ES2107124T3 - Procedimiento para inhibir la actividad de endotoxinas. - Google Patents
Procedimiento para inhibir la actividad de endotoxinas.Info
- Publication number
- ES2107124T3 ES2107124T3 ES94300182T ES94300182T ES2107124T3 ES 2107124 T3 ES2107124 T3 ES 2107124T3 ES 94300182 T ES94300182 T ES 94300182T ES 94300182 T ES94300182 T ES 94300182T ES 2107124 T3 ES2107124 T3 ES 2107124T3
- Authority
- ES
- Spain
- Prior art keywords
- activity
- inhibit
- endotoxins
- procedure
- endotoxin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000002158 endotoxin Substances 0.000 title abstract 9
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/579—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving limulus lysate
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
- C07K7/60—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation occurring through the 4-amino group of 2,4-diamino-butanoic acid
- C07K7/62—Polymyxins; Related peptides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
Abstract
MEDIANTE EL CONTACTO DE UN DERIVADO DE PEPTIDO O UNA PROTEINA TENIENDO UNA PROPIEDAD DE FIJACION A LA ENDOTOXINA (ET) PARA INHIBIR LA ACTIVIDAD DE ET, Y AL MENOS UN SURFACTANTE CON UNA MUESTRA CONTENIENDO ET, LA ACTIVIDAD DE ET PUEDE INHIBIRSE, E INCLUSO CUANDO UNA SUSTANCIA ANALOGA ET, TENIENDO ACTIVIDAD ET ESTE PRESENTE EN LA MUESTRA ASI TRATADA, PUEDE MEDIRSE SIN INFLUENCIA DE ET.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2615993 | 1993-01-21 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2107124T3 true ES2107124T3 (es) | 1997-11-16 |
Family
ID=12185777
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES94300182T Expired - Lifetime ES2107124T3 (es) | 1993-01-21 | 1994-01-11 | Procedimiento para inhibir la actividad de endotoxinas. |
Country Status (7)
Country | Link |
---|---|
US (3) | US5750500A (es) |
EP (1) | EP0608982B1 (es) |
KR (1) | KR100255993B1 (es) |
CN (2) | CN1120370C (es) |
CA (1) | CA2112776C (es) |
DE (1) | DE69405594T2 (es) |
ES (1) | ES2107124T3 (es) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2112776C (en) * | 1993-01-21 | 2002-11-12 | Masakazu Tsuchiya | Process for inhibiting activity of endotoxin |
CN1418256A (zh) * | 2000-03-24 | 2003-05-14 | 雀巢制品公司 | 来自丝状真菌的β葡聚糖 |
JPWO2002101836A1 (ja) * | 2001-06-12 | 2004-09-30 | 株式会社日立製作所 | 半導体装置およびその製造方法 |
MXPA05005338A (es) * | 2002-11-18 | 2005-12-14 | Vicuron Pharm Inc | Metodos para administrar dalbavancin para el tratamiento de infecciones bacterianas. |
WO2005010207A2 (en) * | 2003-03-17 | 2005-02-03 | Charles River Laboratories, Inc. | Methods and compositions for the detection of microbial contaminants |
US20060004185A1 (en) * | 2004-07-01 | 2006-01-05 | Leese Richard A | Peptide antibiotics and peptide intermediates for their prepartion |
WO2007078268A2 (en) | 2004-12-02 | 2007-07-12 | Charles River Laboratories, Inc. | Methods and compositions for the detection and/or quantification of gram positive bacterial contaminants |
JP5096166B2 (ja) * | 2005-01-13 | 2012-12-12 | チャールズ リバー ラボラトリーズ, インコーポレイテッド | 生体サンプル中の微生物を分類する方法 |
WO2009137244A1 (en) * | 2008-04-15 | 2009-11-12 | Charles River Laboratories, Inc. | Cartridge and method for sample analysis |
AR074874A1 (es) | 2008-12-23 | 2011-02-16 | Biosource Pharm Inc | Composiciones antibioticas para el tratamiento de infecciones gram negativas. metodo. uso. compuesto. |
WO2010151751A2 (en) * | 2009-06-26 | 2010-12-29 | Charles River Laboratories, Inc. | Heat-treated limulus amebocyte lysates |
US8415307B1 (en) | 2010-06-23 | 2013-04-09 | Biosource Pharm, Inc. | Antibiotic compositions for the treatment of gram negative infections |
US20130078665A1 (en) * | 2012-07-18 | 2013-03-28 | Deepika Bodapati | Test strip, a test kit and a method for detection of endotoxin in food |
CN103592442B (zh) * | 2013-10-29 | 2016-01-20 | 王明丽 | 一种检测重组猪干扰素α1冻干粉针剂中细菌内毒素含量的方法 |
CN108387739A (zh) * | 2018-01-23 | 2018-08-10 | 福州启新生物技术有限公司 | 一种特异性检测血清中真菌的试剂及其制备方法 |
CN109142760B (zh) * | 2018-07-04 | 2021-02-02 | 中国农业大学 | 一种快速准确检测饲料中粘杆菌素的试剂盒 |
Family Cites Families (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5648897A (en) * | 1979-09-25 | 1981-05-02 | Nitsusui Seiyaku Kk | Selective isolation medium for cholera bacillus |
