ES2123550T3 - Procedimiento para producir una composicion de vacuna contra infeccion enterica provocada por la bacteria enterotoxigenica e. coli en los humanos y que es adecuada para vacunacion contra la infeccion enterica/diarrea provocada por la bacteria enterotoxigenica e. coli en humanos. - Google Patents
Procedimiento para producir una composicion de vacuna contra infeccion enterica provocada por la bacteria enterotoxigenica e. coli en los humanos y que es adecuada para vacunacion contra la infeccion enterica/diarrea provocada por la bacteria enterotoxigenica e. coli en humanos.Info
- Publication number
- ES2123550T3 ES2123550T3 ES92906078T ES92906078T ES2123550T3 ES 2123550 T3 ES2123550 T3 ES 2123550T3 ES 92906078 T ES92906078 T ES 92906078T ES 92906078 T ES92906078 T ES 92906078T ES 2123550 T3 ES2123550 T3 ES 2123550T3
- Authority
- ES
- Spain
- Prior art keywords
- bacteria
- coli
- humans
- against enteric
- infection
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 241000894006 Bacteria Species 0.000 title abstract 4
- 206010022678 Intestinal infections Diseases 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 208000015181 infectious disease Diseases 0.000 title abstract 2
- 238000002255 vaccination Methods 0.000 title abstract 2
- 206010012735 Diarrhoea Diseases 0.000 title 1
- 229960005486 vaccine Drugs 0.000 title 1
- 239000000427 antigen Substances 0.000 abstract 2
- 102000036639 antigens Human genes 0.000 abstract 2
- 108091007433 antigens Proteins 0.000 abstract 2
- 241000588724 Escherichia coli Species 0.000 abstract 1
- 108010001506 colonization factor antigens Proteins 0.000 abstract 1
- 230000002779 inactivation Effects 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/025—Enterobacteriales, e.g. Enterobacter
- A61K39/0258—Escherichia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/848—Escherichia
- Y10S435/849—Escherichia coli
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
SE DESCRIBE UN METODO PARA LA PRODUCCION DE UNA COMPOSICION DE VACUNACION CONTRA INFECCIONES ENTERICAS CAUSADAS EN LOS HUMANOS POR LA BACTERIA E. COLI ENTEROTOXIGENA. CEPAS DE E. COLI SELECCIONADAS ENTRE LAS DIFERENTES CADENAS CONOCIDAS, QUE TIENEN CADA UNA LA CAPACIDAD DE PRESENTAR UN CIERTO TIPO DE ANTIGENES DE FACTOR DE COLONIZACION, SE DESARROLLAN EN UN MEDIO DE CULTIVO LIQUIDO. POR ULTIMO, LA CEPA E. COLI FORMALMENTE NEUTRALIZADA, QUE MANTIENE SUBSTANCIALMENTE PRESERVADAS LAS PROPIEDADES ANTIGENAS Y HEMOAGLUTINANTES DE DICHO TIPO DE ANTIGENOS DE FACTOR DE COLONIZACION, SE MEZCLA CON UN EXCIPIENTE O DILUYENTE ACEPTABLE FARMACEUTICAMENTE. ADEMAS SE DESCRIBE UN METODO DE PREVENIR UNA INFECCION ENTERICA CAUSADA EN HUMANOS POR LA BACTERIA E. COLI ENTEROTOXIGENA, EN DONDE UNA COMPOSICION DE VACUNACION, COMPRENDE CEPAS DE E. COLI INACTIVAS Y SE ADMINISTRA AL SER HUMANO PARA PREVENIR DICHA INFECCION.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9100556A SE9100556D0 (sv) | 1991-02-26 | 1991-02-26 | Preparation and use of formalin-killed colonization-factor-antigen (cfa)-expressing e coli organisms for vaccination against enteric infection/diarrhea caused by enterotoxigenic e coli bacteria in humans |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2123550T3 true ES2123550T3 (es) | 1999-01-16 |
Family
ID=20381987
