ES2078339T3 - Composiciones a base de proantocianidoles; su aplicacion farmacologica. - Google Patents
Composiciones a base de proantocianidoles; su aplicacion farmacologica.Info
- Publication number
- ES2078339T3 ES2078339T3 ES90905558T ES90905558T ES2078339T3 ES 2078339 T3 ES2078339 T3 ES 2078339T3 ES 90905558 T ES90905558 T ES 90905558T ES 90905558 T ES90905558 T ES 90905558T ES 2078339 T3 ES2078339 T3 ES 2078339T3
- Authority
- ES
- Spain
- Prior art keywords
- composition
- proantocianidoles
- compositions based
- relates
- sugars
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000203 mixture Substances 0.000 title abstract 4
- 230000000144 pharmacologic effect Effects 0.000 title 1
- 235000000346 sugar Nutrition 0.000 abstract 2
- 150000008163 sugars Chemical class 0.000 abstract 2
- 229930091371 Fructose Natural products 0.000 abstract 1
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 abstract 1
- 239000005715 Fructose Substances 0.000 abstract 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
- 229920002472 Starch Polymers 0.000 abstract 1
- 229930006000 Sucrose Natural products 0.000 abstract 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 abstract 1
- 229920002253 Tannate Polymers 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 abstract 1
- 239000001913 cellulose Substances 0.000 abstract 1
- 229920002678 cellulose Polymers 0.000 abstract 1
- 235000013681 dietary sucrose Nutrition 0.000 abstract 1
- 239000000686 essence Substances 0.000 abstract 1
- 239000008103 glucose Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229920005989 resin Polymers 0.000 abstract 1
- 239000011347 resin Substances 0.000 abstract 1
- -1 starch Chemical class 0.000 abstract 1
- 239000008107 starch Substances 0.000 abstract 1
- 235000019698 starch Nutrition 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 229960004793 sucrose Drugs 0.000 abstract 1
- 235000013311 vegetables Nutrition 0.000 abstract 1
- 239000000341 volatile oil Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/60—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2
- C07D311/62—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2 with oxygen atoms directly attached in position 3, e.g. anthocyanidins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
LA INVENCION SE REFIERE UNA COMPOSICION A BASE DE PROANTOCIAMIDOLES, EN PARTICULAR DE ORIGEN VEGETAL, CARACTERIZADO POR UNA PROPORCION PONDERAL DE AL MENOS 50% DE MOLECULAS QUE TIENEN PESOS MOLECULARES APARENTES SUPERIORES A 2000, CONSISTIENDO ESTA PROPORCION EN AL MENOS 40% DE PROANTOCIAMIDOLES, EXPRESANDOSE ESTE PORCENTAJE EN FUNCION TOMATO, Y EN QUE DICHA COMPOSICION ESTA ESENCIALMENTE EXENTA: DE ESENCIAS AROMATICAS Y EN PARTICULAR DE ACEITES ESENCIALES, DE RESINAS Y OTRAS SUSTANCIAS LIPOFILAS; AZUCARES POLIMERIZADOS TALES COMO EL ALMIDON; LAS GOMAS, LOS DERIVADOS CELULOSICOS; AZUCARES OLIGOMEROS TALES COMO LA SACAROSA, LA GLUCOSA, LA LEVULOSA. TAMBIEN SE REFIERE A LA APLICACION DE ESTA COMPOSICION EN COMPOSICIONES FARMACEUTICAS.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8906282A FR2646852B1 (fr) | 1989-05-12 | 1989-05-12 | Produit polyphenolique a activite antivirale |
