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ES2070774B1 - LIPOSOMIC PREPARATIONS OF DRUGS OR VACCINE ANTIGENS FOR VETERINARY MEDICINE. - Google Patents

LIPOSOMIC PREPARATIONS OF DRUGS OR VACCINE ANTIGENS FOR VETERINARY MEDICINE.

Info

Publication number
ES2070774B1
ES2070774B1 ES9301968A ES9301968A ES2070774B1 ES 2070774 B1 ES2070774 B1 ES 2070774B1 ES 9301968 A ES9301968 A ES 9301968A ES 9301968 A ES9301968 A ES 9301968A ES 2070774 B1 ES2070774 B1 ES 2070774B1
Authority
ES
Spain
Prior art keywords
liposomic
liposomes
preparations
drugs
veterinary medicine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES9301968A
Other languages
Spanish (es)
Other versions
ES2070774A1 (en
Inventor
Gifre Juan Nogareda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratorios Hipra SA
Original Assignee
Laboratorios Hipra SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorios Hipra SA filed Critical Laboratorios Hipra SA
Priority to ES9301968A priority Critical patent/ES2070774B1/en
Publication of ES2070774A1 publication Critical patent/ES2070774A1/en
Application granted granted Critical
Publication of ES2070774B1 publication Critical patent/ES2070774B1/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)

Abstract

PREPARACIONES LIPOSOMICAS DE FARMACOS O ANTIGENOS VACUNALES PARA MEDICINA VETERINARIA. LAS PREPARACIONES LIPOSOMICAS CONTIENEN A LOS FARMACOS UTILIZADOS, BIEN EN EL INTERIOR DE LOS LIPOSOMAS, COMO SOLUCION ACUOSA, O BIEN EN LA BICAPA FOSFOLIPIDICA QUE FORMA LOS LIPOSOMAS. CUANDO LOS LIPOSOMAS CONTIENEN ANTIGENOS VACUNALES, ESTOS SE ENCUENTRAN EN EL INTERIOR DE LOS LIPOSOMAS O EN LA BICAPA. LOS FOSFOLIPIDOS UTILIZADOS, DE ORIGEN NATURAL, SEMISINTETICO O SINTETICO, SE ACOMPAÑAN DE ANTIOXIDANTES Y ESTABILIZANTES. LOS LIPOSOMAS TIENEN UN DIAMETRO MAXIMO DE 0,2 MICRAS, Y HAN SIDO ESTERILIZADOS Y ESTABILIZADOS PARA EL MANTENIMIENTO DE SUS CARACTERISTICAS HASTA EL MOMENTO DE SU APLICACION. LAS PREPARACIONES LIPOSOMICAS SE UTILIZAN PARA LA APLICACION DE FARMACOS O ANTIGENOS VACUNALES POR VIA PARENTERAL, INTRAVENOSA, INTRAMUSCULAR O INTRAPERITONEAL, EN CUALQUIER ESPECIE ANIMAL, DEJANDO MENOS RESIDUOS EN LOS TEJIDOS ANIMALES Y OCASIONANDO MENORES LESIONES QUE LAS FOMULACIONES TRADICIONALES.LIPOSOMIC PREPARATIONS OF DRUGS OR VACCINE ANTIGENS FOR VETERINARY MEDICINE. THE LIPOSOMIC PREPARATIONS CONTAIN THE DRUGS USED, EITHER INSIDE THE LIPOSOMES, AS AN AQUEOUS SOLUTION, OR IN THE PHOSPHOLIPIDIC LAYER THAT FORMS THE LIPOSOMES. WHEN LIPOSOMES CONTAIN VACCINAL ANTIGENS, THESE ARE LOCATED INSIDE THE LIPOSOMES OR IN THE TWO-LAYER. THE PHOSPHOLIPIDS USED, OF NATURAL ORIGIN, SEMI-SYNTHETIC OR SYNTHETIC, ARE ACCOMPANIED BY ANTIOXIDANTS AND STABILIZERS. LIPOSOMES HAVE A MAXIMUM DIAMETER OF 0.2 MICRONS, AND HAVE BEEN STERILIZED AND STABILIZED FOR THE MAINTENANCE OF THEIR CHARACTERISTICS UNTIL THE TIME OF THEIR APPLICATION. LIPOSOMIC PREPARATIONS ARE USED FOR THE APPLICATION OF PHARMACES OR VACCINAL ANTIGENS BY PARENTERAL, INTRAVENOUS, INTRAMUSCULAR OR INTRAPERITONEAL ROUTE, IN ANY ANIMAL SPECIES, LEAVING LESS RESIDUES IN ANIMAL TISSUES AND OCCASIONS.

ES9301968A 1993-09-16 1993-09-16 LIPOSOMIC PREPARATIONS OF DRUGS OR VACCINE ANTIGENS FOR VETERINARY MEDICINE. Expired - Lifetime ES2070774B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES9301968A ES2070774B1 (en) 1993-09-16 1993-09-16 LIPOSOMIC PREPARATIONS OF DRUGS OR VACCINE ANTIGENS FOR VETERINARY MEDICINE.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES9301968A ES2070774B1 (en) 1993-09-16 1993-09-16 LIPOSOMIC PREPARATIONS OF DRUGS OR VACCINE ANTIGENS FOR VETERINARY MEDICINE.

Publications (2)

Publication Number Publication Date
ES2070774A1 ES2070774A1 (en) 1995-06-01
ES2070774B1 true ES2070774B1 (en) 1995-11-01

Family

ID=8283065

Family Applications (1)

Application Number Title Priority Date Filing Date
ES9301968A Expired - Lifetime ES2070774B1 (en) 1993-09-16 1993-09-16 LIPOSOMIC PREPARATIONS OF DRUGS OR VACCINE ANTIGENS FOR VETERINARY MEDICINE.

Country Status (1)

Country Link
ES (1) ES2070774B1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2129342B1 (en) * 1996-12-19 2000-03-16 Hipra Lab Sa "FORMULATION OF LIPOSOMAL VACCINES AND THEIR PREPARATION".

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57147430A (en) * 1981-03-06 1982-09-11 Kureha Chem Ind Co Ltd Preparation of microcapsule
WO1993004672A1 (en) * 1991-09-11 1993-03-18 Pitman-Moore, Inc. Method for enhancing the immune system in a host employing liposome-encapsulated polypeptides

Also Published As

Publication number Publication date
ES2070774A1 (en) 1995-06-01

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