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES92906078T Expired - Lifetime ES2123550T3 (es) | 1991-02-26 | 1992-02-25 | Procedimiento para producir una composicion de vacuna contra infeccion enterica provocada por la bacteria enterotoxigenica e. coli en los humanos y que es adecuada para vacunacion contra la infeccion enterica/diarrea provocada por la bacteria enterotoxigenica e. coli en humanos. |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US6558678B1 (es) |
| EP (1) | EP0573527B1 (es) |
| JP (1) | JP3169608B2 (es) |
| KR (1) | KR100221452B1 (es) |
| AT (1) | ATE170755T1 (es) |
| AU (1) | AU663864B2 (es) |
| BG (1) | BG61683B1 (es) |
| BR (1) | BR9205677A (es) |
| CA (1) | CA2104877C (es) |
| CZ (1) | CZ281556B6 (es) |
| DE (1) | DE69226944T2 (es) |
| DK (1) | DK0573527T3 (es) |
| ES (1) | ES2123550T3 (es) |
| FI (1) | FI108775B (es) |
| HU (1) | HU213924B (es) |
| NO (1) | NO307867B1 (es) |
| OA (1) | OA09865A (es) |
| RO (1) | RO109819B1 (es) |
| RU (1) | RU2127121C1 (es) |
| SE (1) | SE9100556D0 (es) |
| SK (1) | SK280919B6 (es) |
| WO (1) | WO1992014487A1 (es) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7118758B1 (en) * | 1997-01-24 | 2006-10-10 | The United States Of America As Represented By The Secretary Of The Army | Transformed bacteria producing CS6 antigens as vaccines |
| SE9401921D0 (sv) * | 1994-06-03 | 1994-06-03 | Sbl Vaccin Ab | A method of cultivating bacteria |
| US7404961B2 (en) | 1996-08-02 | 2008-07-29 | The United States Of America As Represented By The Secretary Of The Army | Peptides responsive to antibodies against consensus peptide of the CS4-CFA/I family proteins |
| US7094883B1 (en) | 1996-08-02 | 2006-08-22 | The United States Of America As Represented By The Secretary Of The Army | Monoclonal antibody which agglutinates E. coli having the CS4-CFA/I family protein |
| US5994078A (en) * | 1997-07-31 | 1999-11-30 | Maine Medical Center | Stable encapsulated reference nucleic acid and method of making |
| SE515285C2 (sv) * | 1998-12-18 | 2001-07-09 | Sbl Vaccin Ab | Oralt vaccin mot diarré |
| GB0121998D0 (en) * | 2001-09-11 | 2001-10-31 | Acambis Res Ltd | Attenuated bacteria useful in vaccines |
| UA94206C2 (ru) * | 2003-10-31 | 2011-04-26 | Дзе Юніверсіті Оф Брітіш Коламбіа | Бактериальные факторы вирулентности и варианты их применения |
| EP1981536A4 (en) * | 2006-02-01 | 2012-03-14 | Gotovax Ab | COLONIZATIONAL FACTOROUS ENTEROTOXIGENIC ESCHERICHIA COLI IN RECOMBINANT BACTERIA |
| BR112013027845A2 (pt) * | 2011-05-18 | 2017-01-03 | Ajinomoto Kk | Imunoestimulante, ração, método para produzir um imunoestimulante, e, método para imunoestimulação |
| US8926980B2 (en) | 2011-07-11 | 2015-01-06 | Camas Incorporated | Compositions against bacterial toxins |
| CA2846279C (en) | 2011-09-12 | 2021-05-18 | Scandinavian Biopharma Holding Ab | Method for increasing etec cs6 antigen presentation on cell surface and products obtainable thereof |
| WO2013037397A1 (en) * | 2011-09-12 | 2013-03-21 | Scandinavian Biopharma Holding Ab | Vaccine for protection against etec induced diarrhea comprising dmlt. |
| RO132299A3 (ro) | 2017-06-06 | 2018-12-28 | Fântână Raul Sorin | Compoziţie şi metodă de preparare şi evaluare a unui imunogen complex numit i-spga, destinat producerii de proteine imunologic active () |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DD62894A (es) * | ||||