US4276050A (en) * | 1980-01-10 | 1981-06-30 | Abbott Laboratories | Method for systemic endotoxin detection |
US4322217A (en) * | 1980-06-27 | 1982-03-30 | Mallinckrodt, Inc. | Process for preparing Limulus lysate |
JPS5813519A (ja) * | 1981-07-16 | 1983-01-26 | Seikagaku Kogyo Co Ltd | エンドトキシン吸着材及びそれを用いるエンドトキシンの除去方法 |
JPS5967210A (ja) * | 1982-10-09 | 1984-04-16 | Nissan Chem Ind Ltd | 線虫防除剤 |
JPS60184100A (ja) * | 1984-03-02 | 1985-09-19 | Toray Ind Inc | ポリミキシンの固定化方法 |
ATE188777T1 (de) * | 1986-12-03 | 2000-01-15 | Wako Pure Chem Ind Ltd | Verfahren zum sammeln von insekten- körperflussigkeiten |
US4803314A (en) * | 1986-12-22 | 1989-02-07 | Carlingswitch, Inc. | Momentary rotary switch |
DK255887D0 (da) * | 1987-05-20 | 1987-05-20 | Claus Koch | Immunoassay |
CA1337781C (en) * | 1987-08-21 | 1995-12-19 | Takanori Nakamura | Polypeptide from horseshoe crab exhibiting affinity for lipopolysaccharide and method of preparation |
US4808314A (en) * | 1987-09-18 | 1989-02-28 | Scripps Clinic And Research Foundation | Method for reducing bacterial endotoxin contamination in solutions of macromolecules |
JPH0715474B2 (ja) * | 1988-02-27 | 1995-02-22 | 和光純薬工業株式会社 | エンドトキシンの測定法 |
JPH0711523B2 (ja) * | 1988-03-16 | 1995-02-08 | 和光純薬工業株式会社 | 試薬の調製方法 |
US5594113A (en) * | 1988-06-23 | 1997-01-14 | Associates Of Cape Cod, Inc. | Endotoxin binding and neutralizing protein and uses thereof |
JP2688773B2 (ja) * | 1988-11-24 | 1997-12-10 | 和光純薬工業株式会社 | エンドトキシンの不活化方法 |
JP2701916B2 (ja) * | 1989-02-08 | 1998-01-21 | マルハ株式会社 | β―グルカンに対する特異性の高いアメボサイト・ライセート及びその調製方法 |
US5234912A (en) * | 1989-02-14 | 1993-08-10 | Incyte Pharmaceuticals, Inc. | Pharmaceutical compositions comprising recombinant BPI proteins and a lipid carrier and uses thereof |
US5177059A (en) * | 1989-11-15 | 1993-01-05 | Sandoz Ltd. | Polymyxin B conjugates |
JP3085310B2 (ja) * | 1990-04-26 | 2000-09-04 | 日本バイリーン株式会社 | 微生物除去材 |
CA2037727A1 (en) * | 1991-03-07 | 1992-09-08 | Burton W. Blais | Removing lps pyrogen from aqueous solution |
JP2944709B2 (ja) * | 1990-06-21 | 1999-09-06 | 生化学工業株式会社 | (1→3)―β―D―グルカンの測定剤 |
US5198339A (en) * | 1990-07-13 | 1993-03-30 | Board Of Regents, The University Of Texas System | Method for detection of gram-negative bacterial lipopolysaccharides in biological fluids |
ES2104855T3 (es) * | 1991-12-24 | 1997-10-16 | Wako Pure Chem Ind Ltd | Procedimiento para extraer endotoxinas. |
EP0549102B1 (en) * | 1991-12-25 | 1996-07-03 | Maruha Corporation | Beta-glucans detection reagents and methods of detecting beta-glucans |
US5552294A (en) * | 1992-10-20 | 1996-09-03 | Children's Medical Center Corporation | Rapid detection of virulence-associated factors |
CA2112776C (en) * | 1993-01-21 | 2002-11-12 | Masakazu Tsuchiya | Process for inhibiting activity of endotoxin |
-
1994
- 1994-01-04 CA CA002112776A patent/CA2112776C/en not_active Expired - Fee Related
- 1994-01-11 DE DE69405594T patent/DE69405594T2/de not_active Expired - Fee Related
- 1994-01-11 ES ES94300182T patent/ES2107124T3/es not_active Expired - Lifetime
- 1994-01-11 EP EP94300182A patent/EP0608982B1/en not_active Expired - Lifetime
- 1994-01-19 KR KR1019940000977A patent/KR100255993B1/ko not_active IP Right Cessation
- 1994-01-20 CN CN94100515A patent/CN1120370C/zh not_active Expired - Fee Related
-
1995
- 1995-05-31 US US08/455,563 patent/US5750500A/en not_active Expired - Fee Related
- 1995-05-31 US US08/455,531 patent/US5622833A/en not_active Expired - Fee Related
- 1995-05-31 US US08/454,866 patent/US5616557A/en not_active Expired - Fee Related
-
2002
- 2002-01-29 CN CN02103211A patent/CN1379248A/zh active Pending
Also Published As
Publication number | Publication date |
---|---|
DE69405594D1 (de) | 1997-10-23 |
EP0608982B1 (en) | 1997-09-17 |
CN1120370C (zh) | 2003-09-03 |
KR100255993B1 (ko) | 2000-05-01 |
CA2112776C (en) | 2002-11-12 |
CN1379248A (zh) | 2002-11-13 |
EP0608982A3 (en) | 1995-04-19 |
US5750500A (en) | 1998-05-12 |
US5616557A (en) | 1997-04-01 |
CN1109598A (zh) | 1995-10-04 |
EP0608982A2 (en) | 1994-08-03 |
DE69405594T2 (de) | 1998-03-19 |
US5622833A (en) | 1997-04-22 |
KR940018097A (ko) | 1994-08-16 |
CA2112776A1 (en) | 1994-07-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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