| FR8907654A FR2648047B2 (fr) | 1989-05-12 | 1989-06-09 | Produit polyphenolique a activite antivirale |
| FR8913297A FR2652743B1 (fr) | 1989-10-11 | 1989-10-11 | Composition a base de proanthocyanidols. leur application pharmacologique. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2078339T3 true ES2078339T3 (es) | 1995-12-16 |
Family
ID=27251886
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES90905558T Expired - Lifetime ES2078339T3 (es) | 1989-05-12 | 1990-03-23 | Composiciones a base de proantocianidoles; su aplicacion farmacologica. |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP0472531B1 (es) |
| JP (1) | JPH05504937A (es) |
| AT (1) | ATE126439T1 (es) |
| AU (1) | AU648754B2 (es) |
| CA (1) | CA2057023A1 (es) |
| DE (1) | DE69021725T2 (es) |
| DK (1) | DK0472531T3 (es) |
| ES (1) | ES2078339T3 (es) |
| OA (1) | OA09558A (es) |
| WO (1) | WO1990013304A1 (es) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5211944A (en) * | 1990-10-12 | 1993-05-18 | Shaman Pharmaceuticals, Inc. | Proanthocyanidin polymers having antiviral activity and methods of obtaining same |
| DE4221537A1 (de) * | 1992-07-01 | 1994-01-05 | Schwabe Willmar Gmbh & Co | Hamamelis-Trockenextrakt, Verfahren zu seiner Herstellung und seine Verwendung als Arzneimittel |
| US5650432A (en) * | 1995-03-24 | 1997-07-22 | Jlb, Inc. | Method of treating or preventing non-viral microbial infection |
| US5646178A (en) * | 1992-10-09 | 1997-07-08 | Jlb, Inc. | Cranberry extract and biologically active compounds derived therefrom |
| WO1994023732A1 (en) * | 1993-04-08 | 1994-10-27 | Kambourakis Medicinal Solutions Pty. Limited | Therapeutic preparations containing cypress tree extracts and methods of using same |
| FI955691L (fi) * | 1994-11-28 | 1996-05-29 | Suntory Ltd | Lipoproteiini(a):ta alentava aine, kolesterolia alentava aine ja näitä aineita sisältävät lääkkeet |
| US5817299A (en) * | 1996-11-01 | 1998-10-06 | E-L Management Corp. | Non-chemical sunscreen composition |
| DK0998296T3 (da) * | 1997-07-24 | 2002-09-30 | Zografos Dietetic Products S A | Farmaceutiske anvendelser af cypres |
| US6207842B1 (en) | 1997-10-09 | 2001-03-27 | Mars Incorporated | Process for preparing procyanidin(4-6 or 4-8) oligomers and their derivatives |
| GR1003099B (el) * | 1998-04-22 | 1999-03-22 | ��������-�������� ������� �.�.�.�. �������� ��� ������� ������... | Ουσιες, φυσικης ή συνθετικης προελευσης, που ανηκουν στις ομαδες των τερπενοειδων, πολυφαινολων και προανθοκυανιδων, για χρηση στην προληψη και θεραπεια καθε τυπου υπερχοληστεριναιμιας και διαταραχης λιπιδιων, σε ανθρωπους και ζωα |
| FR2790645B1 (fr) | 1999-03-12 | 2001-06-08 | Arkopharma Laboratoires | Complement alimentaire et procede de traitement cosmetique a base d' un extrait de raisin riche en polyphenols |
| US6156912A (en) * | 1999-04-09 | 2000-12-05 | Mars, Incorporated | 88, 66, and 68 catechin and epicatechin dimers and methods for their preparation |
| US7015338B1 (en) | 1999-04-15 | 2006-03-21 | Mars Incorporated | Synthetic methods for preparing procyanidin oligomers |
