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ES2088550T3 - Recubrimientos que ocultan el sabor para preparar comprimidos farmaceuticos masticables. - Google Patents

Recubrimientos que ocultan el sabor para preparar comprimidos farmaceuticos masticables.

Info

Publication number
ES2088550T3
ES2088550T3 ES92309413T ES92309413T ES2088550T3 ES 2088550 T3 ES2088550 T3 ES 2088550T3 ES 92309413 T ES92309413 T ES 92309413T ES 92309413 T ES92309413 T ES 92309413T ES 2088550 T3 ES2088550 T3 ES 2088550T3
Authority
ES
Spain
Prior art keywords
flavor
granules
hide
coatings
pharmaceutical tablets
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92309413T
Other languages
English (en)
Inventor
Edward J Roche
Eleanor M Freeman
Susan M Papile
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kenvue Brands LLC
Original Assignee
McNeil PPC Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by McNeil PPC Inc filed Critical McNeil PPC Inc
Application granted granted Critical
Publication of ES2088550T3 publication Critical patent/ES2088550T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)

Abstract

LAS TABLETAS MASTICABLES DE MEDICAMENTO SE HACEN A PARTIR DE GRANULOS REVESTIDOS DE UN MEDICAMENTO EN EL QUE LOS GRANULOS SE FORMAN A PARTIR DE UNA MEZCLA DE GRANULACION DE: EL MEDICAMENTO, POR EJEMPLO FAMOTIDINA; AMALGAMADOR, POR EJEMPLO HPMC; Y UN PORTADOR, POR EJEMPLO LACTOSA; Y LOS GRANULOS SE RECUBREN CON ACETATO DE CELULOSA, BUTIRATO DE ACETATO DE CELULOSA O UNA COMBINACION DE LOS MISMOS Y CELULOSA DE HIDROXIPROPIL. TAMBIEN SE PRESENTA UN PROCESO PARA FABRICAR DICHAS TABLETAS Y UN METODO PARA SUMINISTRAR UN ENMASCARAMIENTO DEL SABOR A MEDICAMENTOS UTILIZANDO DICHOS GRANULOS RECUBIERTOS.
ES92309413T 1991-10-15 1992-10-15 Recubrimientos que ocultan el sabor para preparar comprimidos farmaceuticos masticables. Expired - Lifetime ES2088550T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US77787291A 1991-10-15 1991-10-15

Publications (1)

Publication Number Publication Date
ES2088550T3 true ES2088550T3 (es) 1996-08-16

Family

ID=25111568

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92309413T Expired - Lifetime ES2088550T3 (es) 1991-10-15 1992-10-15 Recubrimientos que ocultan el sabor para preparar comprimidos farmaceuticos masticables.

Country Status (5)

Country Link
EP (1) EP0538034B1 (es)
CA (1) CA2079934C (es)
DE (1) DE69209764T2 (es)
ES (1) ES2088550T3 (es)
GR (1) GR1002100B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9221414D0 (en) * 1992-10-13 1992-11-25 Glaxo Group Ltd Pharmaceutical compositions
US5529783A (en) * 1994-12-19 1996-06-25 Mcneil-Ppc, Inc. Rotor granulation and coating of acetaminophen, pseudoephedrine, chlorpheniramine, and, optionally dextromethorphan
US8071128B2 (en) 1996-06-14 2011-12-06 Kyowa Hakko Kirin Co., Ltd. Intrabuccally rapidly disintegrating tablet and a production method of the tablets
US9358214B2 (en) 2001-10-04 2016-06-07 Adare Pharmaceuticals, Inc. Timed, sustained release systems for propranolol
US8367111B2 (en) 2002-12-31 2013-02-05 Aptalis Pharmatech, Inc. Extended release dosage forms of propranolol hydrochloride
US8545881B2 (en) 2004-04-19 2013-10-01 Eurand Pharmaceuticals, Ltd. Orally disintegrating tablets and methods of manufacture
US8747895B2 (en) 2004-09-13 2014-06-10 Aptalis Pharmatech, Inc. Orally disintegrating tablets of atomoxetine
US9884014B2 (en) 2004-10-12 2018-02-06 Adare Pharmaceuticals, Inc. Taste-masked pharmaceutical compositions
EP1802285B1 (en) 2004-10-21 2013-02-27 Aptalis Pharmatech, Inc. Taste-masked pharmaceutical compositions with gastrosoluble pore-formers
US9161918B2 (en) 2005-05-02 2015-10-20 Adare Pharmaceuticals, Inc. Timed, pulsatile release systems
EP2506836B1 (en) 2009-12-02 2018-02-14 Adare Pharmaceuticals S.R.L. Fexofenadine microcapsules and compositions containing them
WO2017091166A1 (en) 2015-11-26 2017-06-01 Pharmacti̇ve İlaç San. Ve Ti̇c. A.Ş. Stable pharmaceutical compositions and process for their preparation
WO2022200897A1 (en) 2021-03-24 2022-09-29 Johnson & Johnson Consumer Inc. A pharmaceutical composition comprising famotidine

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4801461A (en) * 1987-01-28 1989-01-31 Alza Corporation Pseudoephedrine dosage form
JPH0774166B2 (ja) * 1987-02-06 1995-08-09 信越化学工業株式会社 徐放性被覆薬剤の製造方法
NZ234587A (en) * 1989-08-04 1991-11-26 Mcneil Ppc Inc A chewable pharmaceutical tablet of compressed coated granules
US5075114A (en) * 1990-05-23 1991-12-24 Mcneil-Ppc, Inc. Taste masking and sustained release coatings for pharmaceuticals
CA2052679C (en) * 1990-08-30 1997-12-02 Edward J. Roche Rotogranulations and taste masking coatings for preparation of chewable pharmaceutical tablets

Also Published As

Publication number Publication date
EP0538034B1 (en) 1996-04-10
DE69209764T2 (de) 1996-09-05
CA2079934A1 (en) 1993-04-16
EP0538034A1 (en) 1993-04-21
GR1002100B (en) 1995-12-29
CA2079934C (en) 2002-09-03
DE69209764D1 (de) 1996-05-15
GR920100438A (el) 1993-06-30

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