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ES2085198B1 - Un procedimiento para la preparacion de una proteina adherente a celulas macroscopicamente orientada y porosa. - Google Patents

Un procedimiento para la preparacion de una proteina adherente a celulas macroscopicamente orientada y porosa.

Info

Publication number
ES2085198B1
ES2085198B1 ES09250038A ES9250038A ES2085198B1 ES 2085198 B1 ES2085198 B1 ES 2085198B1 ES 09250038 A ES09250038 A ES 09250038A ES 9250038 A ES9250038 A ES 9250038A ES 2085198 B1 ES2085198 B1 ES 2085198B1
Authority
ES
Spain
Prior art keywords
procedure
preparation
macroscopically oriented
porous cells
protein adherent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
ES09250038A
Other languages
English (en)
Other versions
ES2085198A1 (es
Inventor
Robert Brown
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University College London
Original Assignee
University College London
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University College London filed Critical University College London
Publication of ES2085198A1 publication Critical patent/ES2085198A1/es
Application granted granted Critical
Publication of ES2085198B1 publication Critical patent/ES2085198B1/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/32—Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/252—Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412—Tissue-regenerating or healing or proliferative agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Materials Engineering (AREA)
  • Materials For Medical Uses (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Manufacture Of Macromolecular Shaped Articles (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Manufacture Of Motors, Generators (AREA)
  • Winding Of Webs (AREA)

Abstract

UN PROCEDIMIENTO PARA LA PREPARACION DE UNA PROTEINA ADHERENTE A CELULAS MACROSCOPICAMENTE ORIENTADA Y POROSA. COMPRENDE: (A) PREPARAR UNA SOLUCION DE PROTEINA EN UN DISOLVENTE ACUOSO; (B) ELIMINAR EL DISOLVENTE DE LA SOLUCION POR EVAPORACION, FILTRACION, CONCENTRACION O POR AGREGACION O PRECIPITACION DE LA PROTEINA; (C) RECOGER, LAVAR Y SECAR EL PRECIPITADO DE PROTEINA O AGREGADO YA ORIENTADO Y, OPCIONALMENTE, ESTABILIZAR QUIMICAMENTE LA PROTEINA RESULTANTE. LA PROTEINA ES UTIL EN EL TRATAMIENTO DE LAS HERIDAS Y PUEDE EMPLEARSE PARA PROMOVER Y DIRIGIR LA CURACION DE LAS HERIDAS. LA FORMULACION DEPOT ES UTIL PARA EL TRATAMIENTO DE HERIDAS EN SERES HUMANOS Y ANIMALES.
ES09250038A 1991-01-18 1992-01-17 Un procedimiento para la preparacion de una proteina adherente a celulas macroscopicamente orientada y porosa. Expired - Fee Related ES2085198B1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB919101191A GB9101191D0 (en) 1991-01-18 1991-01-18 Wound treatment

Publications (2)

Publication Number Publication Date
ES2085198A1 ES2085198A1 (es) 1996-05-16
ES2085198B1 true ES2085198B1 (es) 1996-12-01

Family

ID=10688704

Family Applications (1)

Application Number Title Priority Date Filing Date
ES09250038A Expired - Fee Related ES2085198B1 (es) 1991-01-18 1992-01-17 Un procedimiento para la preparacion de una proteina adherente a celulas macroscopicamente orientada y porosa.

Country Status (11)

Country Link
EP (1) EP0567508B1 (es)
JP (1) JPH06504926A (es)
AT (1) ATE202787T1 (es)
AU (1) AU662314B2 (es)
CH (1) CH684271A5 (es)
DE (1) DE69231916T2 (es)
DK (1) DK0567508T3 (es)
ES (1) ES2085198B1 (es)
GB (1) GB9101191D0 (es)
GR (1) GR3036775T3 (es)
WO (1) WO1992013003A1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9315810D0 (en) * 1993-07-30 1993-09-15 Univ London Stabilised materials
DE4328190A1 (de) * 1993-08-23 1995-03-02 Beiersdorf Ag Wundversorgungsartikel mit selektivem Absorptionsvermögen
US7112320B1 (en) 1995-06-07 2006-09-26 Andre Beaulieu Solid wound healing formulations containing fibronectin
US5877149A (en) 1995-06-07 1999-03-02 Beaulieu; Andre Deepithelialized skin diffusion cell system
US5641483A (en) * 1995-06-07 1997-06-24 Beaulieu; Andre Wound healing formulations containing human plasma fibronectin
GB9724879D0 (en) * 1997-11-26 1998-01-21 Univ London Process for the production of protein and products thereof
GB9826658D0 (en) * 1998-12-03 1999-01-27 Univ London Tissue repair
DK1218027T3 (da) * 1999-09-15 2010-05-10 Euclid Systems Corp Sammensætning til stabilisering af hornhindevæv under eller efter bæring af ortokeratologiske linser
GB0031089D0 (en) * 2000-12-20 2001-01-31 Univ London Tissue growth method and apparatus
AU2002366585A1 (en) * 2001-12-13 2003-06-23 Andrew Stevens Von willebrand factor-coated biocompatible implants

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4925924A (en) * 1984-03-27 1990-05-15 University Of Medicine And Dentistry Of New Jersey Biocompatible synthetic and collagen compositions having a dual-type porosity for treatment of wounds and pressure ulcers and therapeutic methods thereof
US4973466A (en) * 1988-06-21 1990-11-27 Chiron Ophthalmics, Inc. Wound-healing dressings and methods
GB9101183D0 (en) * 1991-01-18 1991-02-27 Univ London Depot formulations
JP2948708B2 (ja) * 1991-11-27 1999-09-13 ニューヨーク・ブラッド・センター・インコーポレーテッド フィブロネクチン含有点眼液

Also Published As

Publication number Publication date
ES2085198A1 (es) 1996-05-16
ATE202787T1 (de) 2001-07-15
EP0567508A1 (en) 1993-11-03
EP0567508B1 (en) 2001-07-04
AU1172292A (en) 1992-08-27
JPH06504926A (ja) 1994-06-09
CH684271A5 (de) 1994-08-15
DE69231916D1 (de) 2001-08-09
DK0567508T3 (da) 2001-10-22
GB9101191D0 (en) 1991-02-27
AU662314B2 (en) 1995-08-31
WO1992013003A1 (en) 1992-08-06
DE69231916T2 (de) 2002-04-11
GR3036775T3 (en) 2002-01-31

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