| DE1208038B (de) * | 1963-08-01 | 1965-12-30 | Wellcome Found | Verfahren zur Herstellung von Impfstoffen gegen Coli-Infektionen |
| GB1472624A (en) | 1974-09-02 | 1977-05-04 | Canadian Patents Dev | Enteric disease vaccine |
| US4298597A (en) * | 1979-09-04 | 1981-11-03 | University Of Saskatchewan | Vaccine for diarrhea caused by E. coli |
| US4338298A (en) * | 1980-04-04 | 1982-07-06 | Endowment And Research Foundation At Montana State University | Vaccine for passive immunization against enteric colibacillosis and method of use |
| DK41885A (da) * | 1985-01-31 | 1986-11-13 | Slagteriernes Forskningsinst | 987p-fimbrie-producerende mikroorganisme, vaccine til immunisering af grise samt fremgangsmaade til fremstilling af vaccinen |
| EP0211543B1 (en) * | 1985-07-31 | 1994-09-14 | The Board Of Trustees Of The Leland Stanford Junior University | Invasive microorganisms |
| FI76484C (fi) | 1986-02-03 | 1988-11-10 | Osmo Norvasto | Kundstol. |
| JPS6399020A (ja) | 1986-06-05 | 1988-04-30 | ベイラ− カレツジ オブ メデイシン | ワクチンとその製法 |
| SU1723116A1 (ru) * | 1988-04-15 | 1992-03-30 | Оренбургский Государственный Медицинский Институт | Штамм бактерий BacILLUS SUвтILIS, используемый дл получени препарата дл профилактики и лечени воспалительных процессов и аллергических заболеваний |
| DE68929405T2 (de) * | 1988-09-06 | 2003-02-06 | Washington University, St. Louis | Orale-immunisierung durch verwendung von transgenen pflanzen |
| SE9401921D0 (sv) * | 1994-06-03 | 1994-06-03 | Sbl Vaccin Ab | A method of cultivating bacteria |
-
1991
- 1991-02-26 SE SE9100556A patent/SE9100556D0/xx unknown
-
1992
- 1992-02-25 RO RO93-01142A patent/RO109819B1/ro unknown
- 1992-02-25 DK DK92906078T patent/DK0573527T3/da active
- 1992-02-25 AT AT92906078T patent/ATE170755T1/de not_active IP Right Cessation
- 1992-02-25 CZ CS931742A patent/CZ281556B6/cs not_active IP Right Cessation
- 1992-02-25 CA CA002104877A patent/CA2104877C/en not_active Expired - Fee Related
- 1992-02-25 HU HU9302410A patent/HU213924B/hu not_active IP Right Cessation
- 1992-02-25 RU RU93053899A patent/RU2127121C1/ru not_active IP Right Cessation
- 1992-02-25 JP JP50610592A patent/JP3169608B2/ja not_active Expired - Fee Related
- 1992-02-25 US US08/108,606 patent/US6558678B1/en not_active Expired - Fee Related
- 1992-02-25 WO PCT/SE1992/000110 patent/WO1992014487A1/en active IP Right Grant
- 1992-02-25 AU AU13308/92A patent/AU663864B2/en not_active Ceased
- 1992-02-25 ES ES92906078T patent/ES2123550T3/es not_active Expired - Lifetime
- 1992-02-25 EP EP92906078A patent/EP0573527B1/en not_active Expired - Lifetime
- 1992-02-25 BR BR9205677A patent/BR9205677A/pt not_active Application Discontinuation
- 1992-02-25 SK SK910-93A patent/SK280919B6/sk unknown
- 1992-02-25 DE DE69226944T patent/DE69226944T2/de not_active Expired - Fee Related
- 1992-02-25 KR KR1019930702564A patent/KR100221452B1/ko not_active Expired - Fee Related
-
1993
- 1993-08-24 OA OA60404A patent/OA09865A/en unknown
- 1993-08-25 NO NO933037A patent/NO307867B1/no unknown
- 1993-08-25 FI FI933728A patent/FI108775B/fi active
- 1993-08-25 BG BG98070A patent/BG61683B1/bg unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA2A | Application withdrawn |
Effective date: 19920128 |
|
| FG2A | Definitive protection |
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