ES2115067T3 - Composiciones y metodos para el tratamiento de enfermedades de autoinmunidad. - Google Patents
Composiciones y metodos para el tratamiento de enfermedades de autoinmunidad.Info
- Publication number
- ES2115067T3 ES2115067T3 ES93916485T ES93916485T ES2115067T3 ES 2115067 T3 ES2115067 T3 ES 2115067T3 ES 93916485 T ES93916485 T ES 93916485T ES 93916485 T ES93916485 T ES 93916485T ES 2115067 T3 ES2115067 T3 ES 2115067T3
- Authority
- ES
- Spain
- Prior art keywords
- methods
- utilities
- compositions
- self
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000203 mixture Substances 0.000 title abstract 2
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- WLJVXDMOQOGPHL-PPJXEINESA-N 2-phenylacetic acid Chemical compound O[14C](=O)CC1=CC=CC=C1 WLJVXDMOQOGPHL-PPJXEINESA-N 0.000 abstract 1
- 208000023275 Autoimmune disease Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 159000000000 sodium salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
LA PRESENTE INVENCION SE REFIERE A METODOS PARA TRATAR ENFERMEDADES AUTOINMUNES ADMINISTRANDO A UN HUESPED AFLIGIDO COMPOSICIONES FARMACEUTICAS QUE CONTIENEN UNA CANTIDAD TERAPEUTICAMENTE EFECTIVA DE UNA COMBINACION DE (A) Y (B) EN UNA RELACION DE PESO QUE VA DE APROXIMADAMENTE 1:1 A APROXIMADAMENTE 1:10 (A:B); DONDE R ES OH, NH2, OW, O H; X ES H, F, C1 BR, I, OH, OW, NO2 O NH2; Y ES H, F, C1, BR, O I; W ES (1) O UN GRUPO ALIFATICO C1-C12; Z ES UN GRUPO AROMATICO O ALIFATICO DE C1-C12; X E Y PUEDEN AMBOS VARIAR DENTRO DEL COMPUESTO; O SALES FARMACEUTICAMENTE ACEPTABLES DE ESTOS. SE DESCRIBE PARTICULARMENTE UNA COMPOSICION QUE COMPRENDE UNA RELACION DE 1 A 4 DE SALES DE SODIO DE FENILACETILGLUTAMINA Y ACIDO FENILACETICO, FORMULADAS TANTO EN FORMA PARENTERAL COMO ORAL CLINICAMENTE UTILES EN EL TRATAMIENTO DE ARTRITIS REUMATOIDE, LUPUS ERYTHEMATOSUS, VASCULITIS, DIABETES MELLITUS INSULINODEPENDIENTE, ESCLEROSIS MULTIPLE.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/898,295 US5646182A (en) | 1992-06-15 | 1992-06-15 | Methods for treating autoimmune diseases |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2115067T3 true ES2115067T3 (es) | 1998-06-16 |
Family
ID=25409238
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES93916485T Expired - Lifetime ES2115067T3 (es) | 1992-06-15 | 1993-06-10 | Composiciones y metodos para el tratamiento de enfermedades de autoinmunidad. |
Country Status (10)
Country | Link |
---|---|
US (1) | US5646182A (es) |
EP (1) | EP0603383B1 (es) |
AT (1) | ATE162714T1 (es) |
AU (1) | AU656484B2 (es) |
DE (1) | DE69316729T2 (es) |
DK (1) | DK0603383T3 (es) |
ES (1) | ES2115067T3 (es) |
GR (1) | GR3026681T3 (es) |
SG (1) | SG81891A1 (es) |
WO (1) | WO1993025201A1 (es) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6127419A (en) * | 1998-11-23 | 2000-10-03 | Burzynski; Stanislaw R. | Phenylacetic acid compositions for treating or preventing atherosclerosis and restenosis |
SE521031C2 (sv) * | 1999-05-05 | 2003-09-23 | Srinivas Uppugunduri | Nya specifika inhibitorer av akut och kronisk inflammation |
EP1642885B1 (en) | 2000-08-29 | 2009-11-11 | Biocon Limited | Use of a pharmaceutical composition containing a para-aminophenyl acetic acid derivative for treating inflammatory conditions of the gastrointestinal tract |
US8048924B2 (en) | 2001-08-29 | 2011-11-01 | Biocon Limited | Methods and compositions employing 4-aminophenylacetic acid compounds |
PL1773767T3 (pl) | 2004-07-07 | 2016-07-29 | Biocon Ltd | Synteza azowo związanych związków immunoregulacyjnych |
