ES2128281T1 - Proceso de desesterificacion. - Google Patents
Proceso de desesterificacion.Info
- Publication number
- ES2128281T1 ES2128281T1 ES96938143T ES96938143T ES2128281T1 ES 2128281 T1 ES2128281 T1 ES 2128281T1 ES 96938143 T ES96938143 T ES 96938143T ES 96938143 T ES96938143 T ES 96938143T ES 2128281 T1 ES2128281 T1 ES 2128281T1
- Authority
- ES
- Spain
- Prior art keywords
- tetrachloride
- ceph
- isomer
- substituted
- deesterification process
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 title abstract 2
- 238000007257 deesterification reaction Methods 0.000 title 1
- -1 3-substituted (6R,7R)-7-phenyl-acetamido-ceph-3-em-4-carboxylic acid Chemical class 0.000 abstract 2
- LSNNJFPAIWHDGA-TZMCWYRMSA-N (6r,7r)-8-oxo-7-[(2-phenylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid Chemical class N([C@H]1[C@H]2SCC=C(N2C1=O)C(=O)O)C(=O)CC1=CC=CC=C1 LSNNJFPAIWHDGA-TZMCWYRMSA-N 0.000 abstract 1
- OFDISMSWWNOGFW-UHFFFAOYSA-N 1-(4-ethoxy-3-fluorophenyl)ethanamine Chemical compound CCOC1=CC=C(C(C)N)C=C1F OFDISMSWWNOGFW-UHFFFAOYSA-N 0.000 abstract 1
- 229910021627 Tin(IV) chloride Inorganic materials 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 abstract 1
- HPGGPRDJHPYFRM-UHFFFAOYSA-J tin(iv) chloride Chemical compound Cl[Sn](Cl)(Cl)Cl HPGGPRDJHPYFRM-UHFFFAOYSA-J 0.000 abstract 1
- XJDNKRIXUMDJCW-UHFFFAOYSA-J titanium tetrachloride Chemical compound Cl[Ti](Cl)(Cl)Cl XJDNKRIXUMDJCW-UHFFFAOYSA-J 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
SE PROPORCIONA UN PROCESO EFICIENTE PARA LA DESESTERIFICACION POR APLICACION DE TETRAHALOGENUROS ESPECIALES. APLICANDO ESTE PROCESO, SE HA PREPARADO UN NUEVO COMPUESTO, A SABER, LA CEFESONA, Y ESPECIALMENTE SU ISOMERO - E.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US727895P | 1995-11-06 | 1995-11-06 | |
EP95202992 | 1995-11-06 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2128281T1 true ES2128281T1 (es) | 1999-05-16 |
Family
ID=8220799
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES96938143T Pending ES2128281T1 (es) | 1995-11-06 | 1996-11-06 | Proceso de desesterificacion. |
Country Status (7)
Country | Link |
---|---|
US (1) | US6107481A (es) |
EP (1) | EP0907654B1 (es) |
AT (1) | ATE195125T1 (es) |
AU (1) | AU7567596A (es) |
DE (1) | DE907654T1 (es) |
ES (1) | ES2128281T1 (es) |
WO (1) | WO1997017352A1 (es) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE602004016316D1 (de) | 2003-04-04 | 2008-10-16 | Lundbeck & Co As H | 4-(2-phenylsulfanyl-phenyl)-piperidin-derivate als serotonin-wiederaufnahme-hemmer |
ES2303960T3 (es) | 2003-12-23 | 2008-09-01 | H. Lundbeck A/S | Derivados de 2-(1h-indolilsulfanil)-bencilamina como isrs. |
AR052308A1 (es) | 2004-07-16 | 2007-03-14 | Lundbeck & Co As H | Derivados de 2-(1h-indolilsulfanil)-arilamina y una composicion farmaceutica que contiene al compuesto |
AR054394A1 (es) * | 2005-06-17 | 2007-06-20 | Lundbeck & Co As H | Derivados de 2- (1h-indolilsulfanil)-aril amina |
US7629473B2 (en) | 2005-06-17 | 2009-12-08 | H. Lundbeck A/S | 2-(1H-indolylsulfanyl)-aryl amine derivatives |
AR054393A1 (es) | 2005-06-17 | 2007-06-20 | Lundbeck & Co As H | Derivados de benzo(b)furano y benzo(b)tiofeno, composiciones farmaceuticas que los contienen y su uso en la fabricacion de un medicamento para el tratamiento de enfermedades mediadas por la inhibicion de la reabsorcion de neurotransmisores de amina biogenicos. |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS52106891A (en) * | 1976-03-03 | 1977-09-07 | Shionogi & Co Ltd | Removal of carboxyl protecting group |
DE2725519A1 (de) * | 1977-06-06 | 1978-12-21 | Shionogi & Co | Verfahren zur herstellung freier carbonsaeuren durch esterspaltung |
IL72412A (en) * | 1983-07-22 | 1988-05-31 | Lilly Co Eli | Deesterification of beta-lactam antibiotic esters |
KR0137221B1 (ko) * | 1987-07-13 | 1998-04-25 | 안스 월터 라벤 | 3-엑소메틸렌세팜유도체의 제조방법 |
US5922861A (en) * | 1995-11-06 | 1999-07-13 | Gist-Brocades B.V. | De-esterification process |
-
1996
- 1996-11-06 EP EP96938143A patent/EP0907654B1/en not_active Expired - Lifetime
- 1996-11-06 AT AT96938143T patent/ATE195125T1/de not_active IP Right Cessation
- 1996-11-06 ES ES96938143T patent/ES2128281T1/es active Pending
- 1996-11-06 AU AU75675/96A patent/AU7567596A/en not_active Abandoned
- 1996-11-06 WO PCT/EP1996/004880 patent/WO1997017352A1/en active IP Right Grant
- 1996-11-06 DE DE0907654T patent/DE907654T1/de active Pending
-
1999
- 1999-07-13 US US09/352,288 patent/US6107481A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
AU7567596A (en) | 1997-05-29 |
DE907654T1 (de) | 1999-09-16 |
WO1997017352A1 (en) | 1997-05-15 |
EP0907654A1 (en) | 1999-04-14 |
ATE195125T1 (de) | 2000-08-15 |
US6107481A (en) | 2000-08-22 |
EP0907654B1 (en) | 2000-08-02 |
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