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ES2064074T3 - Procedimiento y aparato para separar y volver a poner en suspension particulas superparamagneticas. - Google Patents

Procedimiento y aparato para separar y volver a poner en suspension particulas superparamagneticas.

Info

Publication number
ES2064074T3
ES2064074T3 ES91900016T ES91900016T ES2064074T3 ES 2064074 T3 ES2064074 T3 ES 2064074T3 ES 91900016 T ES91900016 T ES 91900016T ES 91900016 T ES91900016 T ES 91900016T ES 2064074 T3 ES2064074 T3 ES 2064074T3
Authority
ES
Spain
Prior art keywords
pct
container
particles
suspension
fluid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91900016T
Other languages
English (en)
Inventor
Tor Erling Lea
Bjorn Kirkaas Pedersen
Harald Kristian Naess
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Diatec Instruments AS
Original Assignee
Diatec Instruments AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Diatec Instruments AS filed Critical Diatec Instruments AS
Application granted granted Critical
Publication of ES2064074T3 publication Critical patent/ES2064074T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/24—Methods of sampling, or inoculating or spreading a sample; Methods of physically isolating an intact microorganisms
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00—Magnetic separation
    • B03C1/02—Magnetic separation acting directly on the substance being separated
    • B03C1/28—Magnetic plugs and dipsticks
    • B03C1/288—Magnetic plugs and dipsticks disposed at the outer circumference of a recipient
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C2201/00—Details of magnetic or electrostatic separation
    • B03C2201/26—Details of magnetic or electrostatic separation for use in medical or biological applications
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0098—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Compounds Of Iron (AREA)
  • Compounds Of Alkaline-Earth Elements, Aluminum Or Rare-Earth Metals (AREA)

Abstract

LAS PARTICULAS SUPERPARAMAGNETICAS SE SEPARAN DE UNA SUSPENSION DE LAS MISMAS EN UN PRIMER FLUIDO Y SE VUELVEN A SUSPENDER EN EL MISMO FLUIDO O EN OTRO DISTINTO QUE SE ENCUENTRA EN UN CONTENEDOR, A BASE DE SOMETERLAS A UN PRIMER CAMPO ELECTROMAGNETICO PARA LLEVAR LAS PARTICULAS A UNA SUPERFICIE O ZONA DEL CONTENEDOR Y DESPUES VOLVER A SUSPENDER LAS PARTICULAS EN EL FLUIDO QUE SE ENCUENTRA EN EL CONTENEDOR MEDIANTE UNA SEGUNDA APLICACION DE UN CAMPO MAGNETICO. SE PRESENTA UN APARATO QUE CONTIENE EL CONTENEDOR (1), MEDIOS (2, 3) PARA PRODUCIR DICHAS PRIMERA Y SEGUNDA APLICACIONES DE CAMPOS ELECTROMAGNETICOS, RECEPTACULOS REACTIVOS (7) Y UNA FRASCO DE LAVADO (8). SE PUEDE INCLUIR TAMBIEN UN DISPOSITIVOS CONTADOR DE PARTICULAS Y TAL APARATO SE PUEDE UTILIZAR PARA CONTAR CELULAS.
ES91900016T 1989-12-07 1990-12-06 Procedimiento y aparato para separar y volver a poner en suspension particulas superparamagneticas. Expired - Lifetime ES2064074T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898927744A GB8927744D0 (en) 1989-12-07 1989-12-07 Process and apparatus

Publications (1)

Publication Number Publication Date
ES2064074T3 true ES2064074T3 (es) 1995-01-16

Family

ID=10667610

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91900016T Expired - Lifetime ES2064074T3 (es) 1989-12-07 1990-12-06 Procedimiento y aparato para separar y volver a poner en suspension particulas superparamagneticas.

Country Status (11)

Country Link
US (1) US5681478A (es)
EP (1) EP0504192B1 (es)
JP (1) JPH05502294A (es)
AT (1) ATE114047T1 (es)
AU (1) AU642186B2 (es)
CA (1) CA2072135A1 (es)
DE (1) DE69014130T2 (es)
DK (1) DK0504192T3 (es)
ES (1) ES2064074T3 (es)
GB (1) GB8927744D0 (es)
WO (1) WO1991009308A1 (es)

