ES2085346T3 - Deteccion de componentes de la membrana basal como diagnostico del cancer y de otras enfermedades. - Google Patents
Deteccion de componentes de la membrana basal como diagnostico del cancer y de otras enfermedades.Info
- Publication number
- ES2085346T3 ES2085346T3 ES90901339T ES90901339T ES2085346T3 ES 2085346 T3 ES2085346 T3 ES 2085346T3 ES 90901339 T ES90901339 T ES 90901339T ES 90901339 T ES90901339 T ES 90901339T ES 2085346 T3 ES2085346 T3 ES 2085346T3
- Authority
- ES
- Spain
- Prior art keywords
- diagnosis
- diseases
- detection
- components
- fragments
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000012528 membrane Substances 0.000 title abstract 4
- 238000003745 diagnosis Methods 0.000 title abstract 3
- 238000001514 detection method Methods 0.000 title abstract 2
- 201000010099 disease Diseases 0.000 title abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 2
- 206010028980 Neoplasm Diseases 0.000 title 1
- 201000011510 cancer Diseases 0.000 title 1
- 239000012634 fragment Substances 0.000 abstract 3
- 239000007788 liquid Substances 0.000 abstract 3
- 102000008186 Collagen Human genes 0.000 abstract 1
- 108010035532 Collagen Proteins 0.000 abstract 1
- 210000004556 brain Anatomy 0.000 abstract 1
- 229920001436 collagen Polymers 0.000 abstract 1
- 208000006454 hepatitis Diseases 0.000 abstract 1
- 231100000283 hepatitis Toxicity 0.000 abstract 1
- 230000001900 immune effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000011197 physicochemical method Methods 0.000 abstract 1
- 210000002966 serum Anatomy 0.000 abstract 1
- 210000002700 urine Anatomy 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57415—Specifically defined cancers of breast
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57423—Specifically defined cancers of lung
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/5743—Specifically defined cancers of skin, e.g. melanoma
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57438—Specifically defined cancers of liver, pancreas or kidney
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
- G01N33/57488—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds identifable in body fluids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Communicable Diseases (AREA)
- Gastroenterology & Hepatology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
SE EXPONEN LOS METODOS PARA EL DIAGNOSTICO DE ENFERMEDADES QUE DAN COMO RESULTADO LA LIBERACION DE FRAGMENTOS DE UNA MEMBRANA BASE, QUE INCLUYEN LOS FRAGMENTOS, LAS MOLECULAS INTACTAS Y/O LOS COMPLEJOS DE COMPONENTES DE MEMBRANA BASE. LA DETECCION DE LOS FRAGMENTOS DE LA MEMBRANA BASE, DE LAS MOLECULAS INTACTAS Y/O LOS COMPLEJOS EN UN LIQUIDO BIOLOGICO MEDIANTE LOS METODOS INMUNOLOGICOS Y FISICOQUIMICOS DE LA INVENCION ACTUAL PERMITEN EL DIAGNOSTICO DE UNA VARIEDAD DE ENFERMEDADES, INCLUYENDO EL CANCER, LAS ENFERMEDADES DEGENERATIVAS DEL COLAGENO Y LA HEPATITIS. LIQUIDOS BIOLOGICOS IDONEOS QUE INCLUYEN LA ORINA, EL SUERO, EL LIQUIDO SINOVIAL Y EL CEREBROESPINAL.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US28339788A | 1988-12-12 | 1988-12-12 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2085346T3 true ES2085346T3 (es) | 1996-06-01 |
Family
ID=23085870
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES90901339T Expired - Lifetime ES2085346T3 (es) | 1988-12-12 | 1989-12-11 | Deteccion de componentes de la membrana basal como diagnostico del cancer y de otras enfermedades. |
Country Status (7)
Country | Link |
---|---|
EP (2) | EP0664453A1 (es) |