EP1890767A2 (en) * | 2005-05-27 | 2008-02-27 | Pfizer Products Inc. | Combination of a cannabinoid-1- receptor-antagonist and a microsomal triglyceride transfer protein inhibitor for treating obesity or mainataining weight loss |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1522212A (en) * | 1975-04-30 | 1978-08-23 | Science Union & Cie | Glutamine derivatives process for their preparation and pharmaceutical compositions containing them |
JPS53113032A (en) * | 1977-03-09 | 1978-10-03 | Mitsubishi Chem Ind Ltd | Immune depresants |
US4438029A (en) * | 1978-01-19 | 1984-03-20 | Research Corporation | Synthetic peptides |
JPS54160740A (en) * | 1978-06-09 | 1979-12-19 | Takeda Chem Ind Ltd | Anti-fibrotic agent |
EP0052296B1 (en) * | 1980-11-12 | 1984-06-27 | Mitsubishi Kasei Corporation | Glutamine derivatives usable for curing immune diseases, methods for their preparation and compositions comprising said derivatives |
US4558057A (en) * | 1981-12-15 | 1985-12-10 | Burzynski Stanislaw R | Purified antineoplaston fractions and methods of treating neoplastic disease |
US5098906A (en) * | 1983-10-31 | 1992-03-24 | Warner-Lambert Company | Purine derivatives |
US4593038A (en) * | 1985-04-03 | 1986-06-03 | Burzynski Stanislaw R | Topical use of 3-phenylacetylamino-2,6-piperidinedione for treatment of skin wrinkles and hyperpigmentation |
US5039704A (en) * | 1985-09-12 | 1991-08-13 | Brigham And Women's Hospital | Method of treating catabolic dysfunction |
ATE54826T1 (de) * | 1985-10-23 | 1990-08-15 | Mulli Kurt Nachf Gmbh | Thymusextraktfraktionen enthaltende pharmazeutische zusammensetzung. |
US4914112A (en) * | 1986-06-03 | 1990-04-03 | Sumitomo Pharmaceuticals Company, Limited | Aminoazole derivatives and their production and use |
US5102883A (en) * | 1989-10-31 | 1992-04-07 | Du Pont Merck Pharmaceutical Company | Pyrimidine biosynthesis inhibitors useful as immunosuppressive agents |
US5108999A (en) * | 1990-02-02 | 1992-04-28 | Syntex (U.S.A.) Inc. | 4-isoxazolecarboxamide derivatives |
US5089508A (en) * | 1990-09-04 | 1992-02-18 | Burzynski Stanislaw R | Methods for treating aids |
US5244922A (en) * | 1990-09-04 | 1993-09-14 | Burzynski Stanislaw R | Methods for treating viral infections |
US5116622A (en) * | 1990-09-12 | 1992-05-26 | Burzynski Stanislaw R | Methods for treating parkinson's disease |
-
1992
- 1992-06-15 US US07/898,295 patent/US5646182A/en not_active Expired - Lifetime
-
1993
- 1993-06-10 AU AU46319/93A patent/AU656484B2/en not_active Ceased
- 1993-06-10 DK DK93916485T patent/DK0603383T3/da active
- 1993-06-10 SG SG9608395A patent/SG81891A1/en unknown
- 1993-06-10 DE DE69316729T patent/DE69316729T2/de not_active Expired - Fee Related
- 1993-06-10 WO PCT/US1993/005555 patent/WO1993025201A1/en active IP Right Grant
- 1993-06-10 EP EP93916485A patent/EP0603383B1/en not_active Expired - Lifetime
- 1993-06-10 ES ES93916485T patent/ES2115067T3/es not_active Expired - Lifetime
- 1993-06-10 AT AT93916485T patent/ATE162714T1/de not_active IP Right Cessation
-
1998
- 1998-04-16 GR GR980400879T patent/GR3026681T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
SG81891A1 (en) | 2001-07-24 |
EP0603383B1 (en) | 1998-01-28 |
EP0603383A1 (en) | 1994-06-29 |
DE69316729T2 (de) | 1998-08-06 |
ATE162714T1 (de) | 1998-02-15 |
EP0603383A4 (en) | 1994-12-21 |
AU4631993A (en) | 1994-01-04 |
WO1993025201A1 (en) | 1993-12-23 |
AU656484B2 (en) | 1995-02-02 |
DE69316729D1 (de) | 1998-03-05 |
GR3026681T3 (en) | 1998-07-31 |
DK0603383T3 (da) | 1998-09-21 |
US5646182A (en) | 1997-07-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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