ES2058602T3 - Preparados del oxipurinol y/o de sales de metales alcalinos o alcalinoterreos. - Google Patents
Preparados del oxipurinol y/o de sales de metales alcalinos o alcalinoterreos.Info
- Publication number
- ES2058602T3 ES2058602T3 ES89912952T ES89912952T ES2058602T3 ES 2058602 T3 ES2058602 T3 ES 2058602T3 ES 89912952 T ES89912952 T ES 89912952T ES 89912952 T ES89912952 T ES 89912952T ES 2058602 T3 ES2058602 T3 ES 2058602T3
- Authority
- ES
- Spain
- Prior art keywords
- alkaline
- oxipurinol
- salts
- prepared
- terrain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- HXNFUBHNUDHIGC-UHFFFAOYSA-N oxypurinol Chemical compound O=C1NC(=O)N=C2NNC=C21 HXNFUBHNUDHIGC-UHFFFAOYSA-N 0.000 title abstract 4
- 229950002752 oxipurinol Drugs 0.000 title abstract 3
- 229910052751 metal Inorganic materials 0.000 title 1
- 239000002184 metal Substances 0.000 title 1
- 150000002739 metals Chemical class 0.000 title 1
- 238000002360 preparation method Methods 0.000 abstract 2
- 239000000126 substance Substances 0.000 abstract 2
- 239000012190 activator Substances 0.000 abstract 1
- 239000006185 dispersion Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physical Education & Sports Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Inorganic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
LAS PREPARACIONES DE OXIPURINOL Y/O DE SUS SALES DE ALCALI O DE ALCALITERREO EN UNA FORMA NO CRISTALIZADA CONTIENEN ACTIVADORES EN FORMA DE UNA DISPERSION DE MATERIA FIJA CON SUSTANCIAS AUXILIARES NO PENSADAS FARMACOLOGICAMENTE. TIENEN UNA ALTA Y RAPIDA SOLUBILIDAD SOBRE EL OXIPURINOL Y/O SUS SALES DE ALCALI O DE ALCALITERREO. SE PUEDEN UTILIZAR PARA LA ELABORACION DE MEDICAMENTOS CON UN ALTO GRADO DE LA SUSTANCIA OXIPURINOL.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3839825A DE3839825A1 (de) | 1988-11-25 | 1988-11-25 | Feststoffdispersionen enthaltend oxipurinol und/oder seine alkali- oder erdalkalisalze |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2058602T3 true ES2058602T3 (es) | 1994-11-01 |
Family
ID=6367881
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES89912952T Expired - Lifetime ES2058602T3 (es) | 1988-11-25 | 1989-11-24 | Preparados del oxipurinol y/o de sales de metales alcalinos o alcalinoterreos. |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0445158B1 (es) |
JP (1) | JP2965689B2 (es) |
DE (2) | DE3839825A1 (es) |
ES (1) | ES2058602T3 (es) |
WO (1) | WO1990006115A2 (es) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0617612B1 (en) | 1991-12-18 | 1997-09-10 | Warner-Lambert Company | A process for the preparation of a solid dispersion |
DE4406462C2 (de) * | 1994-02-24 | 1997-05-28 | Jenapharm Gmbh | Verfahren und Vorrichtung zur Herstellung fester Dispersionen |
JP2000281561A (ja) * | 1999-03-26 | 2000-10-10 | Ajinomoto Co Inc | 新規溶媒法固体分散体製剤 |
US7364752B1 (en) | 1999-11-12 | 2008-04-29 | Abbott Laboratories | Solid dispersion pharamaceutical formulations |
JP5767429B2 (ja) * | 1999-11-12 | 2015-08-19 | アッヴィ・インコーポレイテッド | 固体分散剤中の結晶化阻害剤 |
DE10000792A1 (de) * | 2000-01-11 | 2001-07-19 | Bernhard C Lippold | Formulierungen von Wirkstoffen in Form einer festen Dispersion |
DE10026698A1 (de) | 2000-05-30 | 2001-12-06 | Basf Ag | Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung |
US8025899B2 (en) | 2003-08-28 | 2011-09-27 | Abbott Laboratories | Solid pharmaceutical dosage form |
WO2009118356A2 (en) * | 2008-03-25 | 2009-10-01 | Formac Pharmaceuticals N.V. | Preparation method for solid disupersions |
JPWO2016010093A1 (ja) * | 2014-07-16 | 2017-04-27 | 株式会社セラバリューズ | 非晶質クルクミン及び/又はその類縁体を含有する複合体の製造方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB975850A (en) * | 1955-08-10 | 1964-11-18 | Wellcome Found | Xanthine oxidase inhibitors |
GB1460302A (en) * | 1973-05-23 | 1977-01-06 | Wellcome Found | Tablet formulation |
DE2546371A1 (de) * | 1975-10-16 | 1977-04-21 | Sandoz Ag | Neue galenische formen |
EP0237348B1 (en) * | 1986-03-13 | 1990-09-05 | The Wellcome Foundation Limited | Cell protection |
-
1988
- 1988-11-25 DE DE3839825A patent/DE3839825A1/de active Granted
-
1989
- 1989-11-24 JP JP2500187A patent/JP2965689B2/ja not_active Expired - Lifetime
- 1989-11-24 ES ES89912952T patent/ES2058602T3/es not_active Expired - Lifetime
- 1989-11-24 EP EP89912952A patent/EP0445158B1/de not_active Expired - Lifetime
- 1989-11-24 WO PCT/EP1989/001425 patent/WO1990006115A2/de active IP Right Grant
- 1989-11-24 DE DE8989912952T patent/DE58905187D1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0445158A1 (de) | 1991-09-11 |
DE3839825A1 (de) | 1990-06-13 |
DE3839825C2 (es) | 1992-04-16 |
JP2965689B2 (ja) | 1999-10-18 |
JPH04502004A (ja) | 1992-04-09 |
DE58905187D1 (de) | 1993-09-09 |
EP0445158B1 (de) | 1993-08-04 |
WO1990006115A2 (de) | 1990-06-14 |
WO1990006115A3 (de) | 1990-08-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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