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ES2127479T3 - Procedimiento para preparar 4'-bromometil-2-cianobifenilo. - Google Patents

Procedimiento para preparar 4'-bromometil-2-cianobifenilo.

Info

Publication number
ES2127479T3
ES2127479T3 ES95307560T ES95307560T ES2127479T3 ES 2127479 T3 ES2127479 T3 ES 2127479T3 ES 95307560 T ES95307560 T ES 95307560T ES 95307560 T ES95307560 T ES 95307560T ES 2127479 T3 ES2127479 T3 ES 2127479T3
Authority
ES
Spain
Prior art keywords
cianobifenilo
bromometil
prepare
procedure
cyanobiphenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95307560T
Other languages
English (en)
Inventor
Tadashi Katsura
Hiroshi Shiratani
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumika Fine Chemicals Co Ltd
Original Assignee
Sumika Fine Chemicals Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumika Fine Chemicals Co Ltd filed Critical Sumika Fine Chemicals Co Ltd
Application granted granted Critical
Publication of ES2127479T3 publication Critical patent/ES2127479T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

UN METODO PARA LA PRODUCCION DE 4''-BROMOMETIL-2-CIANOBIFENILO QUE CONSISTE EN TRATAR UN 4''-METIL-2-CIANOBIFENILO CON BR{SUB,2} EN UN SOLVENTE DE HIDROCARBURO HALOGENADO O EN UN SOLVENTE DE ALCANO QUE TENGA DE 5 A 7 ATOMOS DE CARBONO.
ES95307560T 1994-10-27 1995-10-24 Procedimiento para preparar 4'-bromometil-2-cianobifenilo. Expired - Lifetime ES2127479T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP6289079A JP2928982B2 (ja) 1994-10-27 1994-10-27 ４’−ブロモメチル−２−シアノビフェニルの製造法

Publications (1)

Publication Number Publication Date
ES2127479T3 true ES2127479T3 (es) 1999-04-16

Family

ID=17738558

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95307560T Expired - Lifetime ES2127479T3 (es) 1994-10-27 1995-10-24 Procedimiento para preparar 4'-bromometil-2-cianobifenilo.

Country Status (7)

Country Link
US (1) US5621134A (es)
EP (1) EP0709369B1 (es)
JP (1) JP2928982B2 (es)
AT (1) ATE175663T1 (es)
DE (1) DE69507253T2 (es)
DK (1) DK0709369T3 (es)
ES (1) ES2127479T3 (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5892094A (en) * 1997-01-08 1999-04-06 Sumika Fine Chemicals Co., Ltd. Process for preparing 4'-methyl-2-cyanobiphenyl
DE19712339C1 (de) * 1997-03-25 1998-04-09 Clariant Gmbh Verfahren zur Herstellung von in 2'-Stellung substituierten 4-Brommethyl-biphenyl-Verbindungen
FR2771090B1 (fr) * 1997-11-17 2000-02-04 Sanofi Sa Procede de preparation de derives de bromomethyl-biphenyle
DE19757995A1 (de) * 1997-12-29 1999-07-08 Great Lakes Chem Konstanz Gmbh Verfahren zur Herstellung von aromatischen Brommethyl-Verbindungen
CN1285570C (zh) * 2002-06-12 2006-11-22 住友化学株式会社 制备4′－溴甲基－2－氰基联苯的方法
CN1976926A (zh) * 2004-09-02 2007-06-06 特瓦制药工业有限公司 奥美沙坦酯的制备
KR20090102883A (ko) * 2004-09-02 2009-09-30 테바 파마슈티컬 인더스트리즈 리미티드 올메살탄 메독소밀의 정제
US20070054948A1 (en) * 2004-09-02 2007-03-08 Lilach Hedvati Purification of olmesartan medoxomil
US20060148870A1 (en) * 2004-12-30 2006-07-06 Lilach Hedvati Process for preparing olmesartan medoxomil AT pH higher than 2.5
US20060258727A1 (en) * 2005-01-03 2006-11-16 Lilach Hedvati Olmesartan medoxomil with reduced levels of impurities
JP2007526342A (ja) * 2005-01-03 2007-09-13 テバ ファーマシューティカル インダストリーズ リミティド 低レベルの不純物を有するオルメサルタンメドキソミル
EP1705168A1 (en) * 2005-03-21 2006-09-27 Helm AG Improved process for side-chain bromination of alkyl-benzenes
WO2008078340A1 (en) * 2006-12-27 2008-07-03 Calyx Chemicals And Pharmaceuticals Ltd. Process for the separation of 4-bromomethyl-2'-substituted biphenyls from 4,4,-dibromomethyl-2'-substituted biphenyls
CN102557987A (zh) * 2010-12-09 2012-07-11 宜昌长江药业有限公司 一种沙坦类抗高血压药物侧链的制备方法
CN103626677B (zh) * 2013-12-05 2015-07-15 天津大学 制备高纯度溴代沙坦联苯的结晶方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4087473A (en) * 1976-11-03 1978-05-02 The Dow Chemical Company Preferential aliphatic halogenation of ar-substituted alkylbenzenes
DE3044564A1 (de) * 1980-11-26 1982-07-15 Basf Ag, 6700 Ludwigshafen Verfahren zur herstellung von (alpha)-bromacetophenonoximethern
JPS6323868A (ja) 1986-07-11 1988-02-01 イー・アイ・デュポン・ドゥ・ヌムール・アンド・カンパニー アンギオテンシン２受容体遮断性イミダゾ−ル
GB9017482D0 (en) 1990-08-09 1990-09-26 Ici Plc Manufacturing process
GB9017480D0 (en) 1990-08-09 1990-09-26 Ici Plc Chemical process
JP2859791B2 (ja) 1992-01-31 1999-02-24 吉富製薬株式会社 ４−ブロモメチルビフェニル化合物の製造法
US5312958A (en) * 1992-01-31 1994-05-17 Takeda Chemical Industries, Ltd. Process for producing 4-bromomethylbiphenyl compounds
FR2689887B1 (fr) 1992-04-13 1995-06-23 Sanofi Elf Procede de preparation d'un derive de biphenyle.

Also Published As

Publication number Publication date
US5621134A (en) 1997-04-15
EP0709369B1 (en) 1999-01-13
EP0709369A1 (en) 1996-05-01
ATE175663T1 (de) 1999-01-15
JPH08127562A (ja) 1996-05-21
DK0709369T3 (da) 1999-08-30
DE69507253D1 (de) 1999-02-25
DE69507253T2 (de) 1999-05-27
JP2928982B2 (ja) 1999-08-03

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