JP (1) | JPH04502363A (es) |
AU (1) | AU4845390A (es) |
CA (1) | CA2005190A1 (es) |
DE (1) | DE68926245T2 (es) |
ES (1) | ES2085346T3 (es) |
WO (1) | WO1990007116A1 (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5512657A (en) * | 1988-12-12 | 1996-04-30 | Bainbridge Sciences, Inc. | Detection of complexes which include basement membrane components as diagnostic of cancer and other diseases |
AU665764B2 (en) * | 1991-05-29 | 1996-01-18 | Baxter International Inc. | Methods and compositions for the prevention, diagnosis, and treatment of inflammatory serosal disease and related conditions |
AU667500B2 (en) * | 1991-12-13 | 1996-03-28 | Bard Diagnostic Sciences, Inc. | Agglutination assays and kits employing colloidal dyes |
EP0710362B1 (en) * | 1993-07-23 | 1998-11-04 | Bard Diagnostic Sciences, Inc. | Methods for determining the invasiveness of a bladder tumor |
JPH08100000A (ja) * | 1994-09-30 | 1996-04-16 | Morinaga & Co Ltd | ヒトiv型コラーゲンに対する抗体及びその利用 |
AU3728595A (en) * | 1994-10-18 | 1996-05-06 | Amdl, Inc. | Antibodies against an extracellular matrix complex and their use in the detection of cancer |
JP5754844B2 (ja) * | 2010-03-09 | 2015-07-29 | 国立大学法人 東京大学 | 泌尿器科がんの検査方法及び検査用キット |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2923583A1 (de) * | 1979-06-11 | 1980-12-18 | Max Planck Gesellschaft | Verfahren zur immunologischen bestimmung von basalmembranmaterial und hierfuer geeignete neue basalmembranfragmente |
JPS59212768A (ja) * | 1983-05-18 | 1984-12-01 | Green Cross Corp:The | 人胎盤由来基底膜関連蛋白質bmap測定用試薬 |
DE3410049A1 (de) * | 1984-03-19 | 1985-09-19 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen | Verfahren zur gewinnung der globulaeren domaene von basalmembrankollagen und immunologische bestimmung von basalmembranmaterial und autoantikoerpern |
DE3511199A1 (de) * | 1985-03-28 | 1986-10-02 | Hoechst Ag, 6230 Frankfurt | Verfahren zur immunologischen bestimmung von heparansulfat-proteoglykan, verfahren zur herstellung bzw. reinigung von dafuer geeignetem heparansulfat-proteoglykan aus basalmembran-haltigen geweben |
FR2606034B1 (fr) * | 1986-10-31 | 1989-06-02 | Cird | Nouvelle proteine de surface des cellules basales de l'epiderme, anticorps capables de reconnaitre cette proteine, et leur utilisation, et lignees cellulaires hybrides capables de secreter de tels anticorps |
SE461616B (sv) * | 1987-05-08 | 1990-03-05 | Biocarb Ab | Foerfarande och testsats vid diagnos av iga nefropati med bestaemning av fibronektin-iga-komplex |
-
1989
- 1989-12-11 CA CA 2005190 patent/CA2005190A1/en not_active Abandoned
- 1989-12-11 ES ES90901339T patent/ES2085346T3/es not_active Expired - Lifetime
- 1989-12-11 AU AU48453/90A patent/AU4845390A/en not_active Abandoned
- 1989-12-11 DE DE68926245T patent/DE68926245T2/de not_active Expired - Fee Related
- 1989-12-11 EP EP95105056A patent/EP0664453A1/en not_active Withdrawn
- 1989-12-11 WO PCT/US1989/005534 patent/WO1990007116A1/en active IP Right Grant
- 1989-12-11 JP JP2502222A patent/JPH04502363A/ja active Pending
- 1989-12-11 EP EP90901339A patent/EP0447490B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
DE68926245D1 (de) | 1996-05-15 |
AU4845390A (en) | 1990-07-10 |
WO1990007116A1 (en) | 1990-06-28 |
EP0447490A1 (en) | 1991-09-25 |
EP0664453A1 (en) | 1995-07-26 |
DE68926245T2 (de) | 1996-08-22 |
EP0447490B1 (en) | 1996-04-10 |
JPH04502363A (ja) | 1992-04-23 |
CA2005190A1 (en) | 1990-06-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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