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US6884357B2 (en) * 1995-02-21 2005-04-26 Iqbal Waheed Siddiqi Apparatus and method for processing magnetic particles
US20030127396A1 (en) * 1995-02-21 2003-07-10 Siddiqi Iqbal Waheed Apparatus and method for processing magnetic particles
EP0810905B1 (en) 1995-02-21 1998-11-04 Iqbal W. Dr. Siddiqi Apparatus and method for mixing and separation employing magnetic particles
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AU737298B2 (en) 1997-05-05 2001-08-16 Chemometec A/S A method and a system for determination of somatic cells in milk
DE19823719B4 (de) * 1998-05-27 2011-12-15 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Verfahren zum Aufkonzentrieren von Substanzen
WO2000062034A2 (en) 1999-04-09 2000-10-19 Shot, Inc. Multistage electromagnetic separator for purifying cells, chemicals and protein structures
US6672458B2 (en) 2000-05-19 2004-01-06 Becton, Dickinson And Company System and method for manipulating magnetically responsive particles fluid samples to collect DNA or RNA from a sample
US20030095897A1 (en) * 2001-08-31 2003-05-22 Grate Jay W. Flow-controlled magnetic particle manipulation
JP2005511066A (ja) * 2001-12-07 2005-04-28 ダイアックス、コープ 磁気応答性粒子を洗浄する方法及び装置
EP1494814A1 (en) 2002-04-12 2005-01-12 Instrumentation Laboratory Company Immunoassay probe
WO2003097808A2 (en) 2002-05-17 2003-11-27 Becton, Dickinson And Company Automated system for isolating, amplyifying and detecting a target nucleic acid sequence
US7601491B2 (en) * 2003-02-06 2009-10-13 Becton, Dickinson And Company Pretreatment method for extraction of nucleic acid from biological samples and kits therefor
JP3711988B2 (ja) * 2003-05-12 2005-11-02 株式会社日立製作所 微粒子アレー分析システム、微粒子アレーキットおよび化学分析方法
US7700276B2 (en) * 2003-07-10 2010-04-20 Universite Libre De Bruxelles Device, kit and method for pulsing biological samples with an agent and stabilising the sample so pulsed
US7947450B2 (en) 2003-07-10 2011-05-24 Universite Libre De Bruxelles Device, kit and method for pulsing biological samples with an agent and stabilising the sample so pulsed
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US8870446B2 (en) 2006-06-21 2014-10-28 Spinomix S.A. Device and method for manipulating and mixing magnetic particles in a liquid medium
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US8585279B2 (en) 2006-06-21 2013-11-19 Spinomix S.A. Device and method for manipulating and mixing magnetic particles in a liquid medium
JP2010508404A (ja) * 2006-10-30 2010-03-18 エスティーシー． ユーエヌエム 磁気感受性粒子およびその混合装置
EP2121194A2 (en) * 2006-12-20 2009-11-25 Philips Intellectual Property & Standards GmbH Method and arrangement for separating magnetic particles, magnetic particles and use magnetic particles
WO2010068812A1 (en) * 2008-12-10 2010-06-17 Abqmr, Inc. Nuclear magnetic resonance apparatus, methods and associated technology
EP2368639A1 (de) * 2010-03-23 2011-09-28 Siemens Aktiengesellschaft Vorrichtung und Verfahren zur Magnetseparation eines Fluids
US9428547B2 (en) 2010-04-21 2016-08-30 Dna Electronics, Inc. Compositions for isolating a target analyte from a heterogeneous sample
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US8841104B2 (en) 2010-04-21 2014-09-23 Nanomr, Inc. Methods for isolating a target analyte from a heterogeneous sample
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US20120135494A1 (en) * 2010-11-30 2012-05-31 General Electric Company Systems and methods for magnetic separation of biological materials
GB2497317A (en) * 2011-12-06 2013-06-12 Univ Dublin System and method for the detection of analytes using rod-shaped nanoparticles
DE102012210077A1 (de) * 2012-06-15 2013-12-19 Siemens Aktiengesellschaft Verfahren und Anordnung zur Markierung von Zellen in einer Zellsuspension
US10000557B2 (en) 2012-12-19 2018-06-19 Dnae Group Holdings Limited Methods for raising antibodies
US9804069B2 (en) 2012-12-19 2017-10-31 Dnae Group Holdings Limited Methods for degrading nucleic acid
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US9995742B2 (en) 2012-12-19 2018-06-12 Dnae Group Holdings Limited Sample entry
US9599610B2 (en) 2012-12-19 2017-03-21 Dnae Group Holdings Limited Target capture system
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US10953092B2 (en) * 2015-09-22 2021-03-23 California Institute Of Technology Method and apparatus for particle actuation in a space
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Also Published As

Publication number Publication date
AU642186B2 (en) 1993-10-14
GB8927744D0 (en) 1990-02-07
DE69014130T2 (de) 1995-03-23
DK0504192T3 (da) 1995-01-02
DE69014130D1 (de) 1994-12-15
WO1991009308A1 (en) 1991-06-27
CA2072135A1 (en) 1991-06-08
ATE114047T1 (de) 1994-11-15
EP0504192B1 (en) 1994-11-09
JPH05502294A (ja) 1993-04-22
US5681478A (en) 1997-10-28
EP0504192A1 (en) 1992-09-23
AU6879391A (en) 1991-07-18

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