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ES2128125T3 - Reactivo para suprimir interferencias, destinado a usarse en la determinacion de un analito con un complejo metalico luminiscente. - Google Patents

Reactivo para suprimir interferencias, destinado a usarse en la determinacion de un analito con un complejo metalico luminiscente.

Info

Publication number
ES2128125T3
ES2128125T3 ES96108625T ES96108625T ES2128125T3 ES 2128125 T3 ES2128125 T3 ES 2128125T3 ES 96108625 T ES96108625 T ES 96108625T ES 96108625 T ES96108625 T ES 96108625T ES 2128125 T3 ES2128125 T3 ES 2128125T3
Authority
ES
Spain
Prior art keywords
analyte
determination
reagent
luminiscent
intended
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96108625T
Other languages
English (en)
Inventor
Bernhard Dr Eckert
Helmut Dr Lenz
Norbert Dr Franken
Hans-Peter Dr Josel
Beatus Dr Ofenloch-Hahnle
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Application granted granted Critical
Publication of ES2128125T3 publication Critical patent/ES2128125T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5306—Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Peptides Or Proteins (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A UN PROCEDIMIENTO PARA LA DETERMINACION DE UN ANALITO EN UN LIQUIDO DE PRUEBA CON UN COMPLEJO METALICO CON CAPACIDAD DE LUMINISCENCIA COMO GRUPO DE MARCADO ESPECIFICO DE ANALITO PARA LA GENERACION DE UNA SEÑAL DE MEDICION, DONDE SE UTILIZA ADEMAS UN COMPLEJO METALICO NO ESPECIFICO COMO REACTIVO DE ELIMINACION DE PERTURBACION, QUE POSEE UNA ESTRUCTURA MODIFICABLE QUIMICAMENTE CON EL GRUPO DE MARCADO.
ES96108625T 1995-05-31 1996-05-30 Reactivo para suprimir interferencias, destinado a usarse en la determinacion de un analito con un complejo metalico luminiscente. Expired - Lifetime ES2128125T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19519973A DE19519973A1 (de) 1995-05-31 1995-05-31 Entstörungsreagenz für die Bestimmung eines Analyten mit einem lumineszenzfähigen Metallkomplex

Publications (1)

Publication Number Publication Date
ES2128125T3 true ES2128125T3 (es) 1999-05-01

Family

ID=7763332

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96108625T Expired - Lifetime ES2128125T3 (es) 1995-05-31 1996-05-30 Reactivo para suprimir interferencias, destinado a usarse en la determinacion de un analito con un complejo metalico luminiscente.

Country Status (6)

Country Link
US (1) US5888745A (es)
EP (1) EP0747699B1 (es)
JP (1) JP2953501B2 (es)
AT (1) ATE174431T1 (es)
DE (2) DE19519973A1 (es)
ES (1) ES2128125T3 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19703025C2 (de) * 1997-01-28 1999-04-29 Bernd Dr Lorenz Verfahren zur Messung von Konzentrationen sowie zur kontinuierlichen oder diskontinuierlichen Messung des Umsatzes und der Geschwindigkeit enzymatischer oder nichtenzymatischer Reaktionen von Pyrophosphaten und/oder linearen Polyphosphaten unter Ausschluß von zyklischen Polyphosphaten als auch von Orthophosphaten in einer Probe sowie Anwendung des Verfahrens
EP0922958B1 (de) * 1997-12-11 2002-10-02 Roche Diagnostics GmbH Entstörung von diagnostischen Verfahren durch Peptide aus D-Aminosäuren
US6410692B2 (en) * 1998-02-02 2002-06-25 Novadx, Inc. Removal of abundant interfering proteins from a liquid sample using a collapsible affinity matrix
DE19933104A1 (de) * 1999-07-15 2001-01-18 Ingo Klimant Phosphoreszierende Mikro- und Nanopartikel als Referenzstandard und Phosphoreszenzmarker
DE10025145A1 (de) * 2000-05-20 2001-11-22 Presens Prec Sensing Gmbh Phosphoreszierende Polyelektrolytaggregate
US7056321B2 (en) 2000-08-01 2006-06-06 Endius, Incorporated Method of securing vertebrae
DE10048417A1 (de) * 2000-09-29 2002-04-11 Roche Diagnostics Gmbh Verbindungen mit verzweigtem Linker
CN101201354B (zh) * 2006-12-14 2011-11-02 北京科美东雅生物技术有限公司 甲状腺素化学发光免疫分析定量测定试剂盒及制备方法
CN101747381B (zh) * 2008-12-19 2013-09-11 苏州纳凯科技有限公司 用作生物标记物的环金属铱配位化合物
EP3176580A1 (en) * 2015-12-01 2017-06-07 Roche Diagnostics GmbH Method for reduction of interferences in immunoassays
BR112020015686A2 (pt) 2018-03-13 2020-12-08 F. Hoffmann-La Roche Ag Métodos para determinar um analito, para melhorar a especificidade da detecção de um analito e para identificar uma amostra, kit, dispositivo para determinar um analito, usos de uma composição e de pelo menos um primeiro e um segundo composto detector de um analito
CN116948169B (zh) * 2023-06-14 2024-06-28 华南师范大学 一种基于聚赖氨酸的自增强电化学发光探针在水相中快速合成方法及应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5221605A (en) * 1984-10-31 1993-06-22 Igen, Inc. Luminescent metal chelate labels and means for detection
US4810635A (en) * 1986-04-16 1989-03-07 Miles Inc. Specific binding assays employing label analog to reduce sample interferences
CA1339872C (en) * 1987-09-21 1998-05-19 Lyle John Arnold Jr. Homogeneous protection assay
DK0619020T3 (da) * 1991-12-13 2001-02-26 Abbott Lab Bestemmelse af tricykliske, antidepressive lægemidler i nærvær af interfererende stoffer

Also Published As

Publication number Publication date
EP0747699B1 (de) 1998-12-09
DE19519973A1 (de) 1996-12-05
US5888745A (en) 1999-03-30
EP0747699A1 (de) 1996-12-11
DE59600939D1 (de) 1999-01-21
JP2953501B2 (ja) 1999-09-27
ATE174431T1 (de) 1998-12-15
JPH08327548A (ja) 1996-12-13

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