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ES2088371A1 - Process for the production of type 1 bovine herpesvirus gE glycoprotein antigens in recombinant form and its use in serological differentiation between infected animals and vaccinated animals - Google Patents

Process for the production of type 1 bovine herpesvirus gE glycoprotein antigens in recombinant form and its use in serological differentiation between infected animals and vaccinated animals

Info

Publication number
ES2088371A1
ES2088371A1 ES09500180A ES9500180A ES2088371A1 ES 2088371 A1 ES2088371 A1 ES 2088371A1 ES 09500180 A ES09500180 A ES 09500180A ES 9500180 A ES9500180 A ES 9500180A ES 2088371 A1 ES2088371 A1 ES 2088371A1
Authority
ES
Spain
Prior art keywords
animals
type
production
bovine herpesvirus
recombinant form
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES09500180A
Other languages
Spanish (es)
Other versions
ES2088371B1 (en
Inventor
Xavier Rebordosa
Jaume Pinol
Josep-Antoni Perez-Pons
Jordi Naval
Jorge Lloberas
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratorios Hipra SA
Original Assignee
Laboratorios Hipra SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorios Hipra SA filed Critical Laboratorios Hipra SA
Priority to ES9500180A priority Critical patent/ES2088371B1/en
Publication of ES2088371A1 publication Critical patent/ES2088371A1/en
Application granted granted Critical
Publication of ES2088371B1 publication Critical patent/ES2088371B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Process used for the production of antigens corresponding to type 1 bovine herpesvirus gE glycoprotein in recombinant form and their use in serological differentiation between infected animals and vaccinated animals. The process comprises selection of those segments of the gene of the type 1 bovine herpesvirus gE glycoprotein which can be expressed in a prokaryotic vector, the expression of these sequences and use of the resulting polypeptides. The recombinant protein produced can be used for the generation of antibodies, the diagnosis of bovine infectious rhinotracheitis and serological differentiation between infected animals and vaccinated animals.
ES9500180A 1995-02-01 1995-02-01 PROCEDURE FOR THE RECOMBINANT PRODUCTION OF ANTIGENS OF THE GLYCOPROTEIN GE OF BOVINE HERPESVIRUS TYPE 1 AND ITS USE IN THE SEROLOGICAL DIFFERENTIATION BETWEEN INFECTED ANIMALS AND VACCINATED ANIMALS. Expired - Fee Related ES2088371B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES9500180A ES2088371B1 (en) 1995-02-01 1995-02-01 PROCEDURE FOR THE RECOMBINANT PRODUCTION OF ANTIGENS OF THE GLYCOPROTEIN GE OF BOVINE HERPESVIRUS TYPE 1 AND ITS USE IN THE SEROLOGICAL DIFFERENTIATION BETWEEN INFECTED ANIMALS AND VACCINATED ANIMALS.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES9500180A ES2088371B1 (en) 1995-02-01 1995-02-01 PROCEDURE FOR THE RECOMBINANT PRODUCTION OF ANTIGENS OF THE GLYCOPROTEIN GE OF BOVINE HERPESVIRUS TYPE 1 AND ITS USE IN THE SEROLOGICAL DIFFERENTIATION BETWEEN INFECTED ANIMALS AND VACCINATED ANIMALS.

Publications (2)

Publication Number Publication Date
ES2088371A1 true ES2088371A1 (en) 1996-08-01
ES2088371B1 ES2088371B1 (en) 1997-04-16

Family

ID=8289320

Family Applications (1)

Application Number Title Priority Date Filing Date
ES9500180A Expired - Fee Related ES2088371B1 (en) 1995-02-01 1995-02-01 PROCEDURE FOR THE RECOMBINANT PRODUCTION OF ANTIGENS OF THE GLYCOPROTEIN GE OF BOVINE HERPESVIRUS TYPE 1 AND ITS USE IN THE SEROLOGICAL DIFFERENTIATION BETWEEN INFECTED ANIMALS AND VACCINATED ANIMALS.

Country Status (1)

Country Link
ES (1) ES2088371B1 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992021751A1 (en) * 1991-06-07 1992-12-10 Stichting Centraal Diergeneeskundig Instituut Bovine herpesvirus type 1 deletion mutants, vaccines based thereon, diagnostic kits for detection of bovine herpesvirus type 1
WO1993011792A1 (en) * 1991-12-11 1993-06-24 University Of Saskatchewan Recombinant bovine herpesvirus type 1 polypeptides and vaccines

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992021751A1 (en) * 1991-06-07 1992-12-10 Stichting Centraal Diergeneeskundig Instituut Bovine herpesvirus type 1 deletion mutants, vaccines based thereon, diagnostic kits for detection of bovine herpesvirus type 1
WO1993011792A1 (en) * 1991-12-11 1993-06-24 University Of Saskatchewan Recombinant bovine herpesvirus type 1 polypeptides and vaccines

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DRUNEN LITTEL H. et al. "Expression of Bovine Herpesvirus 1 Glycoprotein gIV by Recombinant Baculovirus and Analysis of its Immunogenic Properties". Journal of Virology. Enero 1991. Pßginas 263-271 *
FITZPATRICK D.R. et al. "Expression of Bovine Herpesvirus 1 Glycoproteins gI and gIII in Transfected Murine Cells". Journal of Virology. Noviembre 1988. Pßginas 4239-4248 *
REBORDOSA X. et al. "Mapping, cloning and sequencing of a glycoprotein - encoding gene from bovine herpesvirus type 1 homologous to the gE gene from HSV-1". Gene. 1994. Vol. 149, pßginas 203-209 *

Also Published As

Publication number Publication date
ES2088371B1 (en) 1997-04-16

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