1
- XNRNNGPBEPRNAR-UHFFFAOYSA-N Thromboxane B2 Natural products CCCCCC(O)C=CC1OC(O)CC(O)C1CC=CCCCC(O)=O XNRNNGPBEPRNAR-UHFFFAOYSA-N 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 150000004787 cysteinyl leucotrienes Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000004936 stimulating effect Effects 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
- XNRNNGPBEPRNAR-JQBLCGNGSA-N thromboxane B2 Chemical compound CCCCC[C@H](O)\C=C\[C@H]1OC(O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O XNRNNGPBEPRNAR-JQBLCGNGSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Botany (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Medical Informatics (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
The disclosure relates to extracts from Harpagophytum procumbens with a high harpagoside content, to processes for producing them, such extracts containing no components capable of stimulating the synthesis of thromboxane B2 and cysteinylleucotrienes, and to pharmaceutical compositions containing such extracts.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19611221 | 1996-03-21 | ||
| DE19651290A DE19651290A1 (en) | 1996-03-21 | 1996-12-10 | Harpagoside-enriched extract from Harpagophytum procumbens and process for its preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2134064T3 true ES2134064T3 (en) | 1999-09-16 |
Family
ID=26024014
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES97918049T Expired - Lifetime ES2134064T3 (en) | 1996-03-21 | 1997-03-21 | HARPAGOPHYTUM PROCUMBENS EXTRACT RICH IN HARPAGOSIDO AND PROCEDURE FOR ITS PREPARATION. |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6280737B1 (en) |
| EP (1) | EP0897302B1 (en) |
| JP (1) | JP3294618B2 (en) |
| AT (1) | ATE181507T1 (en) |
| AU (1) | AU2633297A (en) |
| CA (1) | CA2248092A1 (en) |
| DE (1) | DE19780262D2 (en) |
| ES (1) | ES2134064T3 (en) |
| WO (1) | WO1997034565A2 (en) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1082820C (en) | 1996-05-18 | 2002-04-17 | 芬泽尔伯格股份有限两合公司 | Purified extract of harpagophytum procumbens and/or harpagophytum zeyheri dence, process for its prodn. and its use |
| GB2335919A (en) * | 1998-04-01 | 1999-10-06 | Essential Nutrition Ltd | A method of producing high anti-inflammatory activity extracts from harpagophytum procumbens |
| US6197307B1 (en) * | 1999-03-30 | 2001-03-06 | Essential Nutrition, Ltd. | Method for producing high activity extracts from harpagophytum procumbens |
| KR100415826B1 (en) * | 2000-11-28 | 2004-01-31 | 신준식 | Pharmaceutical preparations containing CIBOTII RHIZOMA and Harpagophytum procumbens DC. as main ingredients |
| KR100416842B1 (en) * | 2000-11-29 | 2004-02-05 | 신준식 | A pharmaceutical preparation for the treatment or prevention of osteoporosis of harpagide-related compound |
| FR2915900B1 (en) * | 2007-05-07 | 2012-08-24 | Burgundy | NEW PROCESS FOR THE PREPARATION OF PURIFIED EXTRACTS OF HARPAGOPHYTUM PROCUMBENS. |
| JP5122924B2 (en) * | 2007-11-29 | 2013-01-16 | 日本メナード化粧品株式会社 | Anti-obesity agent |
| US20110262552A1 (en) * | 2008-10-02 | 2011-10-27 | Guy Chamberland | Compositions Comprising Plant Extracts and Use Thereof for Treating Inflammation |
| TWI583312B (en) * | 2009-08-12 | 2017-05-21 | 梅拉洛伊卡公司 | Dietary supplements and methods for treating pain and inflammation |
| WO2011041542A2 (en) | 2009-09-30 | 2011-04-07 | Ultimaxx, Inc. | Herbal pain killer compositions |
| ITRM20130501A1 (en) * | 2013-09-10 | 2015-03-11 | Aboca Spa Societa Agricola | NEW EXTRACTS OF ARTISAN OF THE DEVIL AND THEIR USES. |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2614791B1 (en) | 1987-05-07 | 1989-07-21 | Moati Roger | MEDICINAL ASSOCIATION BASED ON PLANTS AND TRACE ELEMENTS FOR THE TREATMENT OF RHEUMATISMS AND INFLAMMATORY CONDITIONS |
| KR920005686B1 (en) * | 1989-11-07 | 1992-07-13 | 동국제약 주식회사 | Process for the preparation by extracting of harpagophytum |
| DE3940092A1 (en) | 1989-12-04 | 1991-06-06 | Schwabe Willmar Gmbh & Co | EXTRACT OF BLACKERS OF GINKGO BILOBA, METHOD FOR THE PRODUCTION THEREOF AND THE EXTRACT CONTAINING MEDICAMENT |
| FR2679449B1 (en) * | 1991-07-23 | 1996-07-26 | Daniel Sincholle | NOVEL ANTIPRURIGINOUS COSMETIC PREPARATIONS CONTAINING AN EXTRACT OF HARPAGOPHYTON ROOTS. |
-
1997
- 1997-03-21 EP EP97918049A patent/EP0897302B1/en not_active Expired - Lifetime
- 1997-03-21 ES ES97918049T patent/ES2134064T3/en not_active Expired - Lifetime
- 1997-03-21 US US09/155,043 patent/US6280737B1/en not_active Expired - Lifetime
- 1997-03-21 JP JP53304997A patent/JP3294618B2/en not_active Expired - Fee Related
- 1997-03-21 AU AU26332/97A patent/AU2633297A/en not_active Abandoned
- 1997-03-21 AT AT97918049T patent/ATE181507T1/en active
- 1997-03-21 CA CA002248092A patent/CA2248092A1/en not_active Abandoned
- 1997-03-21 WO PCT/DE1997/000591 patent/WO1997034565A2/en active IP Right Grant
- 1997-03-21 DE DE19780262T patent/DE19780262D2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0897302A2 (en) | 1999-02-24 |
| JP2000501113A (en) | 2000-02-02 |
| US6280737B1 (en) | 2001-08-28 |
| WO1997034565A3 (en) | 1997-10-23 |
| CA2248092A1 (en) | 1997-09-25 |
| WO1997034565A2 (en) | 1997-09-25 |
| AU2633297A (en) | 1997-10-10 |
| ATE181507T1 (en) | 1999-07-15 |
| EP0897302B1 (en) | 1999-06-23 |
| DE19780262D2 (en) | 1999-03-11 |
| JP3294618B2 (en) | 2002-06-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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