| US6210681B1 (en) * | 1999-09-07 | 2001-04-03 | Jlb, Inc. | Plant proanthocyanidin extracts |
| US6476241B1 (en) | 2000-09-05 | 2002-11-05 | Mars Incorporated | Synthesis of 4α-arylepicatechins |
| FR2836337B1 (fr) * | 2002-02-28 | 2004-11-19 | Bio Serae Laboratoires | Utilisation des polymeres procyanidoliques a titre d'agents inhibuteurs des alpha-amylases et application dans des compositions a visees dietetiques |
| US7067679B2 (en) | 2002-10-02 | 2006-06-27 | Mars, Inc. | Synthesis of dimeric, trimeric, tetrameric pentameric, and higher oligomeric epicatechin-derived procyanidins having 4,8-interflavan linkages and their use to inhibit cancer cell growth through cell cycle arrest |
| ES2245610B1 (es) * | 2004-06-23 | 2007-03-16 | Investigacion Y Nutricion, S.L. | Producto de origen vegetal y su procedimiento de obtencion. |
| JP5253862B2 (ja) * | 2008-03-31 | 2013-07-31 | 株式会社ナリス化粧品 | メラニン産性抑制剤・コラーゲン産生促進剤 |
| KR101153630B1 (ko) * | 2009-10-16 | 2012-06-18 | 웅진코웨이주식회사 | 타닌산을 포함하는 인플루엔자 바이러스 감염의 예방용 조성물, 상기 조성물을 포함하는 기상필터 및 상기 필터를 포함하는 공기청정기 |
| JP5343016B2 (ja) * | 2010-01-22 | 2013-11-13 | 株式会社ロッテ | 抗インフルエンザウイルス剤及びこれを吸着、含浸、添加させてなるインフルエンザ感染抑制用品 |
| CN110090235A (zh) * | 2018-01-30 | 2019-08-06 | 学校法人北里研究所 | 含有由麻黄提取物或efe得到的高分子缩合型鞣质的提取分级物及其制法和用途 |
| CN114794473A (zh) * | 2022-04-24 | 2022-07-29 | 广东青云山药业有限公司 | 一种具有抑制age生成活性的樱花粉的制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4335110A (en) * | 1979-08-23 | 1982-06-15 | Orewa Inc. | Pharmaceutical compositions of sanguinaria galangal and zinc chloride |
| JPS61205272A (ja) * | 1985-03-08 | 1986-09-11 | Tsumura Juntendo Inc | 新規なタンニン |
| US4698360B1 (en) * | 1985-04-09 | 1997-11-04 | D Investigations Pharmacologiq | Plant extract with a proanthocyanidins content as therapeutic agent having radical scavenger effect and use thereof |
-
1990
- 1990-03-23 AU AU54000/90A patent/AU648754B2/en not_active Ceased
- 1990-03-23 WO PCT/FR1990/000200 patent/WO1990013304A1/fr not_active Application Discontinuation
- 1990-03-23 EP EP90905558A patent/EP0472531B1/fr not_active Revoked
- 1990-03-23 AT AT90905558T patent/ATE126439T1/de not_active IP Right Cessation
- 1990-03-23 JP JP2505329A patent/JPH05504937A/ja active Pending
- 1990-03-23 DE DE69021725T patent/DE69021725T2/de not_active Expired - Fee Related
- 1990-03-23 ES ES90905558T patent/ES2078339T3/es not_active Expired - Lifetime
- 1990-03-23 DK DK90905558.4T patent/DK0472531T3/da active
- 1990-03-23 CA CA002057023A patent/CA2057023A1/fr not_active Abandoned
-
1991
- 1991-11-12 OA OA60096A patent/OA09558A/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE69021725T2 (de) | 1996-04-18 |
| AU648754B2 (en) | 1994-05-05 |
| EP0472531B1 (fr) | 1995-08-16 |
| DK0472531T3 (da) | 1996-01-02 |
| ATE126439T1 (de) | 1995-09-15 |
| AU5400090A (en) | 1990-11-29 |
| OA09558A (fr) | 1993-01-31 |
| EP0472531A1 (fr) | 1992-03-04 |
| WO1990013304A1 (fr) | 1990-11-15 |
| JPH05504937A (ja) | 1993-07-29 |
| CA2057023A1 (fr) | 1990-11-13 |
| DE69021725D1 (de) | 1